Lacphavid Oral Solution 3.35g5ml

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Lactulose

Boleh didapati daripada:

HOVID BERHAD

INN (Nama Antarabangsa):

Lactulose

Unit dalam pakej:

100 ml; 120 ml; 200 ml; 60 ml; 100 ml

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
_ _
LACPHAVID ORAL SOLUTION 3.35G/5ML
_ _
Lactulose Solution (3.35g/5ml)
Page 1 of 3
WHAT IS IN THIS LEAFLET
1.
What
Lacphavid
Oral
Solution
3.35g/5ml is used for
2.
How
Lacphavid
Oral
Solution
3.35g/5ml works
3.
Before you use Lacphavid Oral
Solution 3.35g/5ml
4.
How
to
use
Lacphavid
Oral
Solution 3.35g/5ml
5.
While you are using Lacphavid
Oral Solution 3.35g/5ml
6.
Side effects
7.
Storage
and
Disposal
of
Lacphavid
Oral
Solution
3.35g/5ml
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT
LACPHAVID
ORAL
SOLUTION
3.35G/5ML IS USED FOR
Lacphavid
is
used
to
treat
constipation
(infrequent
bowel
movements, hard and dry stools) and
used when soft stool is considered of
medical benefit (haemorrhoids, post
colonic/anal
surgery).
Lacphavid
is
also used to treat and prevent hepatic
coma
or
precoma
in
hepatic
encephalopathy
patient
(a
liver
disease
causing
confusion,
tremor,
and
decreased
level
of
consciousness).
HOW
LACPHAVID
ORAL
SOLUTION
3.35G/5ML WORKS
Lacphavid contains a laxative called
lactulose.
It
makes
the
stool
softer
and easier to pass, by drawing water
into the bowel. It is not absorbed into
your body.
BEFORE
YOU
USE
LACPHAVID
ORAL
SOLUTION 3.35G/5ML
_- When you must not use it _
Do not take Lacphavid if:
•
You are allergic (hypersensitive)
to lactulose
•
You have a rare problem called
'galactosaemia'
(a
metabolic
disorder
that
affects
an
individual's ability to metabolize
the sugar galactose properly).
•
You have a blockage caused by
anything
else
but
normal
constipation,
digestive
perforation or risk
of
digestive
perforation.
If
you
are
not
sure
whether
you
should start taking this medicine, talk
to your doctor or pharmacist before
taking Lacphavid.
_ _
_- Before you start to use it _
Talk
to
your
doctor
or
pharmacist
before taking Lacphavid if you suffer
from
any
medical
conditions
or
illnesses, in particular:
•
if you suffer from unexplained
tummy ache
•
if you are unable to digest milk
sugar (lactose

Ciri produk

VILACxx-0 (MY)
LACPHAVID ORAL SOLUTION 3.35G / 5ML
DESCRIPTION
A clear, viscous, colourless to pale brownish-yellow liquid.
COMPOSITION
Each 5 ml contains: Lactulose 3.35g
PHARMACODYNAMICS
Lactulose is broken down in the colon by colonic bacteria into
low molecular organic acids. These acids lowers the pH in the
colonic lumen and increases the volume of colonic contents via
an osmotic effect. These effects stimulates the peristalsis of the
colon and return the consistency of the stool. The constipation is
cleared and the physiological rhythm of the colon is reinstated.
In hepatic encephalopathy (HE), the effect has been attributed
to the suppression of proteolytic bacteria by an increase of
acidophilic bacteria (e.g. lactobacillus), trapping of ammonia in
the ionic form by acidification of the colonic contents, catharsis
due to the low pH in the colon as well as an osmotic effect and
alteration of the bacterial nitrogen metabolism by stimulating the
bacteria to utilize ammonia for bacterial protein synthesis.
PHARMACOKINETICS
Lactulose is poorly absorbed after oral administration and it
would reach the colon unchanged. In the colon, lactulose is
then
metabolised
by
the
colonic
bacterial.
Metabolism
is
complete at doses up to 25-50 g or 40-75 ml; at higher
dosages, a proportion may be excreted unchanged.
INDICATION
•
Constipation: regulation of the colonic physiological rhythm
•
When
soft
stool
is
considered
of
medical
benefit
(haemorrhoids, post colonic / anal surgery)
•
Hepatic encephalopathy (HE): treatment and prevention of
hepatic coma or precoma
CONTRAINDICATIONS
Lacphavid is contraindicated to those who has:
•
Hypersensitivity to the active substance, Lactulose.
•
Galactosaemia
•
Gastro-intestinal obstruction, digestive perforation or risk of
digestive perforation.
WARNINGS AND PRECAUTIONS
•
Painful abdominal symptoms of undetermined cause should
be
evaluated
to
exclude
undiagnosed
perforation
or
obstruction or undiagnosed disease/condition that predisposes
to either before the treatment with