UPHADYL PAED EXPECTORANT

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

DIPHENHYDRAMINE HYDROCHLORIDE; AMMONIUM CHLORIDE

Boleh didapati daripada:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

INN (Nama Antarabangsa):

DIPHENHYDRAMINE HYDROCHLORIDE; AMMONIUM CHLORIDE

Unit dalam pakej:

60 ml; 60 ml

Dikeluarkan oleh:

DUOPHARMA MANUFACTURING (BANGI) SDN BHD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
_ _
UPHADYL PAED EXPECTORANT
Diphenhydramine hydrochloride/Ammonium chloride (7mg/67.5mg per 5ml)
_ _
1
WHAT IS IN THIS LEAFLET
1.
What
Uphadyl
Paed
Expectorant is used for
2.
How
Uphadyl
Paed
Expectorant works
3.
Before
you
use
Uphadyl
Paed Expectorant
4.
How to use Uphadyl Paed
Expectorant
5.
While
you
are
using
Uphadyl Paed Expectorant
6.
Side effects
7.
Storage
and
disposal
of
Uphadyl Paed Expectorant
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT
UPHADYL
PAED
EXPECTORANT IS USED FOR
Uphadyl
Paed
Expectorant
is
used
for
cough
and
allergy
associated
with
respiratory
illness e.g. common cold, flu
and airway inflammation.
HOW
UPHADYL
PAED
EXPECTORANT WORKS
Diphenhydramine
hydrochloride
is
an
antihistamine
that
suppresses
the urge to cough and dries up
secretions
in
the
nose
and
chest. Ammonium chloride is
an
expectorant
that
helps
loosen phlegm.
BEFORE YOU USE UPHADYL PAED
EXPECTORANT
_-_
_ _
_When you must not use it _
Do
not
use
Uphadyl
Paed
Expectorant
if
your
child
is
allergic
to
Diphenhydramine
Hydrochloride
or
Ammonium
Chloride or any of the other
ingredients listed at the end of
the leaflet.
Do
not
use
Uphadyl
Paed
Expectorant
if
your
child
is
taking
monoamine
oxidase
inhibitors (MAOI) (a treatment
for depression).
_-_
_ _
_Before you start to use it _
Before
taking
Uphadyl
Paed
Expectorant you must tell your
doctor
or
pharmacist
if
your
child have, or have had, any of
the medical conditions.
If you are not sure if your child
have, or have had, any of these
conditions,
you
should
raise
those
concerns
with
your
doctor or pharmacist.
_-_
_ _
_Taking other medicines _
Inform
your
doctor
or
pharmacist
before
taking
Uphadyl Paed Expectorant.
Before
using
Uphadyl
Paed
Expectorant
,
it is important to
tell your doctor or pharmacist
if your child is taking any other
medicines,
obtained
with
or
without a doctor’s prescription.
Uphadyl Paed Expectorant
may
enhance
alcohol
and
medicines
used
to
help
your
child
rela

Ciri produk

Glue
Glue
Spine
Glue
Pg 9
Pg 8
Pg 7
Pg 6
Pg 10
Glue
DESCRIPTION
Brown, flavoured and homogenous syrup.
COMPOSITION
Each 5ml contains:
Ammonium Chloride 67.5mg
Diphenhydramine Hydrochloride 7.0 mg
PHARMACODYNAMICS
The combination of Diphenhydramine
Hydrochloride,
an
antihistamine
and
Ammonium Chloride, an expectorant,
will provide rapid relief for cough which
is
associated
with
common
cold
influenza
or
allergic
conditions.
The
menthol will give a soothing effect.
PHARMACOKINETICS
DIPHENHYDRAMINE
HYDROCHLORIDE
Diphenhydramine hydrochloride is well
absorbed
from
the
gastro-intestinal
tract, though high first-pass metabolism
appears to affect systematic availability.
Peak
plasma
concentrations
are
achieved
about
1
to
4
hours
after
administration by mouth. A mean peak
plasma-diphenhydramine concentration
of 110 ng per mL has been reported
after administration of 50 mg four times
daily
by
mouth.
Diphenhydramine
is
widely distributed throughout the body
including
the
CNS.
It
crosses
the
placenta
and
has
been
detected
in
breast milk. Diphenhydramine is highly
bound to plasma proteins. Metabolism is
extensive. Diphenhydramine is excreted
mainly in the urine as metabolites; little
is
excreted
as
unchanged
drug.
Excretion is almost complete within 24
hours of administration.
AMMONIUM CHLORIDE
Ammonium chloride is absorbed from
the
gastro-intestinal
tract.
The
ammonium ion is converted into urea in
the liver; the anion thus liberated into the
blood
stream
and
extracellular
fluid
causes
a
metabolic
acidosis
and
decreases the pH of the urine; this is
followed transient diuresis.
INDICATIONS
For cough and compilation associated
with
allergic
disorders
and
allergic
manifestation of respiratory illness e.g.
common cold, flu, and bronchitis.
CONTRAINDICATIONS
Hypersensitivity
to
any
of
the
ingredients. Patients receiving MAOIs.
SIDE EFFECTS/ADVERSE
The
most
common
side
effect
is
sedation.
Other
side
effects
include
gastric
intestinal
disturbances
such
as
nausea,
vomiting,
diarrhea
or
constipation
and
epigastric
pain.
It
may
produc