Ceretam Oral solution 20% wv

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

PIRACETAM

Boleh didapati daripada:

AV MANUFACTURING SDN.BHD

INN (Nama Antarabangsa):

PIRACETAM

Unit dalam pakej:

120ml BOTTLE

Dikeluarkan oleh:

AV MANUFACTURING SDN.BHD

Risalah maklumat

Consumer Medication Information Leaflet (RiMUP)
CERETAM
CERETAM 800MG FILM-COATED TABLET Piracetam 800mg
CERETAM ORAL SOLUTION 20%W/V Each 5ml contains piracetam 1g
1
WHAT IS IN THIS LEAFLET
1.
What Ceretam is used for
2.
How Ceretam works
3.
Before you take Ceretam
4.
How to use Ceretam
5.
While you are using Ceretam
6.
Side effects of Ceretam
7.
Storage and Disposal
8.
Product Description
9.
Manufacturer & product
registration holder
10.
Date of revision
1.
WHAT CERETAM IS USED FOR

Treatment of the elderly with some
degree of cerebral functional
impairment such as loss of memory, a
lack of concentration or alertness and
feeling of dizziness.

Ceretam is indicated for patients
suffering from myoclonus of cortical
origin, irrespective of aetiology
(cause) and should be used in
combination with other anti-
myoclonic therapies.
2.
HOW CERETAM WORKS
Ceretam contains active ingredient
Piracetam. Piracetam acts on the brain
and the nervous system and is thought
to protect it against shortness of oxygen.
Ceretam is used in combination with
other medicines to treat myoclonus.
This is a condition causing muscles,
particularly in the arms and legs, to start
jerk or twitch uncontrollably.
3.
BEFORE YOU USE CERETAM
_When you must not use it _

If you are allergic to the active
ingredient piracetam, other
pyrrolidone derivatives or to other
ingredients of Ceretam Tablet

If you have ever had serious kidney
problems.

If you suffer from Huntington’s
Chorea (an inherited disease that
causes progressive breakdown of
nerve cells in the brain which causes
involuntary movements).

If you have ever experienced a brain
haemorrhage(bleeding).
_-Before you start to use it _
Check with your doctor

If you think your kidney may not be
working perfectly

You have ever had any kind of
bleeding problem.
_-Taking another medicines _
Tell your doctor or pharmacist if you
are taking any other medicines,
including any that you buy without a
prescription from a pharmacy,
supermarket or health food shop:

Thyroid ho

Ciri produk

CERETAM
CERETAM 800MG FILM-COATED TABLET
CERETAM ORAL SOLUTION 20%W/V
DESCRIPTION: CERETAM 800MG FILM-COATED TABLET: Each Ceretam tablet contains
piracetam 800 mg. It is a white to off- white, oblong shaped, film-coated tablet with CC logo and embossed
line on both sides of the tablet. CERETAM ORAL SOLUTION 20%W/V: Each 5ml contains piracetam 1g. It is a
clear solution with strawberry and banana flavours. Preservatives methylparaben 0.135%w/v and
propylparaben 0.015%w/v.
PHARMACODYNAMICS:
Pharmacotherapeutic group: Nootropics, ATC code: N06B X03
Mechanism of action:Piracetam's mode of action in cortical myoclonus
is as yet unknown.
Pharmacodynamic effects: Piracetam exerts its haemorrheological
effects on the platelets, red blood cells, and
vessel walls by increasing erythrocyte deformability and by decreasing
platelet aggregation, erythrocyte adhesion
to vessel walls and capillary vasospasm.
- Effects on the red blood cells:In patients with sickle cell anaemia,
piracetam improves the deformability of the
erythrocyte membrane, decreases blood viscosity, and prevents rouleaux
formation.
- Effects on platelets: In healthy volunteers and in patients with
Raynaud's phenomenon, increasing doses of
piracetam up to 12 g was associated with a dose-dependent reduction in
platelet functions compared with pre-
treatment values (tests of aggregation induced by ADP, collagen,
epinephrine and ßTG release), without significant
change in platelet count. Piracetam prolonged bleeding time.
- Effects on blood vessels: In animal studies, piracetam inhibited
vasospasm and counteracted the effects of various
spasmogenic agents. It lacked any vasodilatory action and did not
induce “steal” phenomenon, nor low or no
reflow, nor hypotensive effects.
In healthy volunteers, piracetam reduced the adhesion of RBCs to
vascular endothelium and possessed also a direct
stimulant effect on prostacycline synthesis in healthy endothelium.
-Effects on coagulation factors:In healthy volunteers, compared with
pre-treatment values, piracetam up to