Dyna Cloxacillin Capsule 500mg

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

CLOXACILLIN SODIUM

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

CLOXACILLIN SODIUM

Unit dalam pakej:

100 Capsule Capsules; 500 Capsule Capsules

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA CLOXACILLIN CAPSULE
Cloxacillin Sodium (250mg, 500mg)
Page 1 of 2
What is in this leaflet
1.
What Dyna Cloxacillin Capsule is
used for
2.
How Dyna Cloxacillin Capsule
works
3.
Before you use Dyna Cloxacillin
Capsule
4.
How to use Dyna Cloxacillin
Capsule
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of Dyna
Cloxacillin Capsule
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What Dyna Cloxacillin Capsule is
used for
Dyna Cloxacillin Capsule is used to
treat infections caused by resistant
bacteria, including
- Infections of skin and soft tissues
- Bones and joints
- Respiratory tract and urinary tract
- Otitis media
- Inflammation on the heart's inner
lining
- Blood poisoning
- Inflammation of the membranes
surrounding brain and spinal cord.
How Dyna Cloxacillin Capsule works
Cloxacillin is a bactericidal antibiotic
which inhibits bacterial cell wall
synthesis.
Before you use Dyna Cloxacillin
Capsule
- When you must not use it
Do not take Dyna Cloxacillin Capsule
if you have hypersensitive to
Cloxacillin or a history of allergic to
Penicillin group of drugs.
If a skin rash occurs, treatment should
be discontinued.
Pregnancy and lactation
Do not take Dyna Cloxacillin Capsule
if you are pregnant, trying to get
pregnant or think you may be pregnant.
Do not take Dyna Cloxacillin Capsule
if you are breast-feeding. Ask your
doctor or pharmacist for advice before
taking any medicine.
- Before you start use it
Tell your doctor if you have impaired
kidney function, hypersensitive to any
other Penicillin or Cephalosporin or
Penicillamine.
- Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescription from a
pharmacy, supermarket or health food
shop.
Probenecid impairs kidney excretion
and reduces anticoagulant effect.
How to use Dyna Cloxacillin Capsule
- How much to use
Adult: 250 – 500 mg every 6 hours
daily.
Children: 50-100 mg per kg bod

Ciri produk

DYNA CLOXACILLIN CAPSULE
DESCRIPTION
CONTENT
DYNA CLOXACILLIN CAPSULE 250MG
MAL19930225AZ
CAPSULE
Capsule Colour
:
Medium Orange/Black
Capsule Size
:
# 2
Granules Colour
:
White
Each capsule contains:
Cloxacillin Sodium equivalent to Cloxacillin 250 mg
DYNA CLOXACILLIN CAPSULE 500MG
MAL07090901AZ
CAPSULE
Capsule Colour
:
Medium Amethyst/Black
Capsule Size
:
# 0
Granules Colour
:
White
Marking
:
“DYNA” & Logo
Each capsule contains:
Cloxacillin Sodium equivalent to Cloxacillin 500 mg
PHARMACODYNAMICS:
Cloxacillin is a bactericidal antibiotic which inhibits bacterial cell
wall synthesis, probably by acylation of membrane-bound transpeptidase
enzymes. This
prevents cross-linkage of peptidoglycan chains which is necessary for
bacterial cell wall strength and rigidity. Also, cell division and
growth are inhibited and
lysis of susceptible bacteria frequently occurs. Rapidly dividing
bacteria are most susceptible to penicillin group of antibiotics.
Cloxacillin is resistant to
staphylococcal penicillinase. It has an antibacterial spectrum similar
to that of methicillin.
PHARMACOKINETICS:
Cloxacillin sodium is incompletely absorbed from the gastrointestinal
tract after oral administration, and absorption is further reduced by
the presence of
food in the stomach. After an oral dose of 500 mg, a peak plasma
concentration of 7 to 14 g per ml is obtained in fasting subjects
in 1 to 2 hours.
Absorption is more complete when given by intramuscular injection and
peak plasma concentrations of about 15 g per ml have been observed
30 minutes
after a dose of 500 mg. Doubling the dose can double the plasma
concentration. About 94% of cloxacillin in the circulation are bound
to plasma proteins.
Cloxacillin has been reported to have a plasma half-life of
approximately 0.5 hours in healthy subjects. The half-life is
prolonged in neonates. Cloxacillin
diffuses across the placenta into the foetal circulation and is
excreted in breast milk. There is little diffusion into the CFS except
when the meninges are
inflamed. Therapeutic c