DYNA ERYTHROMYCIN TABLET

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ERYTHROMYCIN STEARATE

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

ERYTHROMYCIN STEARATE

Unit dalam pakej:

1000 Tablet Tablets

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA ERYTHROMYCIN TABLET
Erythromycin Stearate (250 mg)
Page 1
What is in this leaflet
1.
What Dyna Erythromycin Tablet is
used for
2.
How
Dyna
Erythromycin
Tablet
works
3.
Before you use Dyna Erythromycin
Tablet
4.
How
to
use
Dyna
Erythromycin
Tablet
5.
While you are using it
6.
Side effects
7.
Storage
and
Disposal
of
Dyna
Erythromycin Tablet
8.
Product Description
9.
Manufacturer
and
Product
Registration Holder
10. Date of revision
What Dyna Erythromycin Tablet is
used for
Dyna Erythromycin Tablet is used in
treatment of
- Respiratory tract infection.
- Ear and eye infections.
- Gastrointestinal infection.
- Skin and soft tissue infections.
- Gonorrhoea
/
syphilis
(sexually
transmitted infection)
- Whooping cough.
How
Dyna
Erythromycin
Tablet
works
Erythromycin is a macrolide antibiotic.
It works by killing bacteria which cause
infections.
Before you use Dyna Erythromycin
Tablet
- When you must not use it
Do not take Dyna Erythromycin Tablet
if:
- you are allergic to Erythromycin or
any other ingredients of this medicine
(listed in Product Description)
- you are taking astemizole, terfenadine
(used to treat allergic inflammatory
conditions)
- Before you start use it
Pregnancy and lactation
Please
consult
your
doctor
or
pharmacist
if
you
are
pregnant,
planning for pregnancy or breastfeeding
before using any medicine.
Erythromycin is secreted into the breast
milk.
Please
consult
your
doctor
or
pharmacist
before
taking
Dyna
Erythromycin while breastfeeding.
Tell your doctor if you have:
- Impaired liver function
- Heart rhythm disorder
- Hearing impairment or problems
- Taking other medicines
Tell your doctor if you are taking:
- Astemizole, terfenadine (medicine to
treat
allergic
inflammatory
conditions)
- Digoxin
(medicine
to
treat
heart
rythym disorder)
- Ergotamine
(medicine
to
treat
migraine)
- Penicillin,
lincomycin,
methenamine
(antibiotics)
- Lovastatin
(medicine
to
lower
cholesterol level)
- Alfentanil (medicine to relieve pain)
- Blood thinning agent
- Hyda

Ciri produk

DYNA ERYTHROMYCIN TABLET
MAL19962105AZ
DESCRIPTION:
TABLET
Colour
:
Pink
Shape
:
Round / Biconvex
Coating :
Film-coated
EACH TABLET CONTAINS:
Erythromycin Stearate ∗ 420 mg equivalent to Erythromycin
.................. 250 mg
∗ Approximate potency equivalent to not less than 600 µg of
Erythromycin per mg.
PHARMACODYNAMICS:
Erythromycin is a macrolide antibiotic. It interferes with bacterial
protein synthesis by binding to the 50S subunit of
ribosomes. It is bacteriostatic or bactericidal depending on its
concentration and the type of organism. Activity increases
with increases in pH up to about pH 8.5. The minimum inhibitory
concentrations of Erythromycin for sensitive micro-
organisms have been reported to range from less than 0.1 to about 2
µg per ml.
PHARMACOKINETICS:
Erythromycin base is unstable in gastric acid and food may reduce the
absorption of the base or the stearate. After
absorption,
Erythromycin
diffuses
readily
into
most
body
fluids.
In
the
absence
of
meningeal
inflammation,
low
concentrations are normally achieved in the spinal fluid but passage
of the drug across the blood-brain-barrier increases in
meningitis. In the presence of normal hepatic function, Erythromycin
is concentrated in the liver and excreted in the bile;
the effect of hepatic dysfunction on excretion of Erythromycin by the
liver into the bile is not known. After oral
administration, < 5% of the activity of the administered dose can be
recovered in the urine. Erythromycin crosses the
placental barrier but foetal plasma levels are low.
INDICATION:
Upper and lower respiratory tract infection, ear and eye infections,
gastrointestinal, skin and soft tissue infections.
Gonorrhoea, Syphilis and Whooping cough.
RECOMMENDED DOSAGE:
Adults: Usual dose: 250 mg 4 times daily. Dosage may be increased up
to 4 g/day according to the severity of the infection.
Children: 30-50 mg/kg/day, in divided doses. For more severe
infections, this dose may be doubled.
Optimum serum levels of Erythromycin may be reached if taken in the
fasting state o