DYNA AMOXYCILLIN 250MG5ML

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

AMOXYCILLIN

Boleh didapati daripada:

DYNAPHARM (M) SDN BHD

INN (Nama Antarabangsa):

AMOXYCILLIN

Unit dalam pakej:

60ml mL; 100ml mL

Dikeluarkan oleh:

DYNAPHARM (M) SDN BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
DYNA AMOXYCILLIN SUSPENSION
Amoxycillin Trihydrate (125 mg/5 ml, 250 mg/5 ml)
1
What is in this leaflet
1.
What DYNA AMOXYCILLIN is
used for
2.
How DYNA AMOXYCILLIN works
3.
Before you use DYNA
AMOXYCILLIN
4.
How to use DYNA AMOXYCILLIN
5.
While you are using it
6.
Side effects
7.
Storage and Disposal of DYNA
AMOXYCILLIN
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10. Date of revision
What DYNA AMOXYCILLIN is used
for
DYNA AMOXYCILLIN is used for
 Infections caused by bacteria.
 Ear nose and throat infections
 Chest infections.
 Urinary tract infections
 Skin and soft tissue infections.
How DYNA AMOXYCILLIN works
Amoxycillin work by killing the bacteria
that cause infections.
Before you use DYNA
AMOXYCILLIN
- When you must not use it
Not to be use in patients with known
hypersensitivity to penicillin.
Pregnancy and lactation
Do not take DYNA AMOXYCILLIN if
you are pregnant, trying to get pregnant
or think you may be pregnant.
Do not take DYNA AMOXYCILLIN if
you are breast-feeding. Ask your doctor
or pharmacist for advice before taking
any medicine.
- Before you start use it
Tell your doctor if:
 You are hypersensitive to other
penicillins or cephalosporins or
penicillamine.
 Impaired kidney function
- Taking other medicines
Tell your doctor if you are taking any
other medicines, including any that you
buy without a prescription from a
pharmacy, supermarket or health food
shop.
 Probenecid prolongs blood levels of
amoxycilin.
 Antacids and other alkalising agents
can impair absorption of amoxycilin.
 May reduce effectiveness of oral
contraceptives.
 Concurrent administration of
amoxycilin and allopurinol increases
incidence of rashes.
How to use DYNA AMOXYCILLIN
- How much to use
Shake to loosen powder. Add
approximately half the final volume (30
ml or 50 ml) of freshly boiled and cooled
water and shake gently.
Add more water until the final volume
(60 ml or 100 ml) mark is reached and
shake well.
Keep refri

Ciri produk

DYNA AMOXYCILLIN
DESCRIPTION
CONTENT
Dyna Amoxycillin
125mg/5ml
MAL19985981AZ
Dry Syrup
Colour: White
(Pink on adding water)
Flavour: Strawberry
Each 5 ml of the reconstituted suspension contains:
Amoxycillin Trihydrate equivalent to
Amoxycillin
............................................................... 125 mg
Preservative: Sodium Benzoate ............................ 0.1% w/v
Dyna Amoxycillin
250mg/5ml
MAL19985982AZ
Dry Syrup
Colour: White
(Pink on adding water)
Flavour: Strawberry
Each 5 ml of the reconstituted suspension contains:
Amoxycillin Trihydrate equivalent to
Amoxycillin
.............................................................. 250 mg
Preservative: Sodium Benzoate ............................ 0.1% w/v
PHARMACODYNAMICS:
Amoxycillin is a bactericidal antibiotic which inhibits bacterial cell
wall synthesis, probably by acylation of membrane-
bound transpeptidease enzymes. This prevents cross-linkage of
peptidoglycan chains which is necessary for bacterial
cell wall strength and rigidity. Also, cell division and growth are
inhibited and lysis of susceptible bacteria frequently
occurs. Rapidly dividing bacteria are most susceptible to penicillin
group of antibiotics including Amoxycillin.
PHARMACOKINETICS:
Amoxycillin is stable to gastric acid and 50 to 90% of a dose is
absorbed after oral administration; absorption is more
complete than that of Ampicillin and it is not greatly influenced by
the presence of food. After an oral dose of 500 mg,
peak serum concentrations of 3 to 20 mcg/ml are attained in 1 to 2
hours; detectable concentrations are present after
8 hours; peak concentrations occur earlier in children and infants but
later in neonates. Serum half-life is 1 hour which
may be increased to 15 hours in renal failure. After absorption,
Amoxycillin enters most tissues and fluids but it is not
detectable in the cerebrospinal fluid even when the meninges are
inflamed; crosses the placenta and small amounts
are secreted in the milk; volume of distribution at steady-state serum
concentrations, ab