VETRIMEC- ivermectin injection

Country: Amerika Syarikat

Bahasa: Inggeris

Sumber: NLM (National Library of Medicine)

Bahan aktif:

IVERMECTIN (UNII: 8883YP2R6D) (IVERMECTIN - UNII:8883YP2R6D)

Boleh didapati daripada:

VetOne

INN (Nama Antarabangsa):

IVERMECTIN

Komposisi:

IVERMECTIN 10 mg in 1 mL

Laluan pentadbiran:

SUBCUTANEOUS

Jenis preskripsi:

OTC

Tanda-tanda terapeutik:

INDICATIONS Cattle:  Vetrimec 1% Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, grubs, sucking lice, and mange mites in cattle: Gastrointestinal Roundworms (adults and fourth-stage larvae): Ostertagia ostertagi (including inhibited O. ostertagi ), O. lyrata, Haemonchus placei, Trichostrongylus axei, T. colubriformis, Cooperia oncophora, C. punctata, C. pectinata, Oesophagostomum radiatum, Bunostomum phlebotomum, Nematodirus helvetianus (adults only), N. spathiger (adults only) Lungworms (adults and fourth-stage larvae): Dictyocaulus viviparus Cattle Grubs (parasitic stages): Hypoderma bovis, H. lineatum Sucking Lice: Linognathus vituli, Haematopinus eurysternus, Solenopotes capillatus Mites (scabies):  Psoroptes ovis ( syn. P. communis var. bovis), Sarcoptes scabiei var. bovis Persistent Activity Ivermectin injection has been proved to effectively control infections and to protect cattle from reinfection with Dictyocaulus viviparus and Oesophagostomum radiatum for 28 days after treatment; Ostertagia ostertagi, Trichostrongylus axei and Cooperia punctata for 21 days after treatment; Haemonchus placei and Cooperia oncophora for 14 days after treatment. Swine: Vetrimec 1% Injection is indicated for the effective treatment and control of the following harmful species of gastrointestinal roundworms, lungworms, lice, and mange mites in swine: Gastrointestinal Roundworms: Large roundworms, Ascaris suum (adults and fourth-stage larvae), Red stomach worm, Hyostrongylus rubidus (adults and fourth-stage larvae), Nodular worm, Oesophagostomum spp. (adults and fourth-stage larvae), Threadworm, Strongyloides ransomi (adults) Somatic Roundworm Larvae: Threadworm, Strongyloides ransomi (somatic larvae) Sows must be treated at least seven days before farrowing to prevent infection in piglets. Lungworms: Metastrongylus spp. (adults) Lice: Haematopinus suis Mange Mites: Sarcoptes scabiei var. suis

Ringkasan produk:

HOW SUPPLIED Vetrimec 1% Injection for Cattle and Swine is available in three ready-to-use sizes: The 250 mL plastic bottle suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 10 head of 550 lb (250 kg) cattle or 100 head of 38 lb (17.3 kg) swine. The 500 mL plastic bottle suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 100 head of 550 lb (250 kg) cattle or 1000 head of 38 lb (17.3 kg) swine. The 1000 mL plastic bottle suitable for use with automatic syringe equipment. Each bottle contains sufficient solution to treat 200 head of 550 lb (250 kg) cattle or 2000 head of 38 lb (17.3 kg) swine.

Status kebenaran:

New Animal Drug Application

Ciri produk

VETRIMEC- IVERMECTIN INJECTION
VETONE
----------
VETRIMEC 1%
(IVERMECTIN)
Injection for Cattle and Swine
1% STERILE SOLUTION
A PARASITICIDE FOR THE TREATMENT AND CONTROL OF INTERNAL AND EXTERNAL
PARASITES OF CATTLE AND SWINE.
CONSULT YOUR VETERINARIAN FOR ASSISTANCE IN THE DIAGNOSIS, TREATMENT,
AND
CONTROL OF PARASITISM.
INTRODUCTION
Vetrimec 1% (ivermectin) is an injectable parasiticide for cattle and
swine. One low-
volume dose effectively treats and controls the following internal and
external parasites
that may impair the health of cattle and swine: gastrointestinal
roundworms (including
inhibited _Ostertagia ostertagi_ in cattle), lungworms, grubs, sucking
lice, and mange mites
of cattle; and gastrointestinal roundworms, lungworms, lice, and mange
mites of swine.
PRODUCT DESCRIPTION
Ivermectin is derived from the avermectins, a family of potent,
broadspectrum
antiparasitic agents isolated from fermentation of _Streptomyces
avermitilis_.
Vetrimec 1% Injection is a clear, ready-to-use, sterile solution
containing 1% ivermectin,
40% glycerol formal, and propylene glycol, q.s. ad 100%. Vetrimec 1%
Injection is
formulated to deliver the recommended dose level of 200 mcg
ivermectin/kilogram of
body weight in cattle when given subcutaneously at the rate of 1
mL/110lb (50kg). In
Swine, Vetrimec 1% Injection is formulated to deliver the recommended
dose level of
300 mcg ivermectin/kilogram body weight when given subcutaneously in
the neck at the
rate of 1 mL per 75lb (33kg).
MODE OF ACTION
Ivermectin is a member of the macrocyclic lactone class of
endectocides which have a
unique mode of action. Compounds of the class bind selectively and
with high affinity to
glutamate-gated chloride ion channels which occur in invertebrate
nerve and muscle
cells. This leads to an increase in the permeability of the cell
membrane to chloride ions
with hyperpolarization of the nerve or muscle cell, resulting in
paralysis and death of the
parasite. Compounds of this class may also interact with other
ligand-gated chloride
channels, su