Amerika Syarikat - Inggeris - NLM (National Library of Medicine)

specgx llc - clomipramine hydrochloride (unii: 2lxw0l6gwj) (clomipramine - unii:nuv44l116d) - clomipramine hydrochloride 25 mg - anafranil™ (clomipramine hydrochloride) capsules usp is indicated for the treatment of obsessions and compulsions in patients with obsessive-compulsive disorder (ocd). the obsessions or compulsions must cause marked distress, be time-consuming, or significantly interfere with social or occupational functioning, in order to meet the dsm-iii-r (circa 1989) diagnosis of ocd. obsessions are recurrent, persistent ideas, thoughts, images, or impulses that are ego-dystonic. compulsions are repetitive, purposeful, and intentional behaviors performed in response to an obsession or in a stereotyped fashion, and are recognized by the person as excessive or unreasonable. the effectiveness of anafranil for the treatment of ocd was demonstrated in multicenter, placebo-controlled, parallel-group studies, including two 10-week studies in adults and one 8-week study in children and adolescents 10 to 17 years of age. patients in all studies had moderate-to-severe ocd (dsm-iii), with mean baseline ratings on the yale-brown obsessive compulsive scale (ybocs) ranging from 26 to 28 and a mean baseline rating of 10 on the nimh clinical global obsessive compulsive scale (nimh-oc). patients taking cmi experienced a mean reduction of approximately 10 on the ybocs, representing an average improvement on this scale of 35% to 42% among adults and 37% among children and adolescents. cmi-treated patients experienced a 3.5 unit decrement on the nimh-oc. patients on placebo showed no important clinical response on either scale. the maximum dose was 250 mg/day for most adults and 3 mg/kg/day (up to 200 mg) for all children and adolescents. the effectiveness of anafranil for long-term use (i.e., for more than 10 weeks) has not been systematically evaluated in placebo-controlled trials. the physician who elects to use anafranil for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient (see dosage and administration ). anafranil is contraindicated in patients with a history of hypersensitivity to anafranil or other tricyclic antidepressants. monoamine oxidase inhibitors (maois) the use of maois intended to treat psychiatric disorders with anafranil or within 14 days of stopping treatment with anafranil is contraindicated because of an increased risk of serotonin syndrome.  the use of anafranil within 14 days of stopping an maoi intended to treat psychiatric disorders is also contraindicated (see  warnings   and dosage and administration ). starting anafranil in a patient who is being treated with linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome (see  warnings   and dosage and administration ). myocardial infarction anafranil is contraindicated during the acute recovery period after a myocardial infarction. anafranil has not been systematically studied in animals or humans for its potential for abuse, tolerance, or physical dependence. while a variety of withdrawal symptoms have been described in association with anafranil discontinuation (see precautions, withdrawal symptoms ), there is no evidence for drug-seeking behavior, except for a single report of potential anafranil abuse by a patient with a history of dependence on codeine, benzodiazepines, and multiple psychoactive drugs. the patient received anafranil for depression and panic attacks and appeared to become dependent after hospital discharge. despite the lack of evidence suggesting an abuse liability for anafranil in foreign marketing, it is not possible to predict the extent to which anafranil might be misused or abused once marketed in the u.s. consequently, physicians should carefully evaluate patients for a history of drug abuse and follow such patients closely.

Amerika Syarikat - Inggeris - NLM (National Library of Medicine)

mizner bioscience, llc - clomipramine hydrochloride (unii: 2lxw0l6gwj) (clomipramine - unii:nuv44l116d) - clomipramine hydrochloride tablets are to be used as part of a comprehensive behavioral management program to treat separation anxiety in dogs greater than 6 months of age. inappropriate barking or destructive behavior, as well as inappropriate elimination (urination or defecation) may be alleviated by the use of clomipramine hydrochloride tablets in conjunction with behavior modification. separation anxiety is a complex behavior disorder displayed when the owner (or other attachment figure) leaves the dog. the signs of separation anxiety evaluated in controlled trials were vocalization, destructive behavior, excessive salivation, and inappropriate elimination. in the absence of the owner or attachment figure, dogs with separation anxiety may exhibit one or more of these clinical signs. although the owner (attachment figure) may inadvertently misinterpret this behavior, which only happens in their absence, as spiteful, it is thought to be the result of anxiety experienced by the dog. punishment is not conside

Amerika Syarikat - Inggeris - NLM (National Library of Medicine)

zydus lifesciences limited - clomipramine hydrochloride (unii: 2lxw0l6gwj) (clomipramine - unii:nuv44l116d) - clomipramine hydrochloride capsules, usp are indicated for the treatment of obsessions and compulsions in patients with obsessive-compulsive disorder (ocd). the obsessions or compulsions must cause marked distress, be time-consuming, or significantly  interfere with  social  or  occupational  functioning,  in  order  to  meet  the dsm-iii-r (circa 1,989) diagnosis of ocd. obsessions are recurrent, persistent ideas, thoughts, images, or impulses that are ego  dystonic. compulsions are repetitive, purposeful, and intentional behaviors performed in response to an obsession or in a stereotyped fashion, and are recognized by the person as excessive or unreasonable. the effectiveness of clomipramine hydrochloride for the treatment of ocd was demonstrated in multicenter, placebo-controlled, parallel-group studies, including two 10-week studies in adults and one 8-week study in children and adolescents 10 to 17 years of age. patients in all studies had moderate-to-severe ocd (dsm-iii), with mean baseline ratings on t

Malta - Inggeris - Medicines Authority

remedica limited limassol industrial estate, aharnon street, 3056 limassol, cyprus - clomipramine hydrochloride - film-coated tablet - clomipramine hydrochloride 10 mg - psychoanaleptics

Malta - Inggeris - Medicines Authority

remedica limited limassol industrial estate, aharnon street, 3056 limassol, cyprus - clomipramine hydrochloride - film-coated tablet - clomipramine hydrochloride 25 mg - psychoanaleptics

Amerika Syarikat - Inggeris - NLM (National Library of Medicine)

attix pharmaceuticals inc - clomipramine hydrochloride (unii: 2lxw0l6gwj) (clomipramine - unii:nuv44l116d) -

Amerika Syarikat - Inggeris - NLM (National Library of Medicine)

h3 medical inc. - clomipramine hydrochloride (unii: 2lxw0l6gwj) (clomipramine - unii:nuv44l116d) -

Kanada - Inggeris - Health Canada

genpharm ulc - clomipramine hydrochloride - tablet - 25mg - clomipramine hydrochloride 25mg - tricyclics and other norepinephrine-reuptake inhibitors

Kanada - Inggeris - Health Canada

genpharm ulc - clomipramine hydrochloride - tablet - 50mg - clomipramine hydrochloride 50mg - tricyclics and other norepinephrine-reuptake inhibitors

Kanada - Inggeris - Health Canada

genpharm ulc - clomipramine hydrochloride - tablet - 10mg - clomipramine hydrochloride 10mg - tricyclics and other norepinephrine-reuptake inhibitors