VERAPAMIL HYDROCHLORIDE tablet, film coated, extended release

Country: Amerika Syarikat

Bahasa: Inggeris

Sumber: NLM (National Library of Medicine)

Bahan aktif:

VERAPAMIL HYDROCHLORIDE (UNII: V3888OEY5R) (VERAPAMIL - UNII:CJ0O37KU29)

Boleh didapati daripada:

A-S Medication Solutions

INN (Nama Antarabangsa):

VERAPAMIL HYDROCHLORIDE

Komposisi:

VERAPAMIL HYDROCHLORIDE 180 mg

Laluan pentadbiran:

ORAL

Jenis preskripsi:

PRESCRIPTION DRUG

Tanda-tanda terapeutik:

Verapamil hydrochloride extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including this drug. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of pharmacolo

Ringkasan produk:

Product: 50090-0584 NDC: 50090-0584-4 30 TABLET, FILM COATED, EXTENDED RELEASE in a BOTTLE NDC: 50090-0584-0 7 TABLET, FILM COATED, EXTENDED RELEASE in a BOTTLE

Status kebenaran:

Abbreviated New Drug Application

Ciri produk

VERAPAMIL HYDROCHLORIDE- VERAPAMIL HYDROCHLORIDE TABLET, FILM COATED,
EXTENDED RELEASE
A-S MEDICATION SOLUTIONS
----------
VERAPAMIL HYDROCHLORIDE EXTENDED-RELEASE TABLETS
RX ONLY
DESCRIPTION
Verapamil Hydrochloride Extended-Release Tablets, USP are calcium ion
influx inhibitor
(slow-channel blocker or calcium ion antagonist). Verapamil
Hydrochloride Extended-
Release Tablets, USP are available for oral administration as brown
colored, oval,
biconvex, film-coated tablets containing 120 mg verapamil
hydrochloride, USP, as brown
colored, oval, biconvex, film-coated tablets containing 180 mg
verapamil hydrochloride,
USP, and as brown colored, oval, biconvex, film-coated tablets
containing 240 mg
verapamil hydrochloride, USP. The tablets are designed for sustained
release of the drug
in the gastrointestinal tract; sustained-release characteristics are
not altered when the
tablet is divided in half.
The structural formula of verapamil HCl, USP is given below:
Benzeneacetonitrile,
α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-
dimethoxy-α-(1-methylethyl) hydrochloride
Verapamil HCl, USP is an almost white, crystalline powder, practically
free of odor, with a
bitter taste. It is soluble in water, freely soluble in chloroform,
sparingly soluble in alcohol
and practically insoluble in ether. Verapamil HCl, USP is not
chemically related to other
cardio active drugs.
In addition to verapamil HCl, USP, the Verapamil Hydrochloride
Extended-Release
Tablets, USP contain the following inactive ingredients: colloidal
silicon dioxide,
hypromellose, magnesium stearate, microcrystalline cellulose,
polyethylene glycol,
povidone, sodium alginate, and titanium dioxide. The following are the
color additives per
tablet strength:
Strength (mg)
Color Additive(s)
120
Ferric Oxide Yellow, Ferric Oxide Red and Ferric Oxide Black
180
Ferric Oxide Yellow, Ferric Oxide Red and Ferric Oxide Black
C
H
N O ·HCl M.W. 491.06 g/mol
27
38
2
4
240
Ferric Oxide Yellow, Ferric Oxide Red and Ferric Oxide Black
Verapamil Hydrochloride Exten