cortisone acetate- Cortisone Acetate tablet

Land: Verenigde Staten

Taal: Engels

Bron: NLM (National Library of Medicine)

Werkstoffen:

Cortisone Acetate (UNII: 883WKN7W8X) (Cortisone - UNII:V27W9254FZ)

Beschikbaar vanaf:

Pharmacia and Upjohn Company

INN (Algemene Internationale Benaming):

Cortisone Acetate

farmaceutische vorm:

TABLET

Samenstelling:

5 mg

Toedieningsweg:

ORAL

Prescription-type:

PRESCRIPTION DRUG

therapeutische indicaties:

- Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance) - Congenital adrenal hyperplasia - Hypercalcemia associated with cancer - Nonsuppurative thyroiditis As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: - Psoriatic arthritis - Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy) - Ankylosing spondylitis - Post-traumatic osteoarthritis - Acute and subacute bursitis - Synovitis of osteoarthritis - Acute nonspecific tenosynovitis - Epicondylitis - Acute gouty arthritis During an exacerbation or as maintenance therapy in selected cases of: - Systemic lupus erythematosus - Acute rheumatic carditis - Systemic dermatomyositis (polymyositis) - Pemphigus - Exfoliative dermatitis -

Product samenvatting:

Cortisone Acetate Tablets, USP are available in the following strengths and package sizes: 5 mg (white, round, scored, imprinted UPJOHN 15)         Bottles of 50                NDC 0009-0015-01 10 mg (white, round, scored, imprinted UPJOHN 23)         Bottles of 100              NDC 0009-0023-01 Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP].

Productkenmerken

CORTISONE ACETATE- CORTISONE ACETATE TABLET
PHARMACIA AND UPJOHN COMPANY
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CORTISONE ACETATE TABLETS, USP
DESCRIPTION
Cortisone acetate is a glucocorticoid. Glucocorticoids are
adrenocortical steroids, both naturally
occurring and synthetic, which are readily absorbed from the
gastrointestinal tract. Cortisone acetate is
a white to practically white, odorless, crystalline powder. It is
insoluble in water; freely soluble in
chloroform; soluble in dioxane; sparingly soluble in acetone; slightly
soluble in alcohol.
The chemical name for cortisone acetate is pregn-4-ene-3,11,20-trione,
21-(acetyloxy)-17-hydroxy and
the molecular weight is 402.49. The structural formula is represented
below:
Cortisone Acetate Tablets are available in 2 strengths: 5 mg or 10 mg.
Inactive ingredients: calcium
stearate, corn starch, lactose, mineral oil, sorbic acid, sucrose.
ACTIONS
Naturally occurring glucocorticoids (hydrocortisone and cortisone),
which also have salt-retaining
properties, are used as replacement therapy in adrenocortical
deficiency states. Their synthetic analogs
are primarily used for their potent anti-inflammatory effects in
disorders of many organ systems.
Glucocorticoids cause profound and varied metabolic effects. In
addition, they modify the body's
immune responses to diverse stimuli.
INDICATIONS AND USAGE
1. ENDOCRINE DISORDERS
Primary or secondary adrenocortical insufficiency (hydrocortisone or
cortisone is the first choice;
synthetic analogs may be used in conjunction with mineralocorticoids
where applicable; in infancy
mineralocorticoid supplementation is of particular importance)
Congenital adrenal hyperplasia
Hypercalcemia associated with cancer
Nonsuppurative thyroiditis
2. RHEUMATIC DISORDERS
As adjunctive therapy for short-term administration (to tide the
patient over an acute episode or
exacerbation) in:
Psoriatic arthritis
Rheumatoid arthritis, including juvenile rheumatoid arthritis
(selected cases may require low-dose
maintenance therapy)
Ankylosing spondylitis
Post-traumatic osteoarthriti