Zynomax Powder For Oral Suspension 200mg5ml

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

AZITHROMYCIN DIHYDRATE

Boleh didapati daripada:

Duopharma Marketing Sdn. Bhd.

INN (Nama Antarabangsa):

AZITHROMYCIN DIHYDRATE

Unit dalam pakej:

15 ml; 20 ml

Dikeluarkan oleh:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

Risalah maklumat

_Consumer Medication Information Leaflet (RiMUP)_
1
ZYNOMAX POWDER FOR ORAL SUSPENSION 200MG/5ML
Azithromycin 200mg/5ml
WHAT IS IN THIS LEAFLET
1.
WHAT ZYNOMAX POWDER
FOR ORAL SUSPENSION
200MG/5ML IS USED FOR
2.
HOW ZYNOMAX POWDER FOR
ORAL SUSPENSION
200MG/5ML WORKS
3.
BEFORE YOU USE ZYNOMAX
POWDER FOR ORAL
SUSPENSION 200MG/5ML
4.
HOW TO USE ZYNOMAX
POWDER FOR ORAL
SUSPENSION 200MG/5ML
5.
WHILE YOU ARE USING IT
6.
SIDE EFFECTS
7.
STORAGE AND DISPOSAL OF
ZYNOMAX POWDER FOR ORAL
SUSPENSION 200MG/5ML
8.
PRODUCT DESCRIPTION
9.
MANUFACTURER AND PRODUCT
REGISTRATION HOLDER
10.
DATE OF REVISION
1. WHAT ZYNOMAX POWDER FOR ORAL
SUSPENSION 200MG/5ML
IS USED FOR
Zynomax
Powder
For
Oral
Suspension
200mg/5ml
is
used
to
treat
infections
caused
by
certain
bacteria
and
other
micro-organisms
which include:
•
Chest,
throat,
ear
or
nasal
infections
(such
as
bronchitis,
pneumonia, tonsillitis, pharyngitis,
acute otitis media and sinusitis)
•
Skin
and
soft
tissue
infections
(such as an abscess or boil)
•
Sexually-transmitted
diseases
caused
by
organisms
called
Chlamydia or Gonorrhoea.
Zynomax
Powder
For
Oral
Suspension 200mg/5ml is also used
to prevent infections by a bacterium
called
Mycobacterium
Avium-
intracellulare
Complex
(MAC)
in
some people.
2. HOW ZYNOMAX POWDER FOR ORAL
SUSPENSION 200MG/5ML WORKS
Zynomax
Powder
For
Oral
Suspension
200mg/5ml
is
an
antibiotic, which belongs to a group
of
medicines
called
azalides.
The
azalides are a sub-class of a group of
antibiotics called macrolides.
Zynomax
Powder
For
Oral
Suspension
200mg/5ml
works
by
killing
or
stopping
the
growth
of
bacteria causing your infection.
Zynomax
Powder
For
Oral
Suspension 200mg/5ml will not work
against viral infections such as colds
or influenza.
Ask
your
doctor
if
you
have
any
questions
about
why
Zynomax
Powder
For
Oral
Suspension
200mg/5ml has been prescribed for
you.
Your
doctor
may
have
prescribed it for another reason.
Zynomax
Powder
For
Oral
Suspension
200mg/5ml
is
only
available with a doctor's prescription.
This medicine is not addictive.
3.
B

Ciri produk

A. Tablet 250mg
Azithromycin 250mg
B. Powder for Oral Suspension 200mg/5ml
Azithromycin 200mg/5ml
CLINICAL PHARMACOLOGY
Pharmacodynamic Properties
Pharmacotherapeutic group: Macrolides, ATC code J01FA.
Azithromycin is the first of a subclass of macrolide antibiotics,
known as azalides, and is chemically different from
erythromycin. Chemically it is derived by insertion of a nitrogen atom
into the lactone ring of erythromycin A. The chemical
name of azithromycin is 9-deoxy-9a-aza-9a-methyl-9a-homoerythromycin
A. The molecular weight is 749.0.
Azithromycin binds to the 23S rRNA of the 50S ribosomal subunit. It
blocks protein synthesis by inhibiting the
transpeptidation/translocation step of protein synthesis and by
inhibiting the assembly of the 50S ribosomal subunit.
Antibacterial spectrum
The susceptibility of bacterial species to azithromycin is shown
below.
The prevalence of acquired resistance may vary geographically and with
time for selected species and local information on
resistance is desirable, particularly when treating severe infections.
As necessary, expert advice should be sought when the
local prevalence of resistance is such that the utility of the agent
in at least some types of infections is questionable.
In-vitro susceptibility data do not always correlate with clinical
results.
Organisms that are commonly susceptible to azithromycin include:
Aerobic and facultative gram-positive bacteria
(erythromycin-susceptible isolates): _S. aureus, Streptococcus
agalactiae,* S. _
_pneumoniae,* Streptococcus pyogenes,_* other b-hemolytic streptococci
(Groups C, F, G) and viridans streptococci.
Macrolide-resistant isolates are encountered relatively frequently
among aerobic and facultative gram-positive bacteria, in
particular among methicillin-resistant _S. aureus_ (MRSA) and
penicillin-resistant _S. pneumoniae _(PRSP).
Aerobic and facultative gram-negative bacteria: _ Bordetella
pertussis, Haemophilus ducreyi,_*_ Haemophilus influenzae,_*
_Haemophilus parainfluenzae,_*_ Legionella pneumophila, Moraxella
cat