喜革脈錠５毫克

Land: Taiwan

Taal: Chinees

Bron: 衛生福利部食品藥物管理署 (Ministry of Health and Welfare, Food And Drug Administration)

Werkstoffen:

NICORANDIL

Beschikbaar vanaf:

台灣中外製藥股份有限公司 台北市松山區敦化北路260號3樓 (23060795)

ATC-code:

C01DX16

farmaceutische vorm:

錠劑

Samenstelling:

NICORANDIL (2412003400) MG

Eenheden in pakket:

盒裝

klasse:

製　劑

Prescription-type:

須由醫師處方使用

Geproduceerd door:

CHUGAI PHARMACEUTICAL CO., LTD. 5-1, UKIMA 5-CHOME, KITA-KU, TOKYO, JAPAN JP

Therapeutisch gebied:

nicorandil

therapeutische indicaties:

狹心症

Product samenvatting:

有效日期: 2025/07/17; 英文品名: SIGMART TABLETS 5MG

Autorisatie datum:

2020-04-09

Bijsluiter

®
5
Nicorandil
(
: 13)
®
(SIGMART
®
Tablets)
5mg
020991
25
PDE 5(phosphodiesterase type 5)
(sildenafil
c i t r a t e
Vi a g r a
®
v a r d e n a f i l
hydrochloride trihydrate
Levitra
®
tadalafil
CIALIS
®
)
GC(guanylate cyclase)
(riociguat)
Sigmart
®
(
3.
)
SIGMART
®
5mg
(
1
)
Nicorandil 5mg
Carboxymethylcellulose Calcium, Corn Starch,
Calcium stearate, Stearyl alcohol, D-mannitol
(
)
=5mm
2 mm
C-21F
.
5
50mg
Nicorandil
15mg
3
1.
(1)
[
]
(2)
[
]
(3) 5.
(4)
NYHA III
IV
2.
(1 )
( 2 )
P D E 5
s i l d e n a f i l
citrate
Viagra
®
vardenafil
hydrochloride trihydrate
Levitra
®
tadalafil
Cialis
®
GC
(riociguat)
PDE 5
GC
(riociguat)
PDE 5
GC (riociguat)
(3 )
( 4 )
(
)
(filling pressure)
(cardiac decompensation)
(5 )
G6PD ( glucose 6
phosphate dehydrogenase)
(nitrate)
SIGMART
®
Tablets 5mg
Chugai Pharmaceutical Co., Ltd.
5-1, Ukima 5-chome, Kita-ku, Tokyo,
Japan
NIPRO PHARMA CORPORATION
KAGAMIISHI PLANT
428, Okanouchi, Kagamiishi-machi, Iwase-gun,
Fukushima, Japan
260
3
Nicorandil
13,14 )
(4)
1) Nicorandil
8,9,15 )
2)
6
SIGMART
®
(5mg
Nicorandil)
pressure-rate product
12 )
2.
N i c o r a n d i l
Nicorandil
guanylate cyclase
cyclic-GMP
Nitrates
Nitrites
in vitro
Nicorandil
Nicorandil
JAN
N-(2-hydroxyethyl)nicotinamide
nitrateester
C
8
H
9
N
3
O
4
211.17
92
6~1,000
1)
,
(
)
(1981)
2)
,
(
)
(1983)
3)
,
(
)
(1991)
4)
, 59
2079(1982)
5)
, 13
311(1982)
6) Yamada, A. et al.
Arzneim.Forsch. (Drug Res.),
371252(1987)
7) Nakagawa, Y. et al.
Jpn. Heart J., 20
881(1979)
8) Uchida, Y. et al.
Jpn. Heart J., 19
112(1978)
9)
,
, 12371(1980)
10)
Mizukami, M. et al.
Arzneim. Forsch.
Drug
Res.
,311244(1981)
11)
, 15
385(1978)
12)
, Therapeutic Research, 13(5)
1823(1992)
13) Uchida, Y. et al.
Jpn. Heart J., 19
904(1978)
14) Sakai, K. et al.
J. Pharmacol. Exp. Ther.,227
220(1983)
15) Sakai, K. et al.
J. Cardiovasc. Pharmacol., 3
139(1981)
260
3
TEL [phone]
: JPI Feb 2020 ( version 15)
(1)
(4)
1.
5
SIGMART
®
5mg
2
(10mg Nicorandil)
Nicorandil
1 )
SIGMART
®
(
)
AUC
0-4
( hr
.
ng/mL )
C
max
( ng/mL )
T
max
( hr )
t
1/2
( hr