Land: New Zealand
Språk: engelsk
Kilde: Medsafe (Medicines Safety Authority)
Cefotaxime sodium 524.1mg equivalent to 500 mg cefotaxime;
Sandoz New Zealand Limited
Cefotaxime sodium 524.1 mg (equivalent to 500 mg cefotaxime)
500 mg
Powder for injection
Active: Cefotaxime sodium 524.1mg equivalent to 500 mg cefotaxime
Vial, glass, 1 x 500mg, 500 mg
Prescription
Prescription
Sandoz Industrial Products GmbH
Package - Contents - Shelf Life: Vial, glass, 500mg - 1 dose units - 24 months from date of manufacture stored at or below 25°C - Vial, glass, 500mg - 5 dose units - 24 months from date of manufacture stored at or below 25°C - Vial, glass, 500 mg - 10 dose units - 24 months from date of manufacture stored at or below 25°C
2000-08-16
CEFOTAXIME SANDOZ _CEFOTAXIME SODIUM PH EUR, POWDER FOR INJECTION, 500 MG, 1 G AND 2 G (AS _ _CEFOTAXIME) _ PRESENTATION Cefotaxime Sandoz powder for injection is a white to slightly yellowish powder aseptically filled into glass vials. Cefotaxime Sandoz 500 mg contains in a 15 ml vial, sterile Cefotaxime Sodium Ph Eur equivalent to cefotaxime 500 mg. Cefotaxime Sandoz 1 g contains in a 20 ml vial, sterile Cefotaxime Sodium Ph Eur equivalent to cefotaxime 1 g. Cefotaxime Sandoz 2 g contains in a 20 ml or 50 ml vial, sterile Cefotaxime Sodium Ph Eur equivalent to cefotaxime 2 g. USES _ACTIONS _ PHARMACOTHERAPEUTIC GROUP J01DD01 - Third generation cephalosporins, cefotaxime. MECHANISM OF ACTION Beta-lactam antibiotic. PHARMACODYNAMIC EFFECTS Inhibition of bacterial cell wall synthesis. ONSET AND DURATION OF ACTION The duration of treatment depends on the patient's response and therapy should be continued for at least three days after body temperature normalisation. ANTIBIOTIC CLASS Cefotaxime is a semisynthetic broad spectrum bactericidal cephalosporin antibiotic for parenteral use. ANTIBIOTIC NATURE AND MODE OF ACTION Cefotaxime is exceptionally active _in-vitro _against Gram-negative organisms sensitive or resistant to first or second generation cephalosporins. It is similar to other cephalosporins in activity against Gram-positive bacteria. Cefotaxime has been used with other beta-lactam antibiotics such as carbenicillin in the treatment of neutropenic patients. Cefotaxime Sandoz may also be administered with metronidazole in the treatment of mixed infections caused by anaerobic and aerobic organisms. SUSCEPTIBILITY DATA Dilution or diffusion techniques – either quantitative minimum inhibitory concentrations (MIC) or breakpoint, should be used following a regularly updated, recognised and standardised method (e.g. NCCLS). Standardised susceptibility test procedures require the use of laboratory contr Les hele dokumentet