Land: Verenigde Staten
Taal: Engels
Bron: NLM (National Library of Medicine)
Dexamethasone Sodium Phosphate (UNII: AI9376Y64P) (Dexamethasone - UNII:7S5I7G3JQL)
MWI/VetOne
Dexamethasone Sodium Phosphate
Dexamethasone 3 mg in 1 mL
INTRAVENOUS
PRESCRIPTION
INDICATIONS AND USAGE: Dexamethasone-SP (dexamethasone sodium phosphate) is indicated as a rapid adrenal glucocorticoid and/or anti-inflammatory agent in horses. CONTRAINDICATIONS: Do not use in viral infections. Except when used for emergency therapy, dexamethasone sodium phosphate is contraindicated in animals with tuberculosis and chronic nephritis. Existence of congestive heart failure, osteoporosis and diabetes are relative contraindications. In the presence of infection appropriate antibacterial agents should also be administered and should be continued for at least 3 days after discontinuance of the hormone and disappearance of all signs of infection.
HOW SUPPLIED: Dexamethasone-SP (dexamethasone sodium phosphate) 4 mg/mL (equivalent to 3 mg/mL dexamethasone) is available in 100 mL multiple dose vials.
Abbreviated New Animal Drug Application
DEXAMETHASONE SP- DEXAMETHASONE SODIUM PHOSPHATE INJECTION, SOLUTION MWI/VETONE ---------- DEXAMETHASONE-SP (dexamethasone sodium phosphate) INJECTION USP FOR HORSES 4 MG/ML EQUIVALENT TO DEXAMETHASONE 3 MG/ML FOR INTRAVENOUS USE IN HORSES ONLY NOT FOR USE IN HUMANS KEEP OUT OF REACH OF CHILDREN WARNING: DO NOT USE IN HORSES INTENDED FOR FOOD CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: Dexamethasone sodium phosphate (a synthetic adrenocortical steroid), is a white or slightly yellow crystalline powder. It is freely soluble in water and is exceedingly hygroscopic. Each mL of Dexamethasone-SP (dexamethasone sodium phosphate) contains Dexamethasone Sodium Phosphate 4 mg (equivalent to dexamethasone 3 mg), Sodium Citrate 10 mg, Sodium Bisulfite 2 mg, Benzyl Alcohol 1.5% as a preservative, in Water for Injection q.s. Sodium Hydroxide and/or Hydrochloric Acid to adjust pH to between 7.0 and 8.5. CLINICAL PHARMACOLOGY: Dexamethasone is a synthetic corticosteriod and possesses glucocorticoid activity. Dexamethasone sodium phosphate is a salt of dexamethasone that is particularly suitable for intravenous administration because it is highly water soluble, permitting administration of relatively large doses in a small volume of diluent. Dexamethasone, as a steroid, is equivalent in potency to some established steroids while being considerably more potent than others. In the case of the dog, dexamethasone is found to be about equivalent in dosage to prednisone but about 30 to 40 times more potent than prednisolone. INDICATIONS AND USAGE: Dexamethasone-SP (dexamethasone sodium phosphate) is indicated as a rapid adrenal glucocorticoid and/or anti-inflammatory agent in horses. CONTRAINDICATIONS: Do not use in viral infections. Except when used for emergency therapy, dexamethasone sodium phosphate is contraindicated in animals with tuberculosis and chronic nephritis. Existence of congestive heart failure, osteoporosis and diabetes are relative contraindications. In Lees het volledige document