Land: Verenigde Staten
Taal: Engels
Bron: NLM (National Library of Medicine)
pyrantel pamoate (UNII: 81BK194Z5M) (pyrantel - UNII:4QIH0N49E7)
Zoetis Inc.
ORAL
OTC
For the removal and control of mature infections of large strongyles (Strongylus vulgaris, S. edentatus, S. equinus); small strongyles; pinworms (Oxyuris equi); and large roundworms (Parascaris equorum) in horses and ponies. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.
New Animal Drug Application
STRONGID- PYRANTEL PAMOATE PASTE ZOETIS INC. ---------- STRONGID PASTE (PYRANTEL PAMOATE) Equine Anthelmintic READ ENTIRE PACKAGE INSERT CAREFULLY BEFORE USING THIS PRODUCT DESCRIPTION Strongid Paste is a pale yellow to buff paste containing 43.9% w/w pyrantel pamoate in an inert vehicle. Each syringe contains 3.6 grams of pyrantel base in 23.6 grams (20 mL) paste. Each mL contains 180 mg pyrantel base as pyrantel pamoate. COMPOS ITION Pyrantel pamoate is a compound belonging to a family classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble crystalline salt of the tetrahydropyrimidine base and pamoic acid containing 34.7% base activity. The chemical structure and name are given below. Chemical name: (E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)-vinyl]-pyrimidine 4,4' methylenebis [3- hydroxy-2-naphtholate] (1:1) INDICATIONS FOR USE For the removal and control of mature infections of large strongyles_ (Strongylus vulgaris, S. edentatus, S._ _equinus); _small strongyles; pinworms_ (Oxyuris equi); _and large roundworms_ (Parascaris equorum) _in horses and ponies. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. DOSAGE AND TREATMENT Strongid Paste is to be administered as a single oral dose of 3 mg pyrantel base per lb of body weight. The syringe has 4 weight mark increments. Each weight mark indicates the recommended dose for 300 lb of body weight. DOS AGE BODY WEIGHT RANGE VOLUME MG PYRANTEL BASE ® up to 300 lb 1/4 syringe (5 mL) 900 mg 301–600 lb 1/2 syringe (10 mL) 1800 mg 601–900 lb 3/4 syringe (15 mL) 2700 mg 901–1200 lb 1 full syringe (20 mL) 3600 mg NOTE: Position screw-gauge over appropriate mark on plunger. Each mL contains 180 mg of pyrantel base as pyrantel pamoate. For maximum control of parasitism, it is recommended that foals (2–8 months of age) be dosed every 4 weeks. To minimize the potential source of infection that the mare may pose to the foal, the mare should be treated 1 month prior to anticipated foaling date Lees het volledige document