Flucor Night PE Soft Gelatin Capsule

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

CHLORPHENIRAMINE MALEATE; Paracetamol; PHENYLEPHRINE HYDROCHLORIDE

Boleh didapati daripada:

HOVID BERHAD

INN (Nama Antarabangsa):

CHLORPHENIRAMINE MALEATE; Paracetamol; PHENYLEPHRINE HYDROCHLORIDE

Unit dalam pakej:

8capsule Capsules

Dikeluarkan oleh:

HOVID BERHAD

Risalah maklumat

_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
1
FLUCOR NIGHT PE SOFT GELATIN CAPSULE
_Paracetamol (250 mg), Phenylephrine HCl (5 mg) and Chlorpheniramine
maleate (2 mg) _
_ _
_ _
WHAT IS IN THIS LEAFLET?
1.
What Flucor Night PE Soft Gelatin
Capsule is used for
2.
How Flucor Night PE Soft Gelatin
Capsule works
3.
Before you use Flucor Night PE Soft
Gelatin Capsule
4.
How to take Flucor Night PE Soft
Gelatin Capsule
5.
While you are using Flucor Night
PE Soft Gelatin Capsule
6.
Side effects
7.
Storage
and
Disposal
of
Flucor
Night PE Soft Gelatin Capsule
8.
Product description
9.
Manufacturer
and
Product
Registration Holder
10.
Date of revision
WHAT FLUCOR NIGHT PE SOFT GELATIN
CAPSULE IS USED FOR
Used to temporary relieve running nose
and sneezing, minor aches and pains,
headaches, fever and nasal congestion
associated with the common cold.
HOW
FLUCOR
NIGHT
PE
SOFT
GELATIN
CAPSULE WORKS
Paracetamol relieves pain by blocking
the pain messages from getting through
to the brain. It also acts in the brain to
reduce fever.
Phenylephrine hydrochloride acts as a
decongestant by clearing the nose, nasal
passages and sinuses so that it is easier to
breathe. It narrows the blood vessels in
the affected areas.
Chlorpheniramine
maleate
is
sedating
anti-histamine that gives a drying effect
on the nasal mucosa. The nasal mucosa
is a moist tissue that produces mucus (a
thick slippery substance) in the nose.
BEFORE YOU USE FLUCOR NIGHT PE SOFT
GELATIN CAPSULE
_- When you must not use it _
Do not take this medicine if:

you
are
allergic
to
paracetamol,
phenylephrine
hydrochloride,
chlorpheniramine maleate and any
of the excipients

you have taken monoamine oxidase
inhibitors
in
the
last
14
days
or
within 14 days of stopping it

you have very high blood pressure
or coronary heart disease

you are taking any other medicine
that contains paracetamol

you are pregnant or breastfeeding.
_- Before you start to use it _
_ _
Tell your doctor if:

you have asthma, bronchitis or a
chronic lung disorder

you
are
breas

Ciri produk

This
preparation
contains
PARACETAMOL. Do not take any
other
paracetamol
containing
medicines at the same time.
655
FLUCOR NIGHT PE SOFT GELATIN CAPSULE
WIFLU07-var (MY)
DESCRIPTION
Oblong-shaped,
green
transparent
soft
gelatin capsule printed with "Flucor PE",
filled with transparent green liquid.
COMPOSITION
Each soft gelatin capsule contains:
Paracetamol
250.0 mg
Phenylephrine HC
_l _
5.0 mg
Chlorpheniramine maleate
2.0 mg
ACTIONS AND PHARMACOLOGY
Paracetamol,
as
an
analgesic,
may
act
predominantly
by
inhibiting
prostaglandin
synthesis
in
the
central
nervous
system
(CNS) and, to a lesser extent, through a
peripheral action by blocking pain-impulse
generation. The peripheral action may also
be
due
to
inhibition
of
prostaglandin
synthesis or to inhibition of the synthesis or
actions of other substances that sensitize
pain receptors to mechanical or chemical
stimulation. Paracetamol probably produces
antipyresis
by
acting
centrally
on
the
hypothalamic
heat-regulating
center
to
produce peripheral vasodilation resulting in
increased
blood
flow
through
the
skin,
sweating, and heat loss. The central action
probably involves inhibition of prostaglandin
synthesis in the hypothalamus.
Phenylephrine
hydrochloride
is
a
sympathomimetic with mainly direct effects
on
adrenergic
receptors.
It
has
predominantly alpha-adrenergic activity and
is without significant stimulating effects on
the
CNS
at
usual
dose.
Following
oral
administration
or
topical
application
of
phenylephrine to the mucosa, constriction of
blood vessels in the nasal mucosa relieves
nasal congestion associated with allergy or
head colds.
Chlorpheniramine
maleate
is
a
sedating
antihistamine
that
causes
a
moderate
degree
of
sedation.
Its
anticholinergic
actions provide a drying effect on the nasal
mucosa.
PHARMACOKINETICS
Paracetamol is readily absorbed from the
gastrointestinal
tract
with
peak
plasma
concentrations occurring about 10 to 60
minutes
after
oral
administration
and
is
distributed
into
most
body
tissues.
The
elimination half-life of paracetamol varie