Country: Amerika Syarikat
Bahasa: Inggeris
Sumber: NLM (National Library of Medicine)
BENZTROPINE MESYLATE (UNII: WMJ8TL7510) (BENZTROPINE - UNII:1NHL2J4X8K)
Contract Pharmacy Services-PA
BENZTROPINE MESYLATE
BENZTROPINE MESYLATE 1 mg
ORAL
PRESCRIPTION DRUG
Abbreviated New Drug Application
BENZTROPINE- BENZTROPINE TABLET CONTRACT PHARMACY SERVICES-PA ---------- BENZTROPINE 1MG 207 BENZTROPINE MESYLATE Tablets USP0.5 mg, 1 mg and 2 mg Leading Pharma, LLC Leading Pharma, LLC BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE ANHYDROUS DIBASIC CALCIUM PHOSPHATE LACTOSE MONOHYDRATE STARCH, CORN CELLULOSE, MICROCRYSTALLINE ANHYDROUS LACTOSE TALC CORN OIL EP;136 BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE ANHYDROUS DIBASIC CALCIUM PHOSPHATE LACTOSE MONOHYDRATE STARCH, CORN CELLULOSE, MICROCRYSTALLINE ANHYDROUS LACTOSE TALC CORN OIL EP;137 BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE MESYLATE BENZTROPINE ANHYDROUS DIBASIC CALCIUM PHOSPHATE LACTOSE MONOHYDRATE STARCH, CORN CELLULOSE, MICROCRYSTALLINE ANHYDROUS LACTOSE TALC CORN OIL EP;138 DESCRIPTION Benztropine mesylate, USP is a synthetic compound containing structural features found in atropine and diphenhydramine. It is designated chemically as 3α-(Diphenylmethoxy) -1α-H,5 α H-tropane methanesulfonate. Its molecular formula is C21H25NO•CH4O3S, and its structural formula is: Benztropine mesylate, USP is a crystalline white powder, very soluble in water, and has a molecular weight of 403.54. Each benztropine mesylate tablet, USP for oral administration contains benztropine mesylate 0.5 mg, 1 mg or 2 mg. Inactive ingredients: corn starch, dicalcium phosphate anhydrous, hydrogenated vegetable oil, lactose anhydrous, lactose monohydrate, microcrystalline cellulose, talc. Chemical structure CLINICAL PHARMACOLOGY Benztropine mesylate possesses both anticholinergic and antihistaminic effects, although only the former have been established as therapeutically significant in the management of parkinsonism. In the isolated guinea pig ileum, the anticholinergic activity of this drug is about equal to that of atropine; however, when administered orally to unanesthetized cats, it is only about half as active as atropine. In laboratory animals, its antihistaminic activity and duration of action appro Baca dokumen lengkap