Dyna Amoxycillin Capsule 250mg

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

AMOXYCILLIN TRIHYDRATE

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

AMOXYCILLIN TRIHYDRATE

Unit dalam pakej:

1000 Capsules; 100 Capsules

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA AMOXYCILLIN CAPSULE
Amoxycillin Trihydrate (250 mg, 500 mg)
Page 1 of 2
What is in this leaflet
1.
What DYNA AMOXYCILLIN
CAPSULE is used for
2.
How DYNA AMOXYCILLIN
CAPSULE works
3.
Before you use DYNA
AMOXYCILLIN CAPSULE
4.
How to use DYNA AMOXYCILLIN
CAPSULE
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of DYNA
AMOXYCILLIN CAPSULE
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What DYNA AMOXYCILLIN
CAPSULE is used for
DYNA AMOXYCILLIN CAPSULE is
used for
 Infections caused by bacteria
 Ear nose and throat infections
 Chest infections
 Urinary tract infections
 Skin and soft tissue infections
How DYNA AMOXYCILLIN
CAPSULE works
Amoxycillin work by killing the bacteria
that cause infections.
Before you use DYNA
AMOXYCILLIN CAPSULE
- When you must not use it
Not to be use in individuals with known
hypersensitivity to penicillin.
Pregnancy and lactation
Do not take DYNA AMOXYCILLIN
CAPSULE if you are pregnant, trying to
get pregnant or think you may be
pregnant.
Do not take DYNA AMOXYCILLIN
CAPSULE if you are breast-feeding. Ask
your doctor or pharmacist for advice
before taking any medicine.
- Before you start use it
Tell your doctor if:
 You are hypersensitive to other
penicillins or cephalosporins or
penicillamine.
 Impaired kidney function
Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescription from a
pharmacy, supermarket or health food
shop.
Probenecid prolongs blood levels of
amoxycilin. Antacids and other
alkalising agents can impair absorption
of amoxycilin. May reduce effectiveness
of oral contraceptives. Concurrent
administration of amoxycilin and
allopurinol increases incidence of rashes.
How to use DYNA AMOXYCILLIN
CAPSULE
- How much to use
Follow all directions given to you by
your doctor and pharmacist carefully.
They may differ from the information
contained in this leaflet. If you do not
und

Ciri produk

DYNA AMOXYCILLIN CAPSULE
DESCRIPTION
CONTENT
DYNA AMOXYCILLIN CAPSULE
250MG
MAL19930222AZ
CAPSULE
Capsule Colour :
Orange/Red
Capsule Size
:
# 2
Granules Colour:
White To Off-White
Each Capsule Contains:
Amoxycillin Trihydrate Equivalent To
Amoxycillin 250 mg
DYNA AMOXYCILLIN CAPSULE
500MG
MAL19930221AZ
CAPSULE
Capsule Colour :
Orange/Red
Capsule Size
:
# 0
Granules Colour:
White To Off-White
Each Capsule Contains:
Amoxycillin Trihydrate Equivalent To
Amoxycillin 500 mg
PHARMACODYNAMICS:
Amoxycillin is a bactericidal antibiotic which inhibits bacterial cell
wall synthesis, probably by acylation of membrane-bound
transpeptidase enzymes. This prevents cross-linkage of peptidoglycan
chains which is necessary for bacterial cell wall
strength and rigidity. Also, cell division and growth are inhibited
and lysis of susceptible bacteria frequently occurs. Rapidly
dividing bacteria are most susceptible to penicillin group of
antibiotics including Amoxycillin.
PHARMACOKINETICS:
Amoxycillin is stable to gastric acid and 50 to 90 % of a dose is
absorbed after oral administration; absorption is more
complete than that of ampicillin and it is not greatly influenced by
the presence of food. After an oral dose of 500 mg, peak
serum concentrations of 3 to 20 mcg/ml are attained in 1 to 2 hours;
detectable concentrations are present after 8 hours;
peak concentrations occur earlier in children and infants but later in
neonates. Serum half-life is 1 hour which may be
increased to 15 hours in renal failure. After absorption, Amoxycillin
enters most tissues and fluids but it is not detectable in
the cerebrospinal fluid even when the meninges are inflamed; crosses
the placenta and small amounts are secreted in the
milk; volume of distribution at steady-state serum concentrations,
about 0.3 litres/kilogram body-weight; protein binding, 15
to 25 % bound to plasma proteins.
Amoxycillin is metabolised to inactive metabolites and 10 to 25 %
appears to be converted to penicilloic acid. 35 to 45 % is
excreted in the urine after an oral dose a