Fluimucil 600 mg Effervescent Tablet

Land: Filipijnen

Taal: Engels

Bron: FDA (Food And Drug Administration)

Werkstoffen:

Acetylcysteine

Beschikbaar vanaf:

The Cathay Drug Co., Inc.; Distributor: The Cathay Drug Co., Inc.

INN (Algemene Internationale Benaming):

Acetylcysteine

Dosering:

600 mg

farmaceutische vorm:

Effervescent Tablet

Eenheden in pakket:

Alu-alu Blister Pack x 2's (Box of 10's and 20's)

Geproduceerd door:

Zambon Switzerland Ltd., Switzerland

Autorisatie datum:

2022-10-12

Bijsluiter

FLUIMUCIL 600 MG EFFERVESCENT TABLET
(ACETYLCYSTEINE )
MUCOLYTIC
Category: Oral
DESCRIPTION
THE CATHAY DRUG CO., INC.
PRODUCT DESCRIPTION
Acetylcysteine (Fluimucil) 600 mg is a white tablet characteristic
lemon, slightly sulphureous
odour.
FORMULATION
Each tablet contains:
Acetylcysteine, Ph. Eur ………………… 600 mg
PHARMACOLOGY
Acetylcysteine, active ingredient of FLUIMUCIL, exerts an intensive
mucolytic-fluidifying action
on mucous and mucopurulent secretions by depolymerizing the
mucoproteic complexes and the
nucleic acids which confer viscosity to the vitreous and purulent
component of the sputum and
other secretions.
Furthermore, acetylcysteine exerts a direct antioxidant action, having
a free thiol (-SH) nucleophilic
group which is able to interact directly with the electrophilic group
of the oxidant radicals. Of
particular interest is the recent finding that acetylcysteine protects
α1-antitrypsin enzyme inhibiting
elastase from the inactivation by hypochlorous acid (HOCl), a powerful
oxidant agent produced by
the myeloperoxidase enzyme of activated phagocytes.
These features make ACETYLCYSTEINE (FLUIMUCIL) particularly suitable
for the treatment of
acute and chronic affections of the respiratory system, characterized
by thick, viscous mucous and
mucopurulent secretions.
In addition, due to its molecular structure, acetylcysteine can easily
cross the cellular membranes.
Inside the cell, acetylcysteine is deacetylated to L-cysteine, an
amino acid indispensable for the
glutathione synthesis (GSH).
GSH is a highly reactive tripeptide found ubiquitously in the various
tissues of animal and is
essential for the maintenance of functional capacity as well as
cellular morphological integrity. It
represents the most important protective endocellular mechanism
against oxidant radicals, either of
external or internal nature, as well as toward numerous cytotoxic
substances.
Acetylcysteine plays a role of primary importance in the maintenance
of adequate GSH levels
contributing to the cellular protection from