Oroplus Gel

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

CHLORHEXIDINE HCL; TRIAMCINOLONE ACETONIDE; LIDOCAINE HYDROCHLORIDE MONOHYDRATE

Boleh didapati daripada:

WINWA MEDICAL SDN. BHD.

INN (Nama Antarabangsa):

CHLORHEXIDINE HCL; TRIAMCINOLONE ACETONIDE; LIDOCAINE HYDROCHLORIDE MONOHYDRATE

Unit dalam pakej:

1 x 8 gm

Dikeluarkan oleh:

WINWA MEDICAL SDN. BHD.

Risalah maklumat

(RiMUP)
Oroplus Gel
Lidocaine, Triamcinolone Acetonide, Chlorhexidine Hydrochloride
(2.5%w/w, 0.1%w/w, 0.5%w/w)
1
What is in the leaflet
1. What Oroplus Gel is used for
2. How Oroplus Gel works
3. Before you use Oroplus Gel
4. How to take Oroplus Gel
5. While you are using it
6. Side Effects
7. Storage and Disposal of Oroplus Gel
8. Product Description
9.
Manufacturer
and
product
registration
holder
10. Date of revision
What Oroplus Gel is used for
Oroplus Gel is an anaesthetic, antibacterial
and anti-inflammatory agent, which is used in
mouth infections or oral lesions. It heals and
relieves
pain
and
discomfort
in
acute
and
chronic lesions of the gum, palate, cheek and
tongue.
How Oroplus Gel works
Lidocaine
is
a
useful
surface
anaesthetic,
rapidly absorbed through mucous membranes
to stop pain and inflammation within a few
minutes.
Triamcinolone Acetonide is a corticosteroid
which works to reduce redness and swelling
of damaged tissues.
Chlorhexidine
has
a
broad-spectrum
of
activity
against
gram
positive
and
gram-
negative bacteria.
Before you use Oroplus Gel
- When you must not take it
Do not take this product if you are allergic
(hypersensitivity)
to
Lidocaine
Hydrochloride,
Triamcinolone
Acetonide,
Chlorhexidine
Hydrochloride
and
its
derivatives.
Talk to your pharmacist or doctor if you are
not sure whether you should start taking this
medicine.
- Before you start to use it
Tell your pharmacist or doctor if you have
allergies to any other medicines.
- Taking other medicines
Do not use any other product on the affected
area without consulting your doctor.
Lidocaine
when
used
in
large
quantities,
repeatedly
or
swallowed
is
systemically
absorbed and interacted with beta-adrenergic
blocking agents, cimetidine and other amide
local
anaesthetic-derivative
antiarrhythmic
agents.
Long term administration of enzyme-inducing
agents such as phenytoin may increase dosage
requirements of Lidocaine.
How to take Oroplus Gel
- How much to take
Apply a small dab to the lesion 3 to 4
times daily after meals and at bedtime.
-

Ciri produk

Active Ingredients:
Lidocaine ................................... 2.5%w/w
Triamcinolone Acetonide ........... 0.1%w/w
Chlorhexidine Hydrochloride ….. 0.5%w/w
Presentation:
Tube of 8g.
Product Descriptions:
White to off white opaque gel with menthol flavour.
Pharmacology:
Lidocaine is a local anaesthetic of the amide type and used to block
nerves
from sending messages to the brain. It has a rapid onset of action and
anaesthesia is obtained within a few minutes. It has an intermediate
duration
of action. Lidocaine is a useful surface anaesthetic, it may be
rapidly and
extensively
absorbed
through
mucous
membranes
following
topical
application to stop pain and inflammation.
Triamcinolone Acetonide is a corticosteroid with mainly glucocorticoid
activity
in anti-inflammatory to reduce redness and swelling of damaged
tissues.
Chlorhexidine is a very potent cationic chemoprophylactic agent that
has a
broad-spectrum of activity against gram positive and gram negative
bacteria. It
is both bacteriostatic and bactericidal depending on its
concentration. The
bactericidal effect, which is achieved at high concentrations, is due
to the
binding
of
the
cationic
to
negatively
charged
bacterial
cell
walls
and
extramicrobial
complexes.
Bacteriostatic
effect
is
achieved
at
low
concentrations which causes an alteration of bacterial cell osmotic
equilibrium
and leakage of potassium and phosphorus.
Lidocaine is readily absorbed through damaged skin and from mucous
membranes. Lidocaine is largely metabolized in the liver and about 90%
is
dealkylated to form monoethylglycinexylidine and glycinexylidine.
Further
metabolism occurs and metabolites are excreted in the urine with less
than
10% of unchanged Lidocaine.
Corticosteroids
are
readily
absorbed
from
the
gastrointestinal
tract.
Triamcinolone is reported to have a half-life in plasma of about 2 to
over 5
hours.
It
is
bound
to
plasma
albumin
to
a
much
smaller
extent
than
hydrocortisone.
Chlorhexidine is poorly absorbed from gastrointestinal tract and skin.
Indications:
Oroplus Gel is