RENITEC 20MG TABLET

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ENALAPRIL MALEATE

Boleh didapati daripada:

ORGANON MALAYSIA SDN. BHD.

INN (Nama Antarabangsa):

ENALAPRIL MALEATE

Unit dalam pakej:

30Tablet Tablets

Dikeluarkan oleh:

Organon Pharma (UK) Limited

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
RENITEC
®
Enalapril Maleate (5mg, 10mg, 20mg)
Copyright 2021 Organon group of companies. All rights reserved.
WHAT IS IN THIS LEAFLET
1.
What
_RENITEC _
is used for
2.
How
_RENITEC _
works
3.
Before you take
_RENITEC_
4.
How to take
_RENITEC_
_5._
_ _
While you are taking
_ _
_RENITEC _
6.
Side effects
7.
Storage and disposal of
_RENITEC _
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of revision
WHAT _RENITEC _IS USED FOR
_RENITEC _
is a tablet.
_RENITEC _
is a medication that
belongs to the group of medicine
called angiotensin converting
enzyme inhibitors, (ACE
inhibitors).
Your doctor has prescribed
_RENITEC _
to treat your
hypertension (high blood pressure)
or heart failure (weakening of heart
function).
_RENITEC _
is also used
for the prevention of symptomatic
heart failure.
In many patients with heart failure
who have symptoms,
_RENITEC _
slows the worsening of heart
failure, reduces the need to go to
the hospital as a result of heart
failure, and helps some of these
patients to live longer.
In many patients with early stage
heart failure prior to the
development of symptoms,
_RENITEC _
helps to prevent the
weakening of heart function and to
slow the development of symptoms
(for instance, shortness of breath,
tiredness after light physical
activity such as walking, or
swelling of the ankles and feet).
These patients may be less likely to
have hospital stays as a result of
heart failure.
By taking
_RENITEC_
, some heart
failure patients may lessen their
risk of heart attack.
HOW _RENITEC _WORKS
_RENITEC _
works by widening your
blood vessels to make it easier for
the heart to pump blood to all parts
of your body. This helps to reduce
high blood pressure. In many
patients with heart failure,
_RENITEC _
will help the heart to
function better.
You have high blood pressure or
hypertension if your blood pressure
stays high even when you are calm
and relaxed. High blood pressure
develops when the blood vessels
tighten, making it

Ciri produk

RENITEC
(enalapril maleate/enalaprilat)
[Tablets]
S-LPC-OG0421-MF-102020-Malaysia
Copyright 2021 Organon group of companies. All rights reserved.
LOCAL PHYSICIANS CIRCULAR
Tablets
RENITEC®
Oral (enalapril maleate)
RENITEC
®
(enalapril maleate) is the maleate salt of enalapril, a derivative of
two amino-acids,
L-alanine and L-proline. Following oral administration, enalapril is
rapidly absorbed and then
hydrolyzed to enalaprilat, which is a highly specific, long-acting,
non-sulphydryl angiotensin
converting enzyme inhibitor.
RENITEC
is
indicated
in
the
treatment
of
all
grades
of
essential
hypertension,
and
in
renovascular hypertension. It may be used alone as initial therapy or
concomitantly with other
antihypertensive agents, especially diuretics.
RENITEC is also indicated in the treatment and prevention of heart
failure.
A multicenter, placebo-controlled, double-blind study of left
ventricular dysfunction (SOLVD)
assessed
the
effects
of
RENITEC
in
6,797
patients.
2,569
patients
with
all
degrees
of
symptomatic heart failure (primarily mild to moderate New York Heart
Association Class II and
III) were randomized into the Treatment Arm, and 4,228 patients with
asymptomatic left
ventricular
dysfunction
were
randomized
into
the
Prevention
Arm.
The
combined
results
demonstrated an overall reduced risk for the development of major
ischemic events. RENITEC
decreased the incidence of myocardial infarction and reduced the
number of hospitalizations for
unstable angina pectoris in patients with left ventricular
dysfunction.
In addition, in the Prevention Arm, RENITEC significantly prevented
the development of
symptomatic heart failure and reduced the number of hospitalizations
for heart failure. In the
Treatment Arm, RENITEC, as an adjunct to conventional therapy,
significantly reduced overall
mortality and hospitalization for heart failure and improved NYHA
functional class.
In a similar study involving 253 patients with severe heart failure
(New York Heart Association
Class IV), RENITEC was shown to improve symptoms an