Tranylcypromine 10mg tablets

Land: Storbritannia

Språk: engelsk

Kilde: MHRA (Medicines & Healthcare Products Regulatory Agency)

Aktiv ingrediens:

Tranylcypromine sulfate

Tilgjengelig fra:

CST Pharma Ltd

ATC-kode:

N06AF04

INN (International Name):

Tranylcypromine sulfate

Dosering :

10mg

Legemiddelform:

Oral tablet

Administreringsrute:

Oral

Klasse:

No Controlled Drug Status

Resept typen:

Valid as a prescribable product

Produkt oppsummering:

BNF: 04030200; GTIN: 5055946807287

Informasjon til brukeren

TRANYLCYPROMINE 10MG TABLETS
CHILDREN AND ADOLESCENTS
Tranylcypromine 10mg tablets is not recommended for children under 18
years old (see section 3 ‘Use in children and adolescents’).
OTHER MEDICINES AND TRANYLCYPROMINE 10MG TABLETS
Please tell your doctor or pharmacist if you are taking, have recently
taken
or might take any other medicines, including medicines obtained
without a
prescription.
DO NOT TAKE TRANYLCYPROMINE 10MG TABLETS WITH THE FOLLOWING
MEDICINES:
*
medicines called sympathomimetic agents - these include ephedrine,
pseudoephedrine, adrenaline and noradrenaline (these may be found in
medicines used to treat heart problems and asthma as well as some
decongestants and cough/cold remedies)
*
bupropion, a medicine to help you stop smoking
*
medicines to control appetite, e.g. amphetamine and fenfluramine
*
medicines that treat Parkinson’s disease, e.g. levodopa
*
dopamine, a medicine used to treat certain heart conditions
*
the pain killers pethidine and nefopam
*
general anaesthetics such as propofol, which are used in surgery
*
other medicines used to treat depression (e.g. amitriptyline,
imipramine,
tryptophan)
*
buspirone, used to treat anxiety.
TRANYLCYPROMINE MUST BE TAKEN WITH CAUTION IF YOU ARE TAKING THE
FOLLOWING MEDICINES:
*
other MAOIs such as isocarboxazid
*
strong pain killers e.g. codeine
*
medicines to treat seizures/fits, e.g. carbamazepine
*
barbiturates used to treat severe sleeping problems, e.g.
amylobarbitone
*
SSRIs such as fluoxetine or sertraline (for depression). Taking your
medicine with these products may cause the following serious side
effects:
sweating, extreme agitation, confusion, muscle stiffness
*
medicines for high blood pressure (e.g. guanethidine, reserpine,
methyldopa)
*
medicines to treat diabetes (e.g. insulin, metformin)
*
antihistamines used to treat allergies, e.g. cetirizine.
Consult your doctor before you take Tranylcypromine if you are taking
or
might be taking any of these.
TAKING TRANYLCYPROMINE 10MG TABLETS WITH FOOD, DRINK AND ALCOHOL
You shoul

Preparatomtale

SUMMARY OF PRODUCT CHARACTERISTICS
1
NAME OF THE MEDICINAL PRODUCT
Parnate 10mg Tablets
Tranylcypromine 10mg Tablets
2
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each tablet contains tranylcypromine sulfate equivalent to 10mg of
tranylcypromine base.
Excipients with known effect:
3.2mg of Ponceau 4R (E124) and 55.04mg of sucrose per tablet
For the full list of excipients, see section 6.1.
3
PHARMACEUTICAL FORM
Coated tablet.
Geranium red coloured, bi-convex, sugar-coated tablets.
4
CLINICAL PARTICULARS
4.1
THERAPEUTIC INDICATIONS
Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor for the
treatment
of
symptoms
of
depressive
illness
especially
where
phobic
symptoms are present or where treatment with other types of
anti-depressants
has failed. It is not recommended for mild depressive states resulting
from
temporary situational difficulties.
4.2
POSOLOGY AND METHOD OF ADMINISTRATION
Posology
ADULTS
Initially, 1 tablet morning and afternoon. If the response is not
adequate after
the first week add a further tablet at midday, and continue for at
least a week.
A dosage of 3 tablets a day should only be exceeded with caution. When
a
satisfactory
response
has
been
obtained,
dosage
may
be
reduced
to
maintenance level often of 1 tablet a day.
When given with a tranquillizer, the dosage of `parnate' is not
affected when
given concurrently with electroconvulsive therapy; the usual dosage is
1 tablet
twice a day during the series and 1 tablet a day afterwards as
maintenance
therapy.
Elderly:
Use with great caution and at a lower dosage.
_Paediatric population _
Tranylcypromine is not indicated for children under 18 years of age.
Method of administration
Tranylcypromine 10mg Tablets/ Parnate 10mg Tablets are for oral
administration only. Tablets should be swallowed whole with a glass of
water.
4.3 CONTRAINDICATIONS
Hypersensitivity to the active substance or to any of the excipients
listed in
section 6.1.
Do not give tranylcypromine until at least two weeks after stopping
treatment
with other MAOIs.
Allow
3
weeks
to