Idaman Pharma Penicillin V Tablet 125mg

Country: Malasja

Lingwa: Ingliż

Sors: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Ingredjent attiv:

PHENOXYMETHYLPENICILLIN POTASSIUM

Disponibbli minn:

IDAMAN PHARMA MANUFACTURING SDN. BHD.

INN (Isem Internazzjonali):

PHENOXYMETHYLPENICILLIN POTASSIUM

Unitajiet fil-pakkett:

50 Tablets; 50 Tablets

Manifatturat minn:

IDAMAN PHARMA MANUFACTURING SDN. BHD.

Fuljett ta 'informazzjoni

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
IDAMAN PHARMA PENICILLIN V TABLET
Phenoxymethylpenicillin (125mg)
1
WHAT IS IN THIS LEAFLET
1.
What PENICILLIN V TABLET is
used for
2.
How PENICILLIN V TABLET
works
3.
Before you use PENICILLIN V
TABLET
4.
How
to
use
PENICILLIN
V
TABLET
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
PENICILLIN V TABLET
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT PENICILLIN V TABLET IS
USED FOR
This medicine can be used to treat the
infections of the:
•
nose, throat or ear
•
lungs
•
urinary tract
Penicillin is also indicated for prevention
of
rheumatic
fever
(an
inflammatory
disease which can cause damage to the
skin, joints, brain or heart) and prevention
against infection after tonsils removal and
tooth extraction
It
will
not
work
against
infections
caused by viruses, such as colds.
HOW PENICILLIN V TABLET WORKS
It is an antibiotic that belongs to a group
of
medicines
called
penicillins.
These
antibiotics work by killing the bacteria
that are causing the infection.
BEFORE
YOU
USE
PENICILLIN
V
TABLET
_-When you must not use it _
Do not take PENICILLIN V TABLET if
you have allergic reaction to: -
•
Phenoxymethylpenicillin
•
Any other penicillins
•
Any of the ingredients listed at the
end of this leaflet.
Do not take this medicine if you have
serious acute infections.
_-Before you start to use it _
Tell your doctor if you have or have had
any health problems especially kidney
impairment.
There is possibility of cross-sensitivity
with
other
beta-lactam
antibiotics.
Please tell your doctor or pharmacist if
you are required to take PENICILLIN V
TABLET
together
with
other
beta-
lactam antibiotics.
Please inform your doctor if you have
previous
history
of
hypersensitivity
reactions to penicillin, cephalosporins,
carbapenem, or beta-lactam antibiotics.
If you are not sure if any of the above
conditions
apply
to
you,
talk
to
your
doctor
or
pharmacist
before
using
PENICILLIN V TABLET
_-Taking other medic

Karatteristiċi tal-prodott

ADVERSE EFFECTS
Each tablet contains Phenoxymethylpenicillin Potassium equivalent
to 125 mg of Phenoxymethylpenicillin.
Phenoxymethylpenicillin is inactivated by penicillinase and other
beta-lactamases. Phenoxymethylpenicillin binds to penicillin binding
proteins located on the inner membrane of the bacterial cell wall.
Phenoxymethylpenicillin binds to and inactivates these proteins
resulting
in
weakening
of
the
bacterial
cell
wall
and
lysis.
Phenoxymethylpenicillin is a broad spectrum beta-lactam antibiotic
with bactericidal action against Gram-positive bacteria and Gram-
negative
cocci.
Its
antimicrobial
action
is
similar
to
that
of
benzylpenicillin. Phenoxymethylpenicillin is usually active against
the following organisms:
a) Gram-positive aerobes and anaerobes including: _ Bacillus
anthracis, _
_Clostridium perfringens, Clostridium tetani, Corynebacterium
diphtheriae, _
_Erysipelothrix rhusiopathiae, Listeria monocytogenes,
Peptostreptococcus _
_spp., Streptococcus agalactiae_ (Group B), _ Streptococcus
pneumoniae, _
_and Streptococcus pyogenes_ (Group A).
b) Gram-negative including _Neisseria meningitidis_ and _Neisseria _
_gonorrhoeae_
PHARMACOKINETICS
ABSORPTION: Phenoxymethylpenicillin is stable under acidic conditions
so it can be administered by oral route. Phenoxymethylpenicillin is
rapidly, but incompletely absorbed after oral administration and the
absorption level is around 60%. The simultaneous administration
of
food
slightly
decreases
the
peak
plasma
concentration
of
phenoxymethylpenicillin, but does not appear to affect the extent
of absorption. Peak plasma concentrations are reached in about
45 minutes. The peak plasma concentration increases approximately
in proportion with increased doses. Peak serum concentrations of
3-6 jig per ml have been seen following dosage of 250 mg to 500 mg
by mouth.
DISTRIBUTION: Phenoxymethylpenicillin is widely distributed in the
body
tissues and fluids (volume of distribution about 0.2 1 kg-1 of body
weight)
and more readily penetrates inflamed tissues. It also d