hovid-Paracetamol Suspension 250mg5ml (Sugar Free)

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Paracetamol

Boleh didapati daripada:

HOVID BERHAD

INN (Nama Antarabangsa):

Paracetamol

Unit dalam pakej:

120ml mL; 60ml mL

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP) _
HOVID-PARACETAMOL SUSPENSION
250MG/5ML (SUGAR FREE)
Paracetamol (250 mg in 5 ml)
1
WHAT IS IN THIS LEAFLET
1.
What
Hovid-Paracetamol
Suspension is used for
2.
How
Hovid-Paracetamol
Suspension works
3.
Before you use Hovid-Paracetamol
Suspension
4.
How
to
use
Hovid-Paracetamol
Suspension
5.
While you are using Paracetamol
Syrup
6.
Side effects
7.
Storage
and
Disposal
of
Paracetamol Syrup
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
11.
Serial Number
WHAT HOVID-PARACETAMOL SUSPENSION
IS USED FOR
Hovid-Paracetamol Suspension is used
to relief fever, headache and symptoms
of colds and flu, toothache, discomfort
of teething and fever after vaccination.
HOW HOVID-PARACETAMOL SUSPENSION
WORKS
Hovid-Paracetamol
Suspension
contains
Paracetamol
that
helps
to
block pain stimulation and it acts on
heat-regulating
center
in
brain.
This
results
in
increase
in
blood
flow
through skin, sweating and heat loss.
BEFORE
YOU
USE
HOVID-PARACETAMOL
SUSPENSION
_ _
_- When you must not use it _
Do not take this medicine if:
•
You
have
ever
had
an
allergic
reaction to paracetamol.
•
You have severe and active liver
impairment.
This
preparation
contains
PARACETAMOL.
Do
not
take
any
other paracetamol containing medicines
at the same time.
If you are not sure whether you should
start taking this medicine, talk to your
pharmacist or doctor.
_- Before you start to use it _
Tell your doctor if you are taking or
have
recently
taken
any
other
medicines,
including
medicines
obtained without a prescription, as they
may
interact
with
Hovid-Paracetamol
Suspension.
Allergy alert: Paracetamol may cause
severe skin reactions. Symptoms may
include skin reddening, blisters or rash.
These
could
be
signs
of
a
serious
condition. If these reactions occur, stop
use and seek medical assistance right
away.
_ _
_- Taking other medicines_
The
use
of
anti-psychotic
medicines
such
as
barbiturate,
tricyclic
antidepressants
and
alcohol
may
increase
liver
toxicity
of
t

Ciri produk

DESCRIPTION
Pink, viscous suspension with raspberry flavour.
COMPOSITION
Each 5 ml contains:
Paracetamol 250 mg
ACTIONS AND PHARMACOLOGY
Paracetamol is a centrally acting analgesic and antipyretic
with minimal anti-inflammatory properties.
ANALGESIC:
The mechanism of analgesic action has not been fully
determined.
Paracetamol
may
act
predominantly
by
inhibiting prostaglandin synthesis in the central nervous
system (specifically cyclooxygenase (COX)-2) and, to a
lesser
extent,
through
a
peripheral
action
by
blocking
pain-impulse generation.
The peripheral action may also be due to inhibition of
prostaglandin synthesis or to inhibition of the synthesis or
actions of other substances that sensitize pain receptors to
mechanical or chemical stimulation.
ANTIPYRETIC:
Paracetamol
act
centrally
on
the
hypothalamic
heat-regulating center to produce peripheral vasodilatation
resulting in increase blood flow through the skin, sweating
and heat loss. Paracetamol reduces fever by inhibiting the
formulation and release of prostaglandins in the CNS and by
inhibiting
endogenous
pyrogens
at
the
hypothalamic
thermoregulator center.
PHARMACOKINETICS
Following
oral
administration
paracetamol
is
rapidly
absorbed.
Paracetamol absorption takes place mainly in the small
intestine and therefore the rate of absorption is depending
on the rate of gastric emptying. It has been shown that
drugs which delay gastric emptying also delay the absorption
of paracetamol whereas metoclopramide (a drug which
increases
the
rate
of
gastric
emptying)
accelerates
absorption
of
the
analgesic
through
the
total
amount
absorbed doses not increase.
The presence of food in the stomach has also been reported
to reduce the rate of absorption of paracetamol. Alterations
in gastric pH have no appreciable effect on paracetamol
absorption. During absorption, the amount of paracetamol
which is inactivated is negligible and it has been shown that
paracetamol does not affect gastric mucosal permeability
and does not produce mucosal bleeding.
Peak
plasma
concentrations