Land: Storbritannia
Språk: engelsk
Kilde: MHRA (Medicines & Healthcare Products Regulatory Agency)
Adrenaline
base) for anaphylaxis 1mg/1ml (1 in 1,000) solution for injection pre-filled syringes (Martindale Pharmaceuticals Ltd
C01CA24
Adrenaline
1mg/1ml
Solution for injection
Subcutaneous; Intramuscular
No Controlled Drug Status
Valid as a prescribable product
BNF: 03040300; GTIN: 5026468000401
In emergencies it may be necessary to administer an adrenaline solution slowly into a vein (intravenous). Your doctor will decide the correct dosage for you and when and how the injection should be administered. DOSAGE: ADULTS: 500 micrograms (0.5 ml) of 1:1000 adrenaline solution given by injection into the muscle (intramuscular) CHILDREN: Volume of 1:1000 adrenaline to administer is shown in brackets. AGE DOSE Over 12 years 0.5 mg IM (0.5ml 1:1000 solution) 6 - 12 years 0.3 mg IM (0.3ml 1:1000 solution) 6 months - 6 years 0.15 mg IM (0.15ml 1:1000 solution) Under 6 months 0.01mg/kg IM (0.01ml/kg 1:1000 solution) Repeat the intramuscular dose if there is no improvement in the patients condition. Further doses can be given at 5 minute intervals according to the patient’s response. IF YOU ARE GIVEN MORE ADRENALINE INJECTION THAN YOU SHOULD As this medicine will be given to you whilst you are in hospital, it is unlikely that you will be given too little or too much, however, tell your doctor or nurse if you have any concerns. 4. POSSIBLE SIDE EFFECTS Like all medicines Adrenaline Injection can cause side effects, although not everybody gets them. IF YOU EXPERIENCE ANY OF THESE FOLLOWING SIDE EFFECTS, STOP TAKING THIS MEDICINE AND REPORT TO A DOCTOR IMMEDIATELY: • allergic reactions although serious allergic reactions are rare • any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body). Other side effects (Not known: frequency cannot be estimated from the available data): • headache • dizziness • feelings of anxiety or fear or restlessness • trembling • insomnia, confusion, irritability • abnormal mood or behaviour • a dry mouth or producing too much saliva • weakness or sweating • changes in the rhythm and speed of the heart • high blood pressure • coldness of the arms or legs • breathlessness • reduced appetite, feeling sick or being sick • repeated injections may damage tissues at the site of the Les hele dokumentet
OBJECT 1 ADRENALINE (EPINEPHRINE) INJECTION (1:1000) FOR ANAPHYLAXIS (GLASS PREFILLED SYRINGE) Summary of Product Characteristics Updated 20-Dec-2017 | Martindale Pharma 1. Name of the medicinal product Adrenaline (Epinephrine) (1:1000) Injection for Anaphylaxis 2. Qualitative and quantitative composition Each ml contains 1mg Adrenaline (Epinephrine) as the Acid Tartrate Excipient with known effect: Sodium metabisulfite: 0.90 – 1.10 mg/ml For the full list of excipients, see section 6.1. 3. Pharmaceutical form Solution for Injection Clear and colourless solution, practically free from particles 4. Clinical particulars 4.1 Therapeutic indications To provide rapid relief for Anaphylaxis or Acute Allergy (Angioedema) both to drugs and other allergens. 4.2 Posology and method of administration The intramuscular (IM) route is recommended by the UK Resuscitation Council as the most appropriate for most individuals who have to give adrenaline to treat an anaphylactic reaction. The subcutaneous route for adrenaline is not recommended for treatment of an anaphylactic reaction as it is less effective. Half doses of adrenaline may be safer for patients who are taking amitriptyline, imipramine or a beta blocker. Dosage: Adults: 500 micrograms (0.5ml) of 1:1000 adrenaline solution Elderly: There are no specific dosage regimes for adrenaline injection in elderly patients. However, Adrenaline should be used with great caution in these patients who may be more susceptible to the cardiovascular side effects of adrenaline. Paediatric population: The following doses of adrenaline 1/1,000 are recommended: Age Dose Over 12 years 0.5 mg IM (0.5ml 1:1000 solution) 6 - 12 years 0.3 mg IM (0.3ml 1:1000 solution) 6 months - 6 years 0.15 mg IM (0.15ml 1:1000 solution) Under 6 months 0.01mg/kg IM (0.01ml/kg 1:1000 solution) Repeat the IM adrenaline dose if there is no improvement in the patient's condition. Further doses can be given at about 5-minute intervals according to the patient's response. There is a much greater risk of causing h Les hele dokumentet