Land: Australia
Språk: engelsk
Kilde: Department of Health (Therapeutic Goods Administration)
Diclofenac sodium
Sandoz Pty Ltd
Diclofenac sodium
_ _ _ _ Diclofenac AN _ _ 1 DICLOFENAC AN _ _ _Diclofenac sodium _ CONSUMER MEDICINE INFORMATION (CMI) WHAT IS IN THIS LEAFLET This leaflet answers some of the common questions about Diclofenac AN. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Diclofenac AN against the benefits they expect it will have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Keep this leaflet with the medicine. You may want to read it again. WHAT DICLOFENAC AN TABLETS ARE USED FOR The name of your medicine is Diclofenac AN. It contains the active ingredient diclofenac sodium. Diclofenac AN is used for treating the symptoms of inflammatory and degenerative forms of rheumatism, rheumatoid arthritis and osteoarthritis. It is also used in conditions where back pain, muscle strains, sprains and tendonitis (e.g. tennis elbow) are observed. It is also used to relieve states of acute or chronic in which there is an inflammatory component, as well as for the symptomatic treatment of dysmenorrhoea (heavy, painful periods). Your doctor may have prescribed Diclofenac AN for another reason. Ask your doctor if you have any questions about why Diclofenac AN was prescribed for you. Diclofenac AN belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It also has analgesic and antipyretic properties. Diclofenac acts by reducing pain (at rest and on movement), morning stiffness and swelling of the joints associated with rheumatic diseases, as well as improving function. In addition, it has been shown to relieve pain in dysmenorrhoea. There is no evidence that Diclofenac AN is addictive. BEFORE YOU TAKE DICLOFENAC AN TABLETS _WHEN YOU MUST NOT TAKE _ _DICLOFENAC AN TABLETS _ Diclofenac AN tablets should not be used by children. In adults, they should not be taken if: • You are allergic to the active ingredient or an Les hele dokumentet
_Product Information _ Page 1 _ _ _Diclofenac AN 25mg/50mg enteric-coated tablets _ _05/2017 _ _Sandoz Pty Ltd_ PRODUCT INFORMATION DICLOFENAC AN ® 25MG AND 50MG ENTERIC-COATED TABLETS NAME OF THE MEDICINE The name of the medicine is diclofenac sodium. Chemical Name: sodium 2- (2,6- dichlorophenyl)amino phenylacetate Molecular formula: C 14 H 10 Cl 2 NNaO 2 Molecular Weight: 318.13 CAS Registry Number: [ _15307-79-6_ ] DESCRIPTION Diclofenac sodium is an odourless, yellowish-white, crystalline powder sparingly soluble in water. _ _ _ _ In addition to diclofenac sodium, Diclofenac AN enteric coated tablets contain lactose, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, maize starch, sodium starch glycollate, magnesium stearate, colloidal anhydrous silica, methacrylic acid copolymer, triethyl citrate, purified talc, titanium dioxide and iron oxide yellow. PHARMACOLOGY Pharmacodynamics Diclofenac sodium, a nonsteroidal compound, exhibits pronounced antirheumatic, anti- inflammatory, analgesic and antipyretic properties. As with other NSAIDs, its mode of action is not known; however, its ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect. In rheumatic diseases, the anti-inflammatory and analgesic properties of Diclofenac AN elicit a clinical response characterised by relief from signs and symptoms such as pain at rest, pain CH 2 NH C O O Cl Cl Diclofenac Sodium Na + - _Product Information _ Page 2 _ _ _Diclofenac AN 25mg/50mg enteric-coated tablets _ _05/2017 _ _Sandoz Pty Ltd_ on movement, morning stiffness, and swelling of the joints, as well as by an improvement in function. In addition, clinical studies have revealed that in primary dysmenorrhoea diclofenac preparations are capable of relieving the pain and reducing the extent of bleeding. Low concentrations of diclofenac sodium inhibit the aggregation of platelets induced _in vitro_ by collagen and by adenosine diphosphate. Diclofenac sodium _in vitro_ does not suppress proteoglycan biosynthesis Les hele dokumentet