Hytrin

Land: New Zealand

Språk: engelsk

Kilde: Medsafe (Medicines Safety Authority)

Aktiv ingrediens:

Terazosin hydrochloride dihydrate 1.187mg equivalent to 1 mgTerazosin;  ; Terazosin hydrochloride dihydrate 2.347mg equivalent to 2 mg Terazosin; Terazosin hydrochloride dihydrate 5.935mg equivalent to 5 mg Terazosin

Tilgjengelig fra:

BGP Products

INN (International Name):

Terazosin hydrochloride dihydrate 1.187 mg (=1 mgTerazosin)

Legemiddelform:

Tablet

Sammensetning:

Active: Terazosin hydrochloride dihydrate 1.187mg equivalent to 1 mgTerazosin   Excipient: Lactose monohydrate Magnesium stearate Maize starch Purified talc Starch Active: Terazosin hydrochloride dihydrate 2.347mg equivalent to 2 mg Terazosin Excipient: Lactose monohydrate Magnesium stearate   Maize starch Quinoline yellow Starch Active: Terazosin hydrochloride dihydrate 5.935mg equivalent to 5 mg Terazosin Excipient: Iron oxide red Lactose monohydrate Magnesium stearate Maize starch Purified talc Starch

Enheter i pakken:

Blister pack, 7x1mg +14x2mg + 7x5mg, 28 tablets

Klasse:

Prescription

Resept typen:

Prescription

Produsert av:

Abbott Ireland Pharmaceutical Operations

Produkt oppsummering:

Package - Contents - Shelf Life: Blister pack, 7x1mg +14x2mg + 7x5mg - 28 tablets - 60 months from date of manufacture stored at or below 25°C

Autorisasjon dato:

2000-05-22

Preparatomtale

Hytrin Datasheet 
14 April 2010 
Page 1 of 13 
Version 04 

DATA SHEET 
HYTRIN 
HYTRIN (TERAZOSIN MONOHYDROCHLORIDE DIHYDRATE) TABLETS 1 MG, 2 MG, 5
MG 

PRESENTATION 
Terazosin hydrochloride tablets are round, flat with bevelled edges,
7.1 mm in 
diameter and embossed with the Abbott logo. Hytrin tablets are
available as follows: 
1 mg white tablet; 2 mg pale yellow tablet; 5 mg tan tablet. 
Please note: These tablets are not capable of providing a divided
dose. Do not halve 
the tablets. 
USES 
ACTIONS 
Hytrin (terazosin hydrochloride) for benign prostatic hyperplasia, is
an alpha-1-
selective adrenoceptor blocking agent. 
Studies suggest that alpha-1-adrenoceptor blockade is useful in
improving the 
urodynamics in patients with chronic bladder outlet obstruction, such
as in Benign 
Prostatic Hyperplasia (BPH). 
The symptoms of BPH are caused mainly by the presence of an enlarged
prostate and 
by the increased smooth muscle tone of the bladder outlet and the
prostate, which is 
regulated by alpha-1-adrenergic receptors. 
In in vitro experiments, terazosin has been shown to antagonize
phenylephrine-
induced contractions in human prostatic tissue. In clinical trials
terazosin has been 
shown to improve the urodynamics and symptomatology in patients with
BPH. 
Terazosin also decreases blood pressure gradually within 15 minutes
following oral 
administration. 
The systolic and diastolic blood pressures are lowered in both the
supine and standing 
positions. The effect is most pronounced on the diastolic blood
pressure. These 
changes are usually not accompanied by reflex tachycardia. A greater
blood pressure 
effect associated with peak plasma concentrations (first few hours
after dosing) 
appears somewhat more position-dependent (greater in the erect
position) than the  
effect of terazosin at 24 hours, and in the erect position there
is also a 6-10 beat per 
minute increase in heart rate in the first few hours after dosing. 
Hytrin Datash