REXOM ASCORBIC ACID TABLET 100MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ASCORBIC ACID

Boleh didapati daripada:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

INN (Nama Antarabangsa):

ASCORBIC ACID

Unit dalam pakej:

100 Tablets

Dikeluarkan oleh:

KCK PHARMACEUTICAL INDUSTRIES SDN. BHD.

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
REXOM ASCORBIC ACID TABLET
Ascorbic Acid (100 mg)
1
WHAT IS IN THIS LEAFLET
1.
What Rexom Ascorbic Acid is used
for
2.
How Rexom Ascorbic Acid works
3.
Before
you
use
Rexom
Ascorbic
Acid
4.
How to use Rexom Ascorbic Acid
5.
While
you
are
using
Rexom
Ascorbic Acid
6.
Side effects
7.
Storage
and
disposal
of
Rexom
Ascorbic Acid
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT REXOM ASCORBIC ACID IS USED FOR
For Vitamin C deficiency.
HOW REXOM ASCORBIC ACID WORKS
Rexom Ascorbic acid contains ascorbic
acid which will prevent ascorbic acid
deficiency in the body.
BEFORE YOU USE REXOM ASCORBIC ACID
_-When you must not use it _
Do not take this medicine if you have:
•
An allergy to any of the ingredients
listed in this leaflet.
•
Hyperoxaluria
(too
much
oxalate
crystals in the urine).
_ _
_-Before you start to use it_
Talk to you doctor before taking this
medicine.
_Pregnancy and lactation_
Talk to you doctor before taking this
medicine
if
you
are
pregnant,
might
become pregnant or are breastfeeding.
Pregnant
women
should
exercise
caution.
Ascorbic
acid
is
excreted
in
breast milk.
_-Taking other medicines _
Inform your doctor or pharmacist before
taking this medicines, including any that
you get without a prescription from your
pharmacy, supermarket or health food
shop.
Some medicines and Rexom Ascorbic
Acid may interfere with each other. They
may
be
affected
by
Rexom
Ascorbic
Acid or may affect how well it works.
•
Ascorbic
acid
increases
the
renal
excretion of amphetamine.
•
The plasma concentration of ascorbate
is
decreased
by
smoking
and
oral
contraceptives.
•
Ascorbic acid increases the absorption
of iron.
•
Concomitant administration of aspirin
and ascorbic acid may interfere with
absorption of ascorbic acid.
•
Renal
excretion
of
salicylate
is
not
affected and does not lead to reduce
anti-inflammatory effects of aspirin.
•
Concomitant
administration
of
aluminium-
containing
antacids
may
increase
urinar

Ciri produk

REXOM ASCORBIC ACID TABLET 100MG
NAME AND STRENGTH OF ACTIVE INGREDIENTS:
Ascorbic Acid
……………………………………………………………….100mg
PRODUCT DESCRIPTION
Orange, Round and top scored tablet.
PHARMACODYNAMICS
_Vitamin C (Ascorbic Acid) _
Ascorbic acid, coupled with dehydroascorbic acid to which it is
reversibly oxidised, has a
variety of functions in cellular oxidation processes. Ascorbic acid is
required in several
important hydroxylation, including the conversion of proline to
hydroxyproline (and thus in
collagen formation e.g. for intercellular substances and during wound
healing); the formation
of
the
neurotransmitters
5-hydroxytryptamine
from
tryptophan
and
noradrenaline
from
dopamine, and the biosynthesis of carnitine from lysine and
methionine. Ascorbic acid appears
to have an important role in metal ion metabolism, including the
gastrointestinal absorption of
iron and its transport between plasma and storage organs. There is
evidence that ascorbic acid
is required for normal leucocyte functions and that it participates in
the detoxification of
numerous foreign substances by the hepatic microsomal system.
Deficiency of ascorbic acid
leads to scurvy, which may be manifested by weakness, fatigue,
dyspnoea, aching bones,
perifollicular hyperkeratosis, petechia and ecchymosis, swelling and
bleeding of the gums,
hypochromic anaemia and other haematopoietic disorders, together with
reduced resistance to
infections and impaired wound healing.
PHARMACOKINETICS
_Absorption _
Ascorbic acid is well absorbed from the gastrointestinal tract.
_Distribution _
Ascorbic acid is widely distributed to all tissues. Body stores of
ascorbic acid normally are
about 1.5g. The concentration is higher in leucocytes and platelets
than in erythrocytes and
plasma.
_Elimination _
Ascorbic acid additional to the body's needs, generally amounts above
200mg daily, is rapidly
eliminated; unmetabolized ascorbic acid and its inactive metabolic
products are chiefly
excreted in the urine. The amount of ascorbic