Eleuphrat

Land: Australia

Språk: engelsk

Kilde: Department of Health (Therapeutic Goods Administration)

Aktiv ingrediens:

Betamethasone dipropionate

Tilgjengelig fra:

Merck Sharp & Dohme Australia Pty Ltd

Klasse:

Medicine Registered

Informasjon til brukeren

ELEUPHRAT
®

_Betamethasone dipropionate_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about Eleuphrat.
It does not contain all the available
information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you using Eleuphrat
against the benefits it is expected to
have for you.
IF YOU HAVE ANY CONCERNS ABOUT THIS
MEDICINE, ASK YOUR DOCTOR OR
PHARMACIST.
KEEP THIS LEAFLET WITH YOUR
MEDICINE.
You may need to read it again.
WHAT ELEUPHRAT IS
USED FOR
The name of your medicine is
Eleuphrat. It contains the active
ingredient called betamethasone
dipropionate.
It is a type of cortisone and belongs
to the group of medicines called
corticosteroids. Eleuphrat is
classified as a high potency topical
corticosteroid.
There are two forms of Eleuphrat:
cream and ointment
Eleuphrat is used on the skin to
relieve the redness, swelling, itching
and discomfort of many skin
problems such as:
•
psoriasis (a stubborn skin
disorder with raised, rough,
reddened areas covered with dry,
fine silvery scales)
•
eczema (an often itchy skin
condition with redness, swelling,
oozing of fluid, crusting which
may lead to scaling)
•
other types of dermatitis
Your doctor may have prescribed
Eleuphrat for another reason.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY ELEUPHRAT HAS
BEEN PRESCRIBED FOR YOU.
This medicine is available only with
a doctor's prescription.
BEFORE YOU USE
ELEUPHRAT
_WHEN YOU MUST NOT USE IT_
DO NOT USE ELEUPHRAT IF YOU HAVE
HAD AN ALLERGIC REACTION (SUCH AS
WHEEZING, RASH OR HIVES) TO:
•
BETAMETHASONE DIPROPIONATE
•
ANY OTHER CORTICOSTEROID
•
ANY OF THE INGREDIENTS LISTED AT
THE END OF THIS LEAFLET
DO NOT USE ELEUPHRAT IF YOU HAVE:
•
A VIRAL SKIN INFECTION, SUCH AS
COLD SORES, SHINGLES OR CHICKEN
POX
•
A FUNGAL SKIN INFECTION, SUCH AS
THRUSH, TINEA OR RINGWORM
•
TUBERCULOSIS OF THE SKIN
•
ACNE ROSACEA
•
INFLAMMATION AROUND THE
MOUTH
•
S

Preparatomtale

 
PI ref.: A110922Version 3 
1 

PRODUCT INFORMATION 

ELEUPHRAT CREAM, OINTMENT AND LOTION 

NAME OF THE MEDICINE  

Betamethasone dipropionate equivalent to betamethasone 0.5 mg/g
(0.05%  w /w ) 

Chemical Structure:  

Betamethasone dipropionate is 9-fluoro-11
β,17,21-trihydroxy-16β-methylpregna-1,4-diene-
3,20-dione 17,21-dipropionate.  The empirical formula is C
28
H
37
FO
7
.  MW =  504.6 

DESCRIPTION 

ELEUPHRAT CREAM  (0.05%  w /w ): Each g
contains betamethasone dipropionate equivalent to 
betamethasone 0.5 mg. The
cream base consists of chlorocresol 1 mg/g
as preservative, soft 
w hite paraffin, liquid paraffin, cetostearyl alcohol, cetomacrogol 1000, sodium phosphate 
monobasic, phosphoric acid and purified w ater. 

ELEUPHRAT OINTMENT (0.05%  w /w ): Each g
contains betamethasone dipropionate equivalent to 
betamethasone  0.5 mg in an ointment base consisting of soft w hite paraffin and liquid 
paraffin. 

ELEUPHRAT LOTION  (0.05%  w /w ): Each
mL contains betamethasone dipropionate equivalent to 
betamethasone 0.47 mg in a vehicle consisting
of isopropyl alcohol, carbomer 934P, sodium 
hydroxide and purified w ater. 

PHARMACOLOGY 

Betamethasone dipropionate is a potent topically-active corticosteroid producing prompt, 
marked and prolonged anti-inflammatory, anti-pruritic and
vasoconstrictive effects.   

According to the McKenzie-Stoughton Vasoconstrictor Test, betamethasone dipropionate 
w as demonstrated to be significantly more active
(p< 0.05) than betamethasone valerate, 
fluocortolone, and flumethasone pivalate. While the direct applicability of this vasoconstrictor 
test to clinical situations has not been demonstrated
conclusively, the results show ed 
betamethasone dipropionate to be active in
a concentration of 0.000016% , the low est 
concentration tested