REXOM VITAMIN B-6 TABLET 20MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PYRIDOXINE HCL/VITAMIN B6

Boleh didapati daripada:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN (Nama Antarabangsa):

PYRIDOXINE HCL/VITAMIN B6

Unit dalam pakej:

100 Tablets; 100 Tablets; 1000 Tablets; 100 Tablets; 1000 Tablets

Dikeluarkan oleh:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
REXOM TM VITAMIN B-6 TABLET 20MG
Pyridoxine Hydrochloride (Vitamin B6) (20mg)
1
WHAT IS IN THIS LEAFLET
1.
What
REXOM
TM
Vitamin
B-6
is
used for
2.
How REXOM
TM
Vitamin B-6 works
3.
Before you use REXOM
TM
Vitamin
B-6
4.
How to use REXOM
TM
Vitamin B-6
5.
While
you
are
using
REXOM
TM
Vitamin B-6
6.
Side effects
7.
Storage and disposal of REXOM
TM
Vitamin B-6
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT REXOM
TM VITAMIN B-6 IS USED
FOR
For the treatment of isoniazid-induced
peripheral
neuritis
and
pyridoxine
deficiency state (For adults and children
over 12 years).
HOW REXOM
TM VITAMIN B-6 WORKS
REXOM
TM
Vitamin
B-6
contains
pyridoxine
hydrochloride
which
is
vitamin B6. It helps the body convert
food
into
fuel,
metabolize
fats
and
proteins, maintain proper functioning of
nerves and produce red blood cells.
BEFORE YOU USE REXOM
TM VITAMIN
B-6
_-When you must not use it _
Do not take this medicine if you have:
•
An allergy to any of the ingredients
listed in this leaflet.
_-Before you start to use it_
_Pregnancy and lactation_
Talk to you doctor before taking this
medicine
if
you
are
pregnant,
might
become pregnant or are breastfeeding.
Pyridoxine is not recommended during
the first trimester of pregnancy.
_-Taking other medicines _
Inform your doctor or pharmacist before
taking this medicines, including any that
you get without a prescription from your
pharmacy, supermarket or health food
shop.
Some
medicines
and
REXOM
TM
Vitamin B-6 may interfere with each
other.
They
may
be
affected
by
REXOM
TM
Vitamin B-6 or may affect
how well it works.
HOW TO USE REXOM
TM VITAMIN B-6
_-How much to use _
Always
use
REXOM
TM
Vitamin
B-6
exactly as your doctor has prescribed.
You should check with your doctor or
pharmacist if in doubt.
The usual dose:
_Adults and children over 12 years old _
Isoniazid neuropathy:-
Prophylaxis 10mg daily
Treatment
50mg
three
times
daily
(Adults)
Treatment 30-50mg two to three times a
day (child

Ciri produk

REXOM
TM
VITAMIN B-6 TABLET 20MG
NAME AND STRENGTH OF ACTIVE INGREDIENTS:
Each tablet contains:
Pyridoxine HCl (B
6
)
……………………………………………………………20mg
PRODUCT DESCRIPTION
Yellow colour, round with top scored tablet.
PHARMACODYNAMICS
_Vitamin B6 (Pyridoxine) _
Pyridoxine, once absorbed, is rapidly converted to the co-enzymes
pyridoxal phosphate and
pyridoxamine phosphate which play an essential role in protein
metabolism. Convulsions and
hypochromic anaemia have occurred in infants deficient in pyridoxine.
PHARMACOKINETICS
_Vitamin B6 (Pyridoxine) _
Pyridoxine is absorbed from the gastro-intestinal tract and converted
to the active pyridoxal
phosphate which is bound to plasma proteins. It is excreted in the
urine as 4-pyridoxic acid.
INDICATIONS
Pyridoxine is indicated for adults and children over 12 years old in
the treatment of isoniazid-
induced peripheral neuritis and pyridoxine deficiency states.
RECOMMENDED DOSE
_Adults and children over 12 years old _
Isoniazid neuropathy:-
Prophylaxis 10mg daily
Treatment 50mg three times daily (Adults)
Treatment 30-50mg two to three times a day (children over 12 years)
Deficiency states:-
20-50mg up to three times daily
_Elderly _
As for adults.
_Paediatric population _
Little information is available on the use of pyridoxine in children
under 12 years. Doses of
4mg/Kg have been used to treat children with familial pyridoxine
resistance.
ROUTE OF ADMINISTRATION
Oral
CONTRAINDICATIONS
Hypersensitivity to the pyridoxine or to any of the excipients.
WARNING AND PRECAUTIONS
If symptoms persist or worsen, seek medical advice. Do not exceed the
stated dose.
INTERACTIONS WITH OTHER MEDICAMENTS
Pyridoxine antagonises the therapeutic effect of levodopa when it is
used without a dopa-
decarboxylase inhibitor. Larger doses of pyridoxine can cause a
reduction in serum phenytoin
and phenobarbitone levels in some patients. Pyridoxine requirements
have been reported to be
increased by oral contraceptives, hydralazine, isoniazid, cycloserine
and p