TERNOLOL 50 FILM-COATED TABLET

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ATENOLOL

Boleh didapati daripada:

HOVID BERHAD

INN (Nama Antarabangsa):

ATENOLOL

Unit dalam pakej:

100Tablet Tablets; 500 Tablets; 1000 Tablets; 30 Tablets

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
TERNOLOL FILM-COATED TABLET
Atenolol (50 mg, 100 mg)
1
1.
What Ternolol is used for
2.
How Ternolol works
3.
Before you use Ternolol
4.
How to use Ternolol
5.
While you are using Ternolol
6.
Side effects
7.
Storage and Disposal of Ternolol
8.
Product description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
11.
Serial Number
WHAT TERNOLOL IS USED FOR
This medicine contains the active
ingredient Atenolol.
Used to treat:
•
hypertension (high blood
pressure)
•
angina pectoris (chest pain or
discomfort)
•
acute myocardial infarction (heart
attack)
•
cardiac arrhythmias (irregular
heart rhythm)
HOW TERNOLOL WORKS
Atenolol belongs to a family of
medicines called beta blockers.
It works by slowing down or
decreasing the heart’s need for blood
and oxygen. This results in reduced
workload for the heart.
BEFORE YOU USE TERNOLOL
_- When you must not use it _
Do not take this medicine if:
•
you are allergic to atenolol or any
of the excipients
•
you have cardiogenic shock
(failure of pump action of the
heart)
•
you have heartblock
•
you have overt cardiac failure
(heart failure)
•
you have sinus bradycardia (a
regular but usually slow
heartbeat) or reversible
obstructive airways disease.
_- Before you start to use it _
Tell your doctor if:
•
you have congestive heart failure
•
you have poor cardiac reserve (the
ability of your heart to work in
strenuous conditions)
•
you have impaired kidney/liver
function.
_- Taking other medicines _
Talk to your doctor or pharmacist if
you are taking any other medicines in
any form including any that you buy
or obtained without a prescription.
Some medicines interfere with
Ternolol. Tell your doctor if you are
taking:
•
Clonidine (used to treat ADHD
(Attention Deficit Hyperactivity
Disorder)
•
Reserpine (used for the control of
high blood pressure)
•
Phenylephrine (used as
decongestant)
Other interactions not stated may
occur. Talk to your doctor or
pharmacist if you have any other
con

Ciri produk

TERNOLOL TABLET
FRONT
VITERxx-0 (BRU)
DESCRIPTION
Ternolol 50 mg
8mm, round, orange film-coated tablet with shallow convex
faces, bevel-edged and heart-shaped protrusion.
Ternolol 100 mg
10mm, round, orange film-coated tablet with shallow convex
faces bevel-edged and heart-shaped protrusion.
COMPOSITION
Ternolol 50 mg
Atenolol 50 mg per tablet.
Ternolol 100 mg
Atenolol 100 mg per tablet.
PHARMACODYNAMICS
Atenolol is a beta-blocker which is beta1-selective (i.e. acts
preferentially on beta1-adrenergic receptors in the heart).
Selectivity decreases with increasing dose. Atenolol is without
intrinsic sympathomimetic and membrane stabilising activities
and as with other beta-blockers, has negative inotropic effects
(and is therefore contraindicated in uncontrolled heart failure).
As with other beta-blockers, the mode of action of atenolol in
the treatment of hypertension is unclear. It is probably the
action of atenolol in reducing cardiac rate and contractility
which
makes
it
effective
in
eliminating
or
reducing
the
symptoms of patients with angina.
It is unlikely that any
additional ancillary properties possessed by S (-) atenolol, in
comparison with the racemic mixture, will give rise to different
therapeutic effects.
Ternolol is effective for at least 24 hours after a single oral
dose. The drug facilitates compliance by its acceptability to
patients and simplicity of dosing. The narrow dose range and
early patient response ensure that the effect of the drug in
individual
patients
is
quickly
demonstrated.
Tenormin
is
compatible
with
diuretics,
other
hypotensive
agents
and
antianginal
agents
(see
Interactions).
Since
it
acts
preferentially on beta-receptors in the heart, Tenormin may,
with care, be used successfully in the treatment of patients
with respiratory disease, who cannot tolerate non-selective
beta-blockers.
PHARMACOKINETICS
Following
intravenous
administration,
the
blood
levels
of
atenolol decay tri-exponentially with an elimination half-life of
about 6 hours. Throughout the intravenous dose range of 5-1