Land: Indonesië
Taal: Indonesisch
Bron: Badan Pengawas Obat dan Makanan RI - Indonesian Food and Drug Supervisory Agency
IBUPROFEN
TUNGGAL IDAMAN ABDI - Indonesia
IBUPROFEN
400 MG
TABLET SALUT SELAPUT
DUS,5 BLISTER @ 6 TABLET SALUT SELAPUT
ZAMBON S.P.A. - Italy
2021-10-29
PIL_Eng _SDF400_11_20 SPEDIFEN ® IBUPROFEN FILM-COATED TABLET CARDIOVASCULAR RISK - NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk - NSAIDs is contraindicated for the treatment of perioperative pain in the setting of coronaryartery bypass graft (CABG) surgery GASTROINTESTINAL RISK - NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomatch or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events. COMPOSITIONS SPEDIFEN 400 mg film-coated tablet, each tablet contains 400 mg Ibuprofen as L-arginine salt. SPEDIFEN 400 mg film-coated tablet also contains : Sodium hydrogen carbonat, cropovidone, magnesium stearate, Hypermellose, sucrose, Titanium dioxide and Macrogol 4000. THERAPEUTIC INDICATIONS : SPEDIFEN is indicated for relieving pain of various etiology: headache, pain after tooth extraction and postoperative pain, as well as for the treatment of primary dysmenorrhea. SPEDIFEN is also indicated for the relief of signs and symptoms of rheumatoid arthritis and _osteoarthritis_, as well as for the musculoskeletal and traumatic alterations implying pain and inflammation PHARMACOLOGICAL PROPERTIES PHARMACODYNAMIC PROPERTIES: GENERAL PROPERTIES _Pharmacotherapeutic _ _group_: Antiinflammatory and anti-rheumatic products, non-steroids, Propionic acid derivatives. ATC code: M01AE01. Ibuprofen is a synthetic analgesic-antiinflammatory drug with a marked antipyretic action. _Mechanism of action _ Ibuprofen is the first phenylpropionic acid derivative. It is a prostaglandin synthetase inhibitor with analgesic, antipyretic and anti-inflammatory properties. It possesses a non-narcotic analge Lees het volledige document