Land: USA
Språk: engelsk
Kilde: NLM (National Library of Medicine)
EPRINOMECTIN (UNII: 75KP30FD8O) (EPRINOMECTIN - UNII:75KP30FD8O), PRAZIQUANTEL (UNII: 6490C9U457) (PRAZIQUANTEL - UNII:6490C9U457)
Boehringer Ingelheim Animal Health USA Inc.
TRANSDERMAL
PRESCRIPTION
CENTRAGARD is indicated for the prevention of heartworm disease caused by Dirofilaria immitis , and for the treatment and control of roundworms (adult and fourth stage larval Toxocara cati ), hookworms (adult and fourth stage larval Ancylostoma tubaeforme ; adult Ancylostoma braziliense ), and tapeworms (adult Dipylidium caninum and Echinococcus multilocularis ) in cats and kittens 7 weeks of age and older and 1.8 lbs or greater.
CENTRAGARD is packaged as a single dose in 0.3 mL (for cats 1.8 – 5.5 lb) and 0.9 mL (for cats 5.6-16.5 lb) applicators. Each size applicator is available in cartons containing 1, 3 or 6 applications. Approved by FDA under NADA # 141-492 Manufactured for: Boehringer Ingelheim Animal Health USA Inc. Duluth, GA 30096 Made in France CENTRAGARD™ is a trademark of Boehringer Ingelheim Animal Health USA Inc. © 2019 Boehringer Ingeheim Animal Health USA Inc. All rights reserved. Revision date: Dec 2018
New Animal Drug Application
CENTRAGARD- EPRINOMECTIN AND PRAZIQUANTEL SOLUTION BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC. ---------- CENTRAGARD™ (EPRINOMECTIN AND PRAZIQUANTEL TRANSDERMAL SOLUTION) FOR CATS CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION CENTRAGARD is a transdermal solution containing eprinomectin and praziquantel available in 0.3 mL and 0.9 mL unit applicators to treat cats from 1.8 lbs to 33 lbs. Each mL of CENTRAGARD contains 4 mg of eprinomectin and 83 mg of praziquantel, as well as the inactive ingredients (dimethyl isosorbide, glycerol formal, and butylated hydroxytoluene). Eprinomectin belongs to the avermectin class of anthelmintics and is a mixture of homologous components referred to as eprinomectin B1a and B1b. Praziquantel is a pyrazinoisoquinoline anthelmintic. INDICATIONS CENTRAGARD is indicated for the prevention of heartworm disease caused by _Dirofilaria_ _immitis_, and for the treatment and control of roundworms (adult and fourth stage larval _Toxocara cati_), hookworms (adult and fourth stage larval _Ancylostoma tubaeforme_; adult _Ancylostoma braziliense_), and tapeworms (adult _Dipylidium caninum_ and _Echinococcus multilocularis_) in cats and kittens 7 weeks of age and older and 1.8 lbs or greater. DOSAGE AND ADMINISTRATION CENTRAGARD is dosed at a minimum of 0.055 mL/lb (0.12 mL/kg), which delivers a minimum dose of 0.23 mg/lb eprinomectin and 4.55 mg/lb praziquantel. Administer the entire contents of a CENTRAGARD unit applicator topically once a month as specified in the following table: CAT WEIGHT (LB) VOLUME (ML) EPRINOMECTIN (MG) PRAZIQUANTEL (MG) 1.8-5.5 0.3 1.2 24.9 5.6-16.5 0.9 3.6 74.7 16.6-22.0 0.3 + 0.9 4.8 99.6 22.1-33.0 0.9 + 0.9 7.2 149.4 To apply CENTRAGARD pull back the plunger of the unit applicator slightly and remove the cap. Part the hair in one spot on the midline of the neck between the base of the skull and the shoulder blades, place the tip of the unit applicator on the skin and apply the contents directly on the Les hele dokumentet