Prima Monensin 20% (ww)Granules

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

MONENSIN SODIUM

Boleh didapati daripada:

Prima Inter-chem Sdn. Bhd.

INN (Nama Antarabangsa):

MONENSIN SODIUM

Unit dalam pakej:

25 kg

Dikeluarkan oleh:

Shandong Qilu King-Phar Pharmaceutical Co., Ltd

Ciri produk

PRIMA MONENSIN 20% (W/W)GRANULES
COMPOSITION: Each kg contains 200g Monensin (as Sodium)
PRODUCT DESCRIPTION: Grey or taupe granule
PHARMACODYNAMICS:
Monensin is a mixture of four analogues, A, B, C and D, with monensin
A being
the major component (98%). Monensin is mainly effective against
gram-positive bacteria. Monensin
acts via complexation of monovalent cations. Its lipophilic structure
facilitates transport of cations
through biological membranes altering normal concentration gradients
PHARMACOKINETICS: Monensin is rapidly absorbed and extensively
metabolized, mainly in liver.
Monensin and its metabolites were shown to be predominantly excreted
in the bile. Orally dosed
radioactivity was nearly completely recovered in faeces, whereas
urinary excretion was negligible in
cattle and rats.
INDICATION
Broiler chickens
As an aid in the prevention of coccidiosis caused by E. necatrix, E.
tenella, E. acervulina, E. brunetti,
E. mivati, and E. maxima.
Replacement chickens intended for use as cage layers
As an aid in the prevention of coccidiosis caused by E. necatrix, E.
tenella, E. acervulina, E. brunetti,
E. mivati, and E. maxima.
RECOMMENDED DOSE RATES ARE AS FOLLOWS
Poultry (Broiler chickens and layer replacement chickens):
99.2-121g/tonne equivalent to 496- 605g Prima Monensin 20 % (w/w)
Granules /tonne of feed
Must be thoroughly mixed in feed before use.
CONTRAINDICATIONS
Do not feed to laying chickens.
Do not feed to chickens over 16 weeks of age.
Do not allow horses, other equines, mature turkeys, or guinea fowl
access to feed containing
monensin. Ingestion of monensin by horses and guinea fowl has been
fatal.
Not for replacement chickens intended to become broiler breeding
chickens
INTERACTIONS WITH OTHER MEDICAMENTS
Not known
SIDE EFFECTS
Not known
SYMPTOMS AND TREATMENT OF OVERDOSE
Not known
WARNINGS AND PRECAUTIONS:
SPECIAL WARNINGS
(i) Must be thoroughly mixed in feeds before use.
(ii) Do not feed undiluted.
(iii) In the absence of coccidiosis in broiler chickens the use of
monensin with no withdrawal
p