Valium

Country: Awstralja

Lingwa: Ingliż

Sors: Department of Health (Therapeutic Goods Administration)

Ingredjent attiv:

Diazepam

Disponibbli minn:

Roche Products Pty Ltd

Klassi:

Medicine Registered

Fuljett ta 'informazzjoni

VALIUM
®

PRONOUNCED (VAL-I-UM)
_contains the active ingredient diazepam_
CONSUMER MEDICINE INFORMATION

WHAT IS IN THIS LEAFLET
This leaflet answers some common
questions about VALIUM.
It does not contain all the available
information.
It does not take the place of talking to
your doctor or pharmacist.
All medicines have risks and
benefits. Your doctor has weighed
the risks of you taking VALIUM
against the benefits they expect it
will have for you.
IF YOU HAVE ANY CONCERNS ABOUT
TAKING THIS MEDICINE, ASK YOUR
DOCTOR OR PHARMACIST.
KEEP THIS LEAFLET WITH THE MEDICINE.
You may need to read it again.
WHAT VALIUM IS USED
FOR
VALIUM is used for anxiety.
Anxiety or tension associated with
the normal stress of everyday life
usually does not require treatment
with medicines.
VALIUM is used to relax muscles.
VALIUM can also be used to treat
trembling, confusional states or
anxiety associated with alcohol
withdrawal. It is also used to treat
panic attacks.
VALIUM belongs to a group of
medicines called benzodiazepines.
They are thought to work by their
action on brain chemicals.
Benzodiazepines are not
recommended as the only treatment
of severe mental illnesses and should
not be used alone to treat depression.
Your doctor, however, may have
prescribed VALIUM for another
purpose.
ASK YOUR DOCTOR IF YOU HAVE ANY
QUESTIONS ABOUT WHY VALIUM HAS
BEEN PRESCRIBED FOR YOU.
In general, benzodiazepines such as
VALIUM should be taken for short
periods only (around 2 to 4 weeks).
Continuous long term use is not
recommended unless advised by your
doctor.
THE USE OF BENZODIAZEPINES MAY
LEAD TO DEPENDENCE ON THE
MEDICINE.
This medicine is available only with
a doctor's prescription.
BEFORE YOU TAKE
VALIUM
_DO NOT TAKE VALIUM IF:_
1. YOU HAVE HAD AN ALLERGIC
REACTION TO VALIUM, ANY OTHER
BENZODIAZEPINE MEDICINE OR ANY
INGREDIENTS LISTED AT THE END OF
THIS LEAFLET
2. YOU HAVE SEVERE AND CHRONIC
LUNG DISEASE
3. YOU HAVE SEVERE LIVER DISEASE
4. YOU HAVE TEMPORARY STOPS IN
BREATHING DURING SLEEP
5. YOU SUFFER FROM SEVERE

Karatteristiċi tal-prodott

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VALIUM
® 
PI121017 
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CDS 7.0 

NAME OF THE MEDICINE 

VALIUM


(_diazepam_) 

CAS Registry Number: 439-14-5 

DESCRIPTION 

VALIUM  (diazepam)  is  a  benzodiazepine  derivative  developed  through  original  Roche  research.  
Chemically, diazepam is 7 - chloro - 1,3 - dihydro - 1 - methyl - 5 - phenyl - 2H - 1,4 - benzodiazepin - 
2  -  one.    It  is  a  colourless  crystalline  compound,  insoluble  in  water  and  has  a  molecular  weight  of 
284.74. 

Each  2  mg  VALIUM  tablet  contains  the  following  excipients:    lactose,  maize  starch,  magnesium 
stearate. 

Each 5 mg VALIUM tablet contains the following excipients:  lactose monohydrate, maize starch, iron 
oxide yellow CI77492, magnesium stearate. 

PHARMACOLOGY 

PHARMACODYNAMICS 

_Mechanism of Action _
Diazepam  is  a  member  of  the  group  of  classical  benzodiazepines  and  exhibits  anxiolytic,  sedative, 
muscle relaxant and anti-convulsant effects.  This is presumed to be the result of facilitating the action 
in the brain of gamma-aminobutyric acid, a naturally occurring inhibitory transmitter. 

PHARMACOKINETICS 

_Absorption and Bioavailability _
After oral administration, diazepam is rapidly and completely absorbed from the gastrointestinal tract, 
with peak plasma concentrations appearing 30 - 90 minutes after oral intake.  The speed of onset after 
intramuscular (IM) administration is variable, depending on the muscle mass used and other factors.    

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VALIUM
® 
PI121017 
2 of 11 
CDS 7.0 

_Distribution _
Diazepam is 98% protein-bound in the plasma, and is excreted in the urine mainly in the form of free 
or conjugated metabolites.  VALIUM and its metabolites