HYOSUN SYRUP

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

HYOSCINE BUTYLBROMIDE

Boleh didapati daripada:

SUNWARD PHARMACEUTICAL SDN. BHD.

INN (Nama Antarabangsa):

HYOSCINE BUTYLBROMIDE

Unit dalam pakej:

120 ml; 100 ml; 60 ml; 120 ml; 100 ml; 60 ml; 3800 ml; 3600 ml; 1000 ml

Dikeluarkan oleh:

SUNWARD PHARMACEUTICAL SDN. BHD.

Risalah maklumat

HYOSUN SYRUP
Hyoscine N- Butylbromide (5mg / 5ml)
1
_ CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET
1. What Hyosun Syrup is used for
2. How Hyosun Syrup works
3. Before you use Hyosun Syrup
4. How to use Hyosun Syrup
5. While you are using it
6. Side effects
7. Storage and disposal of Hyosun Syrup
8. Product description
9. Manufacturer and Product Registration
Holder
10. Date of revision
WHAT HYOSUN SYRUP IS USED FOR
Hyosun Syrup is used for relief spasm and
increased movement of gastrointestinal, gall
bladder
and
urinary
tract.
It
also
used
to
relieve painful menstruation.
HOW HYOSUN SYRUP WORKS
The active ingredient in the medicine is
Hyoscine. The effect of Hyoscine on the
heart
is
to
alter
heart
rate.
With
small
doses, the heart rate decreases temporarily
and
increases
with
larger
doses.
It
also
reduces
the
movement
and
tone
of
the
gastrointestinal tract and may even reduce
the volume of its various secretions.
BEFORE YOU USE HYOSUN SYRUP
_- When you must not use it _
Do not use Hyosun Syrup if you:

hypersensitive to hyoscine or any of the
other ingredients listed at the end of this
leaflet

have increased pressure in the eye, esopha-
gus (food tube) disorder, prostate enlarge-
ment or obstruction of the bladder neck

have muscle weakness.
_ _
_- Before you start to use it _
You should check with your doctor if you :-

have gastric outlet obstruction.

are elderly person.

have metabolic, kidney or liver problem.

are pregnant, plan to become pregnant,
breast-feeding or intend to breast feed.
_- Taking other medicines _
There are few medicines which may interact
with Hyosun Syrup. It is important to tell
your doctor or pharmacist about all the medi-
cines that you are taking including those
obtained without doctor’s prescription.
You should talk to your doctor or pharmacist
if you are taking on the following medicines:-

Tricyclic
anti-depressants,
for
depression
treatment.

Antihistamines, treatment to relieve
symptoms of different types of allergies.

Ciri produk

PRODUCT DESCRIPTION:
A clear, red syrup with cherry flavour.
PHARMACODYNAMICS:
The effect of Hyoscine on the heart is to alter rate. With small
doses, the heart rate
decreases temporarily and increases with larger doses. It also reduces
the motility and tone
of the gastrointestinal tract and may even reduce the volume of its
various secretions. The
drug will produce mydriasis and paralysis of accommodation
(cyclopegia).
PHARMACOKINETICS:
Hyoscine butylbromide is poorly absorbed from the gastrointestinal
tract. In 10 experiments
in 3 volunteers, hyoscine butylbromide in single doses of up to 600mg
taken as tablets,
appeared to be inactive by mouth, either it remained unabsorbed or it
was absorbed more
slowly than it was inactivated in the body.
After 50 to 100mg of hyoscine butylbromide was given to 6 male
volunteers, by mouth or by
intra-intestinal infusion, a very little hyoscine butylbromide was
absorbed from the upper
small intestinal and none appeared in the plasma.
INDICATION:
It is indicated for gastrointestinal spasm and hypermotility, biliary
dyskinesia and spasm of
the urinary tract, delayed relaxation of the lower uterine segment and
dysmenorrhea.
RECOMMENDED DOSAGE:
Adults: 10ml to 20ml, three to four times daily.
Children (6 - 12 years): 10ml three times daily.
The doses are to be taken half an hour before meals.
ROUTE OF ADMINISTRATION: Oral
CONTRAINDICATIONS:
Because of the anti-cholinergic effect of hyoscine, it should not be
used in patients with
glaucoma, achalasia, prostatic hypertrophy, or obstruction of the
bladder neck. It is also
contraindicated
in
patients
with
myasthenia
gravis
and
in
patients
known
to
be
hypersensitive to hyoscine.
WARNINGS AND PRECAUTIONS:
Since drowsiness, disorientation and confusion may occur with the use
of hyoscine,
patients should be warned of the possibility and cautioned against
engaging in activities
that require mental alertness, such as driving a motor vehicle or
operating dangerous
machinery. Potentially alarming idiosyncratic reactions may occur with
ordinar