TELDAY TABLETS 40 MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

TELMISARTAN

Boleh didapati daripada:

LABORATORIES TORRENT (MALAYSIA) SDN. BHD.

INN (Nama Antarabangsa):

TELMISARTAN

Unit dalam pakej:

4 x 7'stablet Tablets

Dikeluarkan oleh:

TORRENT PHARMACEUTICAL LIMITED

Risalah maklumat

TELDAY TABLETS
Telmisartan (40mg , 80mg)
_ _
_ _
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What is TELDAY used for
2.
How TELDAY works
3.
Before you use TELDAY
4.
How to use TELDAY
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of TELDAY
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT TELDAY IS USED FOR
TELDAY
contains
Telmisartan.
It
is
used
to
treat
essential
hypertension
(high
blood
pressure).
‘Essential’
means that the high blood pressure is
not caused by any other condition.
Also
used
to
reduce
cardiovascular
events (i.e. heart attack or stroke) in
adults who are at risk because they have
a reduced or blocked blood supply to
the heart or legs, or have had a stroke or
have
high risk diabetes. Your
doctor
can tell you if you are at high risk for
such events.
HOW TELDAY WORKS
Telmisartan
belongs
to
a
class
of
medicines
known
as
angiotensin
II
receptor antagonists. Angiotensin II is a
substance
produced
in
your
body,
which
causes
your
blood
vessels
to
narrow,
thus
increasing
your
blood
pressure. Telmisartan blocks the effect
of
angiotensin
II
so
that
the
blood
vessels relax, and your blood pressure
is lowered.
BEFORE YOU USE TELDAY
-
_When you must not use it _
If you are allergic (hypersensitive) to
Telmisartan
or
any
other
ingredients
included in TELDAY tablets.
If
you
are
more
than
3
months
pregnant.
If you have severe liver problems such
as
cholestasis
or
biliary
obstruction
(problems
with
drainage
of
the
bile
from the liver and gall bladder) or any
other severe liver disease.
_Pregnancy and lactation_
_ _
Do
not
take
TELDAY
if
you
are
pregnant, trying to get pregnant or think
you may be pregnant. TELDAY is not
recommended in early pregnancy, and
must not be taken if you are more than
3
months
pregnant,
as
it
may
cause
serious harm to your baby if used at
that stage.
Do not take TELDAY if you are breast-
feeding. TELDAY is not recommended
for mothers who are breast-feeding, and
your
doctor
may
choose

Ciri produk

Proposed Prescribing Information
For the use of a Registered Medical Practitioner or a Hospital or a
Laboratory
TELDAY TABLETS 40/80 MG
TELMISARTAN TABLETS 40/80 MG
BRAND OR PRODUCT NAME
TELDAY TABLETS 40/80 MG
NAME AND STRENGTH OF ACTIVE SUBSTANCE(S)
TELDAY TABLETS 40 MG
Each uncoated tablet contains: Telmisartan Ph. Eur……… 40 mg
TELDAY TABLETS 80 MG
Each uncoated tablet contains: Telmisartan Ph. Eur……… 80 mg
PRODUCT DESCRIPTION
TELDAY TABLETS 40 MG
White or off-white to yellowish oblong biconvex uncoated tablets with
break line on one side and
plain on the other side.
TELDAY TABLETS 80 MG
White or off-white to yellowish oval biconvex uncoated tablets with
break line on one side and plain
on other side.
DOSAGE FORM
Uncoated tablet
PHARMACODYNAMICS / PHARMACOKINETICS
PHARMACODYNAMICS
Pharmacotherapeutic group: Angiotensin II Antagonists, plain, ATC
Code: C09CA07.
Mechanism of action
Telmisartan is an orally active and specific angiotensin II receptor
(type AT1) antagonist. Telmisartan
displaces angiotensin II with very high affinity from its binding site
at the AT1 receptor subtype, which
is responsible for the known actions of angiotensin II. Telmisartan
does not exhibit any partial agonist
activity at the AT1 receptor. Telmisartan selectively binds the AT1
receptor. The binding is long-
lasting.
Telmisartan
does
not
show
affinity
for
other
receptors,
including
AT2
and other less
characterized AT receptors. The functional role of these receptors is
not known, nor is the effect of their
possible
overstimulation
by
angiotensin
II,
whose
levels
are
increased
by
telmisartan. Plasma
aldosterone levels are decreased by telmisartan. Telmisartan does not
inhibit human plasma renin or
block ion channels. Telmisartan does not inhibit angiotensin
converting enzyme (kininase II), the
enzyme which also degrades bradykinin. Therefore, it is not expected
to potentiate bradykinin-
mediated adverse effects.
In human, an 80 mg dose of telmisartan almost completely inhibits the
angiotensin II evoked blood
pressure incr