AMINOSYN isoleucine lysine acetate methionine phenylalanine threonine tryptophan valine arginine histidine proline serine tyrosi

Land: Verenigde Staten

Taal: Engels

Bron: NLM (National Library of Medicine)

Werkstoffen:

ISOLEUCINE (UNII: 04Y7590D77) (ISOLEUCINE - UNII:04Y7590D77)

Beschikbaar vanaf:

Hospira, Inc.

INN (Algemene Internationale Benaming):

ISOLEUCINE

Samenstelling:

ISOLEUCINE 620 mg in 100 mL

Prescription-type:

PRESCRIPTION DRUG

Autorisatie-status:

New Drug Application

Productkenmerken

AMINOSYN- ISOLEUCINE, LEUCINE, LYSINE ACETATE, METHIONINE,
PHENYLALANINE, THREONINE,
TRYPTOPHAN, VALINE, ALANINE, ARGININE, HISTIDINE, PROLINE, SERINE,
TYROSINE, AND GLYCINE INJECTION,
SOLUTION
HOSPIRA, INC.
----------
AMINOSYN
SULFITE-FREE
_A CRYSTALLINE AMINO ACID SOLUTION_
Flexible Plastic Container
R only
DESCRIPTION
Aminosyn , Sulfite-Free, (a crystalline amino acid solution) is a
sterile, nonpyrogenic solution for
intravenous infusion. Aminosyn is oxygen sensitive. Five different
formulations are available:
AMINOSYN FORMULATIONS
ESSENTIAL AMINO ACIDS (MG/100 ML)
AMINOS YN
3.5%
5%
7%
8.5%
10%
Isoleucine
252
360
510
620
720
Leucine
329
470
660
810
940
Lysine (acetate)*
252
360
510
624
720
Methionine
140
200
280
340
400
Phenylalanine
154
220
310
380
440
Threonine
182
260
370
460
520
Tryptophan
56
80
120
150
160
Valine
280
400
560
680
800
* Amount cited is for Lysine alone and does not include the acetate
salt.
NONESSENTIAL AMINO ACIDS (MG/100 ML)
AMINOS YN
3.5%
5%
7%
8.5%
10%
Alanine
448
640
900
1100
1280
Arginine
343
490
690
850
980
Histidine
105
150
210
260
300
Proline
300
430
610
750
860
Serine
147
210
300
370
420
Tyrosine
31
44
44
44
44
Glycine
448
640
900
1100
1280
ELECTROLYTES (MEQ/LITER)
AMINOS YN
3.5%
5%
7%
8.5%
10%
Sodium (Na )
None
None
None
None
None
Potassium (K )
None
None
None
None
None
Chloride (Cl
)
None
None
None
35
None
Acetate (C H O )
51
86
105
90
147
Includes chloride from HCl added for processing and pH adjustment.
Includes acetate from acetic acid used in processing and from Lysine
acetate.
®
x
®
+
+
–
a
2
3
2
– b
a
b
PRODUCT CHARACTERISTICS
AMINOS YN
3.5%
5%
7%
8.5%
10%
Protein Equivalent
(approx. grams/liter)
35
50
70
85
100
Total Nitrogen
(grams/liter)
5.5
7.86
11.00
13.4
15.72
Osmolarity
(mOsmol/liter)
322
462
655
802
932
pH
5.2
5.2
5.2
5.2
5.2
Range
(4.5 – 6.0 )(4.5 – 6.0 )(4.5 – 6.0 )(4.5 – 6.0 ) (4.5 – 6.0
)
Adjusted with acetic acid.
Adjusted with acetic acid and hydrochloric acid.
The formulas for the individual amino acids present in Aminosyn are as
follows:
ESS