SOLBID TABLET 10MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ISOSORBIDE DINITRATE

Boleh didapati daripada:

SM PHARMACEUTICALS SDN. BHD.

INN (Nama Antarabangsa):

ISOSORBIDE DINITRATE

Unit dalam pakej:

1000Tablet Tablets; 10Tablet Tablets; 1000Tablet Tablets; 100Tablet Tablets; 2500 Tablet Tablets; 100 Tablet Tablets; 5000 Tablet Tablets

Dikeluarkan oleh:

SM PHARMACEUTICALS SDN. BHD.

Risalah maklumat

_Consumer Medication Information Leaflet (RiMUP) _
SOLBID TABLET
Isosorbide Dinitrate (10mg)
__________________________________________________________________________________________________________________________
_______________________________________________________________________________________________________________
1
WHAT IN THIS LEAFLET
1. WHAT SOLBID TABLET IS USED FOR
2.HOW SOLBID TABLET WORKS
3.BEFORE YOU USE SOLBID TABLET
4.HOW TO USE SOLBID TABLET
5.WHILE YOU ARE USING SOLBID TABLET
6.SIDE EFFECTS
7. STORAGE AND DISPOSAL OF SOLBID TABLET
8.PRODUCT DESCRIPTION
9.MANUFACTURER AND PRODUCT REGISTRATION HOLDER
10.DATE OF REVISION WHAT SOLBID TABLET IS USED FOR
Isosorbide dinitrate is used as a preventive
measure in the treatment of angina pectoris.
(described as pressure, squeezing, burning,
or tightness in the chest).
HOW SOLBID TABLET WORKS
Solbid Tablet is an anti-anginal agent which
relaxes the blood vessels in the body,
allowing them to widen. This lets more
blood flow through the blood vessels,
which reduces the work the heart has to do
to pump blood. This reduces the oxygen
needs of the heart and decreases chest pain.
BEFORE YOU USE SOLBID TABLET
_WHEN YOU MUST NOT TAKE IT _
If you are hypersensitive to isosorbide
dinitrate or other nitrates or nitrites.
_BEFORE YOU START TO TAKE IT _
Tell your doctor if you have allergies to any
other medicines, foods, preservatives or
dyes.
Tell your doctor if you have any of
following medical conditions:
•
Severe hypotension(low blood
pressure).
•
Hypovolaemia (a state of decreased
blood volume).
•
Anaemia (a decrease in the amount of
red blood cells).
•
Constrictive pericarditis (inflammation
of the pericardium - sac-like
membrane that surrounds the heart).
•
Raised intracranial pressure (pressure
inside the skull).
•
Closed-angle glaucoma
(buildup of pressure inside the eye).
It should be used with caution if you have:
•
Severely impaired kidney or liver
function.
•
Hypothyroidism (reduced level of
thyroid hormone).
•
Malnutrition
(lack o

Ciri produk

additional
measures
unnecessary.
However,
if
additional
correction of severe hypotension is
required, administration of an intravenous alpha -
adrenergic
agonist
such
as
methoxamine
or
phenylephrine
may be considered; epinephrine
should be avoided since it aggravates the shock - like
reaction.
The
administration
of
oxygen,
with
assisted
respiration
may
be
necessary
in
the
severe
poisoning; if methaemoglobinaemia occurs give
methylene blue 1 mg per kg of body weight by slow
intravenous
injection.
The
circulation
may
be
maintained with infusions of plasma or suitable
electrolyte solutions. In the case of severe poisoning
with tablets the stomach should be emptied by
lavage
STORAGE CONDITIONS, USER INSTRUCTIONS
AND PHARMACEUTICAL PRECAUTIONS:
Store below 25°C, in a well closed container.
USER INSTRUCTIONS:
Avoid alcoholic beverages.
PHARMACEUTICAL PRECAUTIONS:
Loss of potency is accelerated by exposure to heat
and moisture
PACKING / PACK SIZES:
Plastic container of 100 tablets and 1000 tablets.
Blister pack of 10 tablets, 100 x 100’s / box and 500
x 10’s/box.
SHELF LIFE: 3 Years
NAME AND ADDRESS OF MANUFACTURER:
SM PHARMACEUTICALS SDN BHD (218620-M)
Lot 88, Sungai Petani Industrial Estate
08000 Sungai Petani,
Kedah Darul Aman,
Malaysia.
SM PHARMACEUTICALS SDN. BHD.
SOLBID TABLET 10 MG
_(ISOSORBIDE DINITRATE 10 MG)_
DESCRIPTION:
Yellowish Orange, clean, dry, uniform capsule shaped
with flat surface and breakline, uncoated tablet.
ACTIONS AND MODE OR MECHANISMS OF
ACTION:
Anti-anginal or cardiac load – reducing agent – Not
specifically known but thought to cause a reduction
of myocardial oxygen demand. This is attributed to a
reduction in left ventricular pre-load and after-load
because of venous (predominantly) and arterial
dilation with a more efficient redistribution of blood
flow within the myocardium
PHARMACOLOGY:
Protein Binding: Moderate
Metabolism:
Hepatic
(very
rapid
and
nearly
complete) and in blood (enzymatically). Oral dosage
form undergoes extensive first – pass metabolism.
Onset of action:
Not