DYNA AMPICILLIN CAPSULE 250MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

AMPICILLIN TRIHYDRATE

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

AMPICILLIN TRIHYDRATE

Unit dalam pakej:

1000 Capsules; 1000 Capsules

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA AMPICILLIN CAPSULE
Ampicillin Trihydrate (250 mg, 500 mg)
1
What is in this leaflet
1.
What Dyna Ampicillin Capsule is
used for
2.
How Dyna Ampicillin Capsule
works
3.
Before you use Dyna Ampicillin
Capsule
4.
How to use Dyna Ampicillin
Capsule
5.
While you are using it
6.
Side effects
7.
Storage and disposal of Dyna
Ampicillin Capsule
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What Dyna Ampicillin Capsule used
for
Indicated for the treatment of
infections caused by sensitive
microbes such as:
1.
Ear, nose & throat infections
2.
Lower respiratory tract infections
3.
Urinary tract infections
4.
Skin and soft tissue infections
How Dyna Ampicillin Capsule
works
Ampicillin is a bactericidal antibiotic
which inhibit bacterial cell wall
synthesis. Also, cell division and
growth are inhibited and death of
susceptible bacteria frequently occurs.
Before you use Dyna Ampicillin
Capsule
- When you must not use it
Do not use Dyna Ampicillin Capsule
to individuals hypersensitive to
Ampicillin
Pregnancy and lactation
Do not take Dyna Ampicillin Capsule
if you are pregnant, trying to get
pregnant or think you may be
pregnant.
Do not take Dyna Ampicillin Capsule
if you are breast-feeding
Ask your doctor or pharmacists for
advice before taking Dyna Ampicillin
Capsule
- Before you start use it
Tell your doctor or pharmacist if you
have:
1.
Hypersensitivity to other Penicillin
or Cephalosporin or Penicillamine
2.
Impaired kidney function
- Taking other medicines
Tell your doctor if you are taking
bacteriostatic medicines, oral
contraceptives, Probenecid,
Allopurinol and other medicines,
including any that you buy without a
prescription from a pharmacy,
supermarket or health food shop.
How to use Dyna Ampicillin
Capsule
- How much to use
Adults: 250 - 500 mg every 6 hours up
to 6 g daily
Children up to 20 kg body-weight:
12.5 - 25 mg per kg body-weight every
6 hours
Gonorrhea: 3 g as a single oral dose
may be administered with 1 g
P

Ciri produk

DYNA AMPICILLIN
DESCRIPTION
CONTENT
DYNA AMPICILLIN CAPSULE
250MG
MAL19910018AZ
CAPSULE
Capsule Colour
:
Red/Black
Capsule Size
:
# 2
Granules Colour
:
White
Each capsule contains:
Ampicillin Trihydrate equivalent to
Ampicillin ............................. 250 mg
DYNA AMPICILLIN CAPSULE
500MG
MAL19910019AZ
CAPSULE
Capsule Colour
:
Red/Black
Capsule Size
:
# 0
Granules Colour
:
White
Each capsule contains:
Ampicillin Trihydrate equivalent to
Ampicillin ............................ 500 mg
PHARMACODYNAMICS:
Ampicillin is a bactericidal antibiotic which inhibits bacterial cell
wall synthesis, probably by acylation of membrane-
bound transpeptidase enzymes. This prevents cross-linkage of
peptidoglycan chains which is necessary for bacterial cell
wall strength and rigidity. Also, cell division and growth are
inhibited and lysis of susceptible bacteria frequently occurs.
Rapidly dividing bacteria are most susceptible to penicillin group of
antibiotics including Ampicillin.
PHARMACOKINETICS:
Ampicillin is acid stable and 30 to 60% of an oral dose is absorbed.
Peak serum concentrations of 0.8 to 4 mcg/ml are
attained 1 to 2 hours after oral doses of 125 to 500 mg of anhydrate
or trihydrate. The serum half-life is 1 to 2 hours
which is increased in subjects with renal function impairment.
Ampicillin enters most body cavities, tissues and fluids
except the cerebrospinal fluid unless the meninges are inflamed, in
which case large amounts may be detectable in this
fluid; Ampicillin crosses the placenta and is excreted in the milk;
volume of distribution about 20 L which in subjects
with cirrhosis may reach about 60 L. About 20% of Ampicillin are bound
to plasma proteins. 30% to 50% of an oral dose
is excreted in the urine in 6 to 8 hours; up to 70% is excreted in 24
hours; urinary excretion is decreased after the
administration of Probenecid; Ampicillin is excreted in the bile in
concentrations up to 4 mcg/ml after an oral dose of
125 mg; biliary excretion is increased in subjects with cirrhosis.
INDICATIONS:
Infections caus