TORQUITE TABLETS 25 MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

QUETIAPINE FUMARATE

Boleh didapati daripada:

LABORATORIES TORRENT (MALAYSIA) SDN. BHD.

INN (Nama Antarabangsa):

QUETIAPINE FUMARATE

Unit dalam pakej:

10tablet Tablets; 30tablet Tablets; 100tablet Tablets

Dikeluarkan oleh:

TORRENT PHARMACEUTICALS LTD.

Risalah maklumat

TORQUITE TABLETS
_ _
Quetiapine Fumarate (25 mg, 300 mg)
_ _
_ _
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What is Torquite used for
2.
How Torquite works
3.
Before you use Torquite
4.
How to use Torquite
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Torquite
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
11.
Serial Number
WHAT TORQUITE IS USED FOR
Torquite can be used to treat several
illnesses, such as:
•
Bipolar depression: where you feel
sad. You may find that you feel
depressed, feel guilty, lack energy,
lose your appetite or can’t sleep.
•
Mania: where you may feel very
excited,
elated,
agitated,
enthusiastic or hyperactive or have
poor
judgment
including
being
aggressive or disruptive.
•
Schizophrenia:
where
you
may
hear or feel things that do not there,
believe in things that are not true or
feel unusually suspicious, anxious,
confused,
guilty,
tense
or
depressed.
Your doctor may continue to prescribe
Torquite
even
when
you
are
feeling
better.
HOW TORQUITE WORKS
Torquite
contains
a
medicine
called
quetiapine. This belongs to a group of
medicines
called
antipsychotics.
Torquite
helps
to
correct
chemical
imbalances in the brain.
BEFORE YOU USE TORQUITE
-
_When you must not use it _
•
If you are allergic (hypersensitive)
to quetiapine or any of the other
ingredients
of
Torquite
(see
Section 8: Further information).
•
If
you
are
taking
any
of
the
following medicines:
-
Some medicines for HIV.
-
Azole
medicines
(for
fungal
infections).
-
Erythromycin
or
clarithromycin (for infections).
-
Nefazodone (for depression).
Do
not
take
Torquite
if
the
above
applies to you. If you are not sure, talk
to
your
doctor
or
pharmacist
before
taking Torquite.
_Pregnancy and lactation _
_ _
_ _
Do
not
take
Torquite
if
you
are
pregnant, trying to get pregnant or think
you
may
be
pregnant.
If
you
get
pregnant
while
taking
Torquite,
stop
taking it immediately and contact your
doctor.
Do not take Torquite until you

Ciri produk

xxxxxxxx-5253
For the use of a Registered Medical Practitioner or a Hospital or a
Laboratory only.
BRAND OR PRODUCT NAME
TORQUITE TABLETS 25 MG
TORQUITE TABLETS 300 MG
NAME AND STRENGTH OF ACTIVE INGREDIENT
TORQUITE TABLETS 25 MG
Each film coated tablet contains:
Quetiapine Fumarate Ph.Eur.
equivalent to Quetiapine 25 mg
Colours: Yellow oxide of Iron, Red Oxide of Iron and Titanium Dioxide
TORQUITE TABLETS 300 MG
Each film coated tablet contains:
Quetiapine Fumarate Ph.Eur.
equivalent to Quetiapine 300 mg
Colour: Titanium Dioxide
PRODUCT DESCRIPTION
TORQUITE TABLETS 25 MG
Brownish red coloured, round, biconvex, film coated tablets plain on
both sides.
TORQUITE TABLETS 300 MG
White to off white, capsule shaped, biconvex, film coated tablets with
break line on
both sides.
DOSAGE FORM
Film coated tablet
PHARMACODYNAMIC PROPERTIES
Pharmacotherapeutic group: Antipsychotics
MECHANISM OF ACTION
Quetiapine is an atypical antipsychotic agent. Quetiapine and the
active human
plasma metabolite, norquetiapine interact with a broad range of
neurotransmitter
receptors. Quetiapine and norquetiapine exhibit affinity for brain
serotonin (5HT2,)
and dopamine D1, and D2- receptors. It is this combination of receptor
antagonism
with a higher selectivity for 5HT2, relative to D2- receptors, which
is believed to
contribute to the clinical antipsychotic properties and low
extrapyramidal side effect
(EPS). Quetiapine has no affinity for the norepinephrine transporter
(NET) and low
affinity for the serotonin 5HT1A receptor, whereas norquetiapine has
high affinity for
both. Inhibition of NET and partial agonist action at 5HT1A sites by
norquetiapine
may contribute to quetiapine’s therapeutic efficacy as an
antidepressant. Quetiapine
and norquetiapine have high affinity at histaminergic and adrenergic
alpha 1
receptors and moderate affinity at adrenergic alpha2 receptors.
Quetiapine also has
low or no affinity for muscarinic receptors, while norquetiapine has
moderate to high
affinity for several muscarinic receptor subtypes.
PHARMACODYN