Country: Kanada
Bahasa: Inggeris
Sumber: Health Canada
CEFUROXIME (CEFUROXIME SODIUM)
STERIMAX INC
J01DC02
CEFUROXIME
750MG
POWDER FOR SOLUTION
CEFUROXIME (CEFUROXIME SODIUM) 750MG
INTRAVENOUS
10ML
Prescription
SECOND GENERATION CEPHALOSPORINS
Active ingredient group (AIG) number: 0122448004; AHFS:
APPROVED
2014-03-14
_ _ Cefuroxime for Injection, USP: Product Monograph_ _ Page 1 of 33 PRODUCT MONOGRAPH PR CEFUROXIME FOR INJECTION, USP 750 mg / 10 mL vial 1.5 g / 20 mL vial 7.5 g / 100 mL Pharmacy Bulk Vial ANTIBIOTIC SteriMax Inc. 2770 Portland Drive Oakville, ON L6H 6R4 Date of Revision: August 28, 2020 Control No: 242254 _ _ Cefuroxime for Injection, USP - Product Monograph_ _ Page 2 of 33 PRODUCT MONOGRAPH PR CEFUROXIME FOR INJECTION, USP 750 mg / 10 mL vial 1.5 g / 20 mL vial 7.5 g / 100 mL Pharmacy Bulk Vial THERAPEUTIC CLASSIFICATION Antibiotic ACTION AND CLINICAL PHARMACOLOGY _In vitro _studies demonstrate that the bactericidal action of cefuroxime results from inhibition of bacterial cell wall synthesis by inhibiting the transpeptidase and carboxypeptidase enzymes. INDICATIONS AND CLINICAL USES TREATMENT Cefuroxime for Injection, USP may be indicated for the treatment of patients with infections caused by susceptible strains of the designated organisms in the following diseases: LOWER RESPIRATORY TRACT INFECTIONS: Pneumonia caused by _Streptococcus pneumoniae, Haemophilus influenzae _including ampicillin- resistant strains, _Klebsiella _species, _Staphylococcus aureus _including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus pyogenes_, and _Escherichia coli. _ _ _ URINARY TRACT INFECTIONS: Caused by _Escherichia coli_, and _Klebsiella _species. SOFT TISSUE INFECTIONS: Caused by _Staphylococcus aureus, _including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus pyogenes, Escherichia coli_, and _Klebsiella _species. MENINGITIS: Caused by _Staphylococcus aureus _including ampicillin-resistant (but not methicillin-resistant) strains, _Streptococcus pneumoniae, Haemophilus influenzae_, and _Neisseria meningitidis_. _ _ Cefuroxime for Injection, USP: Product Monograph_ _ Page 3 of 33 GONORRHEA: Caused by _Neisseria gonorrhoeae _including ampicillin-resistant strains. BONE AND JOINT INFECTIONS: Caused by _Staphylococcus aureus _(penicillinase and non-penicillinase pro Baca dokumen lengkap