Country: Amerika Syarikat
Bahasa: Inggeris
Sumber: NLM (National Library of Medicine)
ISOFLURANE (UNII: CYS9AKD70P) (ISOFLURANE - UNII:CYS9AKD70P)
MWI
ISOFLURANE
ISOFLURANE 1 mL in 1 mL
RESPIRATORY (INHALATION)
PRESCRIPTION
Fluriso™ (isoflurane, USP) is used for induction and maintenance of general anesthesia in horses and dogs. Fluriso™ (isoflurane, USP) is contraindicated in horses and dogs with known sensitivity to isoflurane or to other halogenated agents.
Fluriso™ (isoflurane, USP) is packaged in 100 mL and 250 mL amber-colored bottles. 100 ml - NDC 13985-046-40 250 ml - NDC 13985-046-60
Abbreviated New Animal Drug Application
FLURISO- ISOFLURANE INHALANT MWI ---------- 03-A953/R3 5260-04-14 5260-04-15 FLURIS O (ISOFLURANE, USP) LIQUID FOR INHALATION WARNING: NOT FOR USE IN HORSES INTENDED FOR FOOD. INHALATION ANESTHETIC FOR USE IN HORSES AND DOGS CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. DESCRIPTION: Fluriso (isoflurane, USP) is a nonflammable, nonexplosive general inhalation anesthetic agent. Its chemical name is 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, and its structural formula is: Each mL contains 99.9% isoflurane. ™ ™ Isoflurane is a clear, colorless, stable liquid containing no additives or chemical stabilizers. Isoflurane has a mildly pungent, musty, ethereal odor. Samples stored in indirect sunlight in clear, colorless glass for five years, as well as samples directly exposed for 30 hours to a 2 amp,115 volt, 60 cycle long wave U.V. light were unchanged in composition as determined by gas chromatography. Isoflurane in one normal sodium methoxide-methanol solution, a strong base, for over six months consumed essentially no alkali, indicative of strong base stability. Isoflurane does not decompose in the presence of soda lime (at normal operating temperatures) and does not attack aluminum, tin, brass, iron or copper. CLINICAL PHARMACOLOGY: Fluriso (isoflurane, USP) is an inhalation anesthetic. Induction and recovery from anesthesia with isoflurane are rapid. The level of anesthesia may be changed rapidly with isoflurane. Isoflurane is a profound respiratory depressant. RESPIRATION MUST BE MONITORED CLOSELY IN THE HORSE AND DOG AND SUPPORTED WHEN NECESSARY. As anesthetic dose is increased, both ™ 2,5 3,6 tidal volume and respiratory rate decrease. This depression is partially reversed by surgical stimulation, even at deeper levels of anesthesia. Blood pressure decreases with induction of anesthesia but returns toward normal with surgical stimulation. Progressive increases in depth of anesthesia produce corresponding decreases in blood pressure; however, heart r Baca dokumen lengkap