PMS-VANCOMYCIN 1 G POWDER FOR SOLUTION

Country: Kanada

Lingwa: Ingliż

Sors: Health Canada

Ingredjent attiv:

VANCOMYCIN (VANCOMYCIN HYDROCHLORIDE)

Disponibbli minn:

PHARMASCIENCE INC

Kodiċi ATC:

J01XA01

INN (Isem Internazzjonali):

VANCOMYCIN

Dożaġġ:

1G

Għamla farmaċewtika:

POWDER FOR SOLUTION

Kompożizzjoni:

VANCOMYCIN (VANCOMYCIN HYDROCHLORIDE) 1G

Rotta amministrattiva:

INTRAVENOUS

Unitajiet fil-pakkett:

20ML

Tip ta 'preskrizzjoni:

Prescription

Żona terapewtika:

GLYCOPEPTIDES

Sommarju tal-prodott:

Active ingredient group (AIG) number: 0131315009; AHFS:

L-istatus ta 'awtorizzazzjoni:

APPROVED

Data ta 'l-awtorizzazzjoni:

2000-03-14

Karatteristiċi tal-prodott

PRODUCT MONOGRAPH
INCLUDING PATIENT MEDICATION INFORMATION
PR
PMS-VANCOMYCIN
Vancomycin Hydrochloride for Injection USP
0.5g and 1g Vancomycin per Vial Sterile Lyophilized
Powder for Injection
ANTIBIOTIC
PHARMASCIENCE INC.
Date of Revision:
6111 Royalmount Ave, Suite #100
March 8, 2018
Montréal, Québec
H4P 2T4
www.pharmascience.com
Control No. 213062
_pms-VANCOMYCIN Product Monograph _
_Page 2 of 30_
PRODUCT MONOGRAPH
NAME OF DRUG
PR
PMS-VANCOMYCIN
Vancomycin Hydrochloride for Injection USP
0.5g and 1g Vancomycin per Vial Sterile Lyophilized Powder for
Injection
THERAPEUTIC CLASSIFICATION
Antibiotic
ACTION
The inhibition of cell wall synthesis has been shown by _in vitro_
studies to be responsible for the
bactericidal action of vancomycin against many gram-positive bacteria.
There is also evidence that
RNA synthesis is selectively inhibited and the permeability of the
cell membrane is altered by
vancomycin.
INDICATIONS AND CLINICAL USE
pms-VANCOMYCIN is indicated in the therapy of severe or
life-threatening staphylococcal
infections in patients who cannot receive or have failed to respond to
the penicillins
or
cephalosporins or who have infections with staphylococci resistant to
other antibiotics, including
methicillin.
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of pms-
VANCOMYCIN and other antibacterial drugs, pms-VANCOMYCIN should be
used only to treat
infections that are proven or strongly suspected to be caused by
susceptible bacteria. When culture
and susceptibility information are available, they should be
considered in selecting or modifying
antibacterial therapy. In the absence of such data, local epidemiology
and susceptibility patterns
may contribute to the empiric selection of therapy.
In the treatment of staphylococcal endocarditis, vancomycin has been
used successfully alone.
In other infections due to staphylococci, including osteomyelitis,
pneumonia, septicemia, and soft-
tissue infections, vancomycin's effectiveness
has been documented. Antibiotics
are us