Citrex Glucosamine Chondroitin Capsule

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

Glucosamine Sulfate Potassium Chloride; CHONDROITIN SULFATE SODIUM

Boleh didapati daripada:

IDAMAN PHARMA MANUFACTURING SDN BHD

INN (Nama Antarabangsa):

Glucosamine Sulfate Potassium Chloride; CHONDROITIN SULFATE SODIUM

Unit dalam pakej:

60 Capsules; 90 Capsules; 60 Capsules; 90 Capsules

Dikeluarkan oleh:

IDAMAN PHARMA MANUFACTURING SDN BHD

Risalah maklumat

CITREX GLUCOSAMINE CHONDROITIN
CAPSULE
Glucosamine Sulfate Potassium Chloride 497.50mg equivalent to 375mg
Glucosamine Sulfate & Chondroitin Sulfate Sodium (200mg)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What Citrex Glucosamine Chondroitin
Capsule is used for
2.
How Citrex Glucosamine Chondroitin
Capsule works
3.
Before
you
use
Citrex
Glucosamine
Chondroitin Capsule
4.
How
to
use
Citrex
Glucosamine
Chondroitin Capsule
5.
While you are using it
6.
Side Effects
7.
Storage
and
Disposal
of
Citrex
Glucosamine Chondroitin Capsule
8.
Product Description
9.
Product
Registration
Holder
and
Manufacturer
10.
Date of Revision
WHAT
CITREX
GLUCOSAMINE
CHONDROITIN
CAPSULE IS USED FOR
As an adjuvant for therapy for osteoarthritis
(OA) only.
HOW
CITREX
GLUCOSAMINE
CHONDROITIN
CAPSULE WORKS
Glucosamine is a natural substance found in
chitin,
mucoproteins,
and
mucopolysaccharides. It is involved in the
manufacture of glycosaminoglycan, which
forms
cartilage
tissue
in
the
body;
glucosamine is also present in tendons and
ligaments.Glucosamine must be synthesised
by
the
body
but
the
ability
to
do
this
declines with age. Glucosamine and its salts
have
therefore
been
advocated
in
the
treatment of rheumatic disorders including
osteoarthritis.
Glucosamine
also
acts
to
improve the viscosity of synovial fluid by
increasing
synovial
fluid
production,
thereby providing lubricant activity.
Chondroitin
sulphate
is
vital
for
the
structure and function of articular cartilage.
Chondroitin
sulphate
is
an
important
component of aggrecan which is found in
articular cartilage. Aggrecan confers upon
articular
cartilage
shock-absorbing
properties.
It
does
this
by
providing
cartilage with a swelling pressure that is
restrained by the tensile force of collagen
fibers. This balance confers upon articular
cartilage the deformable resilience vital to
its function.
BEFORE
YOU
USE
CITREX
GLUCOSAMINE
CHONDROITIN CAPSULE
-
_When you must not use it _
You
must
not
take
Citrex
Glucosamine
Chondroitin
Capsule
and
should
talk
t

Ciri produk

IDAMAN PHARMA MANUFACTURING
CITREX GLUCOSAMINE CHONDROITIN CAPSULE
DESCRIPTION
Clean, uniform, dry, telescope type hard gelatin capsules.
Capsules are shiny and not smudged or sticky. Grey color
capsule.
Content of capsule:
Each
capsule
contains
Glucosamine
Sulfate
375mg
and
Chondroitin Sulfate Sodium 200mg. Off-white to yellowish in
colour.
ACTIVE SUBSTANCE(S)
•
Glucosamine
sulfate
potassium
chloride
497.50mg
equivalent to 375mg glucosamine sulfate.
•
Chondroitin sulfate sodium 200mg.
SOURCE
•
Glucosamine sulfate
potassium chloride
:
Sea Shrimp/ Crab shell
source
•
Chondroitin sulfate sodium
:
Bovine source
•
Capsule
:
Bovine source
PHARMACODYNAMICS
Glucosamine
is
a
natural
substance
found
in
chitin,
mucoproteins, and mucopolysaccharides. It is involved in the
manufacture
of
glycosaminoglycan,
which
forms
cartilage
tissue in the body; glucosamine is also present in tendons and
ligaments. Glucosamine must be synthesised by the body but
the ability to do this declines with age. Glucosamine and its
salts
have
therefore
been
advocated
in
the
treatment
of
rheumatic disorders including osteoarthritis. Glucosamine also
acts to improve the viscosity of synovial fluid by increasing
synovial fluid production, thereby providing lubricant activity.
Chondroitin sulphate is vital for the structure and function of
articular
cartilage.
Chondroitin
sulphate
is
an
important
component of aggrecan which is found in articular cartilage.
Aggrecan confers upon articular cartilage shock-absorbing
properties. It does this by providing cartilage with a swelling
pressure that is restrained by the tensile force of_ _ collagen
fibers.
This
balance
confers
upon
articular
cartilage
the
deformable resilience vital to its function.
PHARMACOKINETICS
_Absorption _
After oral administration, bioavailability is low due to first-pass
hepatic metabolism ~26%. The gastrointestinal absorption is
close to 90%.
_ _
_Distribution _
Glucosamine is not protein-bound, but rather incorporates into
plasma proteins (primarily globulins). Volume of Dis