Country: Malaysia
Bahasa: Inggeris
Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
Tripolidine Hydrochloride; PSEUDOEPHEDRINE HYDROCHLORIDE
MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.
Tripolidine Hydrochloride; PSEUDOEPHEDRINE HYDROCHLORIDE
1000 Tablets
MALAYSIAN PHARMACEUTICAL INDUSTRIES SDN. BHD.
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _ 1 TRIDIN-P TABLETS Triprolidine Hydrochloride / Pseudoephedrine Hydrochloride (2.5mg/60mg) WHAT IS IN THIS LEAFLET 1. What Tridin-P Tablets is used for 2. How Tridin-P Tablets works 3. Before you use Tridin-P Tablets 4. How to use Tridin-P Tablets 5. While you are using it 6. Side Effects 7. Storage and Disposal of Tridin-P Tablets 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of Revision WHAT TRIDIN-P TABLETS IS USED FOR It is used as a nasopharyngeal (upper part of the throat behind the nose) and otic (linkage between ear and throat) decongestant as well as for the symptomatic treatment of seasonal and perennial (symptoms present throughout the years) allergic rhinitis and non-allergic rhinitis (an inflammation of the membranes inside of the nose). HOW TRIDIN-P TABLETS WORKS Pseudoephedrine Hydrochloride and Triprolidine Hydrochloride are the active ingredients of Tridin-P Tablets. Triprolidine is a long acting antihistamine which works by blocking the effects of the naturally occurring chemical histamine in your body and provides symptomatic relief in allergic conditions triggered by histamine release. Pseudoephedrine shrinks swollen nasal mucous membrane, reduces tissue hyperemia (excess blood in body parts), edema (swelling of soft tissues as a result of excess fluid accumulation) and nasal congestion and clear nasal passages for air exchange. BEFORE YOU USE TRIDIN-P TABLETS - _When you must not use it _ If you are allergic (hypersensitive) to either Triprolidine or Pseudoephedrine and other ingredients of the tablet. If you are allergic to other antihistamines or sympathomimetics. If you are pregnant or breastfeeding. If you are using monoamine oxidase (MAO) inhibitors. The preparation should not be taken during or within 14 days following use of MAO inhibitors. If you are suffering from high blood pressure, overactive thyroid gland, ischemic heart disease (reduced blood supply to the heart) or cerebrova Baca dokumen lengkap
7046-09 TRIDIN-P TABLETS AND SYRUP NAME AND STRENGTH OF ACTIVE INGREDIENT(S) (i) TRIDIN-P TABLET: Each tablet contains: Pseudoephedrine Hydrochloride ……………………… 60mg Triprolidine Hydrochloride …………………………… 2.5mg (ii) TRIDIN-P SYRUP: Each 5ml syrup contains: Pseudoephedrine Hydrochloride ……………………… 30mg Triprolidine Hydrochloride …………………………… 1.25mg PRODUCT DESCRIPTION: (I) TRIDIN-P TABLET: A white, round, scored of diameter 8.5mm flat tablet with ‘MPI’ marking. (II) TRIDIN-P SYRUP: A light yellow liquid with lemon flavour and sweet taste. PHARMACODYNAMICS: Triprolidine is a long acting antihistamine with anticholinergic activity. It is a potent competitive histamine H 1 - receptor antagonist of alkyl (propyl)-amine class which competes with histamine for H 1 - receptor sites on effector cells and provides symptomatic relief in allergic conditions triggered by histamine release. Pseudoephedrine is a stereoisomer of ephedrine which is a sympathomimetic agent with direct and indirect effects on adrenergic receptors. Pseudoephedrine acts on alpha- adrenergic receptors in the mucosa of the respiratory tract, producing vasoconstriction. It shrinks swollen nasal mucuos membranes, reduces tissue hyperemia, edema and nasal congestion, and increases nasal airway patency. PHARMACOKINETICS: Triprolidine is readily absorbed from the gastrointestinal tract after oral administration. It is mostly metabolised in the liver and excreted usually mainly as metabolites in the urine. It has a rapid onset and long duration of action. The maximum effect occurs in about 3 1 / 2 hours; the duration of effect is about 12 hours. Pseudoephedrine is readily and completely absorbed from the gastrointestinal tract. It is resistant to metabolism by monoamine oxidase and is largely excreted unchanged in the urine. It has a half-life of several hours; elimination is enhanced and half-life accordingly shorter in acidic urine. INDICATION: TRIDIN-P which is the combinatio Baca dokumen lengkap