Country: Awstralja
Lingwa: Ingliż
Sors: Department of Health (Therapeutic Goods Administration)
hydrochlorothiazide,telmisartan
Amneal Pharma Australia Pty Ltd
Hydrochlorothiazide,Telmisartan
Registered
_Telmisartan HCTZ AN tablets – Consumer Medicine Information _ _ _ _Telmisartan HCTZ AN CMI v2.0 _ _ _ _ _ _Page 1 _ TELMISARTAN HCTZ AN TABLETS _ _ _TELMISARTAN AND HYDROCHLOROTHIAZIDE _ CONSUMER MEDICINE INFORMATION WHAT IS IN THIS LEAFLET This leaflet answers some common questions about TELMISARTAN HCTZ AN. It does not contain all available information. It does not take the place of talking to your doctor or pharmacist. This leaflet was last updated on the date at the end of this leaflet. More recent information may be available. The latest Consumer Medicine Information is available from your pharmacist, doctor, or from www.medicines.org.au and may contain important information about the medicine and its use of which you should be aware. All medicines have benefits and risks. Your doctor has weighed the risks of you taking this medicine against the benefits it is expected to have for you. IF YOU HAVE ANY CONCERNS ABOUT THIS MEDICINE, ASK YOUR DOCTOR OR PHARMACIST. KEEP THIS LEAFLET WITH THE MEDICINE. You may need to read it again. WHAT TELMISARTAN HCTZ AN IS USED FOR TELMISARTAN HCTZ AN is used to lower high blood pressure (hypertension). Everyone has blood pressure. This pressure helps your blood move around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm or relaxed. There are usually no signs of hypertension. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. If high blood pressure is not treated, it can lead to serious health problems, including stroke, heart disease and kidney failure. _HOW TELMISARTAN HCTZ AN WORKS _ _ _ TELMISARTAN HCTZ AN contains telmisartan and hydrochlorothiazide in one single tablet. These two active ingredients help to reduce blood pressure in different ways: Telmisartan belongs to a group of medicines called angiotensin II rec Aqra d-dokument sħiħ
Telmisartan HCTZ AN PI v3.0 Page 1 TELMISARTAN HCTZ AN TABLETS (TELMISARTAN AND HYDROCHLOROTHIAZIDE) NAME OF THE MEDICINE TELMISARTAN HCTZ AN contains the active ingredients telmisartan and hydrochlorothiazide. TELMISARTAN HCTZ AN is available in three tablet strengths: TELMISARTAN HCTZ AN 40/12.5 containing telmisartan 40 mg/hydrochlorothiazide 12.5 mg, TELMISARTAN HCTZ AN 80/12.5 containing telmisartan 80 mg/hydrochlorothiazide 12.5 mg, and TELMISARTAN HCTZ AN 80/25 containing telmisartan 80 mg/hydrochlorothiazide 25 mg. Telmisartan and hydrochlorothiazide have the following structural formula: TELMISARTAN HYDROCHLOROTHIAZIDE DESCRIPTION Telmisartan is a specific angiotensin II receptor (type AT 1 ) antagonist. The chemical name for telmisartan is 4’-[(1,4’-dimethyl-2’-propyl[2,6’-bi-1_H_-benzimidazol]-1’-yl)-methyl]-[1,1’-biphenyl]-2- carboxylic acid (IUPAC nomenclature). The molecular formula is C 33 H 30 N 4 O 2 and the molecular weight is 514.6. The CAS number is 144701-48-4. Telmisartan is an off-white to yellowish crystalline powder. It is practically insoluble in water, very slightly soluble in ethanol, slightly soluble in methanol and soluble in a mixture of chloroform and methanol (1:1). Hydrochlorothiazide is a benzothiadiazine (thiazide) diuretic. The chemical name for hydrochlorothiazide is 6-chloro-3,4-dihydro-2_H_-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. The molecular formula is C 7 H 8 ClN 3 O 4 S 2 and the molecular weight is 297.73. The CAS number is 58-93-5. Hydrochlorothiazide is a white, or practically white, odourless crystalline powder. It is very slightly soluble in water, and freely soluble in sodium hydroxide solution. TELMISARTAN HCTZ AN tablets contain a combination of 40 mg of telmisartan and 12.5 mg of hydrochlorothiazide or 80 mg of telmisartan and 12.5 mg or 25 mg of hydrochlorothiazide. The excipients in each tablet are povidone (K25), lactose, magnesium stearate, meglumine, sodium Telmisartan HCTZ AN PI v3.0 Page 2 hydroxide, sodium stearyl fumar Aqra d-dokument sħiħ