DOXYCYCLINE HYCLATE tablet, film coated

Country: Amerika Syarikat

Bahasa: Inggeris

Sumber: NLM (National Library of Medicine)

Bahan aktif:

DOXYCYCLINE HYCLATE (UNII: 19XTS3T51U) (DOXYCYCLINE ANHYDROUS - UNII:334895S862)

Boleh didapati daripada:

Bryant Ranch Prepack

Laluan pentadbiran:

ORAL

Jenis preskripsi:

PRESCRIPTION DRUG

Tanda-tanda terapeutik:

To reduce the development of drug-resistant bacteria and maintain effectiveness of Doxycycline and other antibacterial drugs, Doxycycline should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Doxycycline is indicated for the treatment of the following infections - Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae. - Respiratory tract infections caused by Mycoplasma pneumoniae. - Lymphogranuloma venereum caused by Chlamydia trachomatis . - Psittacosis (ornithosis) caused by Chlamydophila psittaci . - Trachoma caused by Chlamydia trachomatis , although the infectious agent is not always eliminated, as judg

Ringkasan produk:

Product: 63629-8262 NDC: 63629-8262-1 20 TABLET, FILM COATED in a BOTTLE NDC: 63629-8262-2 30 TABLET, FILM COATED in a BOTTLE NDC: 63629-8262-3 50 TABLET, FILM COATED in a BOTTLE

Status kebenaran:

Abbreviated New Drug Application

Ciri produk

DOXYCYCLINE HYCLATE- DOXYCYCLINE HYCLATE TABLET, FILM COATED
BRYANT RANCH PREPACK
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DOXYCYCLINE HYCLATE CAPSULES, USP
DOXYCYCLINE HYCLATE TABLETS, USP
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Doxycycline and
other antibacterial drugs, Doxycycline should be used only to treat or
prevent infections that are proven
or strongly suspected to be caused by bacteria.
DESCRIPTION
Doxycycline is an antibacterial drug synthetically derived from
oxytetracycline, and is available as
Doxycycline Hyclate Tablets and Capsules; for oral administration.
The structural formula of doxycycline monohydrate is
with a molecular formula of C
H N O ·H O and a molecular weight of 462.46. The chemical
designation for doxycycline is
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-
pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrate.
The molecular formula
for doxycycline hydrochloride hemiethanolate hemihydrate is (C
H N O ·HCl) ·C H O·H O and the
molecular weight is 1025.89. Doxycycline is a light-yellow crystalline
powder. Doxycycline hyclate
is soluble in water, while doxycycline monohydrate is very slightly
soluble in water.
Doxycycline has a high degree of lipoid solubility and a low affinity
for calcium binding. It is highly
stable in normal human serum. Doxycycline will not degrade into an
epianhydro form.
Inactive ingredients in the capsule formulations are: colloidal
silicon dioxide, lactose anhydrous,
magnesium stearate, methylcellulose, microcrystalline cellulose,
polyethylene glycol, sodium starch
glycolate, and stearic acid. 50 mg gelatin capsule shell contains:
FD&C Blue #1, D&C Yellow #10,
titanium dioxide and gelatin. 100 mg gelatin capsule shell contains:
FD&C Blue #1, titanium dioxide and
gelatin. Black ink contains shellac glaze in SD-45, black iron oxide,
propylene glycol, FD&C Blue #2,
FD&C Red # 40, FD&C Blue # 1, D&C Yellow # 10, butyl alcohol,
denatured alcohol. Each capsule,
for oral administration, contains doxycycline hyclate