AVETEN TABLET 50MG

Country: Malaysia

Bahasa: Inggeris

Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)

Bahan aktif:

ATENOLOL

Boleh didapati daripada:

APEX PHARMACY MARKETING SDN. BHD.

INN (Nama Antarabangsa):

ATENOLOL

Unit dalam pakej:

30Tablet Tablets

Dikeluarkan oleh:

DELORBIS PHARMACEUTICALS LTD.

Risalah maklumat

AVETEN TABLET
Atenolol (50mg, 100mg)
1
_CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_
WHAT IS IN THIS LEAFLET
1.
What AVETEN is used for
2.
How AVETEN works
3.
Before you take AVETEN
4.
How to take AVETEN
5.
While you are taking AVETEN
6.
Side Effects
7.
Storage and Disposal of AVETEN
8.
Product Description
9.
Manufacturer and Product
Registration Holder
10.
Date of Revision
WHAT AVETEN IS USED FOR
AVETEN is indicated for the:

Management of high blood pressure.

Management of chest pain.

Management of irregular heartbeat.

Management of the heart in the early
treatment after a heart attack.
Ask your doctor why you have to take
this medicine.
HOW AVETEN WORKS
AVETEN
belongs
to
a
group
of
medicines
called
beta-adrenergic
blockers.
These
medicines
control
the
heart rate and blood pressure.
BEFORE YOU TAKE AVETEN
-
_When you must not take it _
Do not take AVETEN:

In case of allergic to atenolol or
any of the excipients.

If
you
are
pregnant
or
breast
feeding.

If you have ever had any of the
following hear problems:
-
heart failure which is not under
control (this usually makes you
breathless
and
causes
you
ankles to swell)
-
second-
or
third-degree
heart
block (a condition which may
be treated by a pacemaker)
-
very slow or very uneven heart
beats, very low blood pressure
or very poor circulation

If
have
a
tumor
called
phaeochromocytoma
that
is
not
being treated.

If
you
have
been
told
that
you
have higher than normal levels of
acid
in
your
blood
(metabolic
acidosis)
-
_Before you start to take it _
BE CAUTIOUS WITH AVETEN

If you have poor blood circulation
or controlled heart failure.

If you have a type of chest pain
(angina)
called
Prinzmetal’s
angina.

If
you
have
first-degree
heart
block.

If you have asthma, wheezing or
any
other
similar
breathing
problems,
or
you
get
allergic
reactions,
for
example
to
insect
stings.
If
you
have
ever
had
asthma or wheezing, do not take
this
medicine
without
first
checking with your doctor.

If
you
have
diabetes.
Your
medicine

Ciri produk

COMPOSITION
Each tablet contains Atenolol 50.00 mg
Each tablet contains Atenolol 100.00 mg
PRODUCT DESCRIPTION
AVETEN TABLET 50MG: White, concave, round tablets,
9mm diameter in size, scored on one side.
AVETEN TABLET 100MG: White, flat, round tablets, 12mm
diameter in size, scored on one side.
PHARMACODYNAMICS
Atenolol is a beta- adrenoceptor blocking drug that is
beta1- selective
(i.e.
acts
preferentially
on
beta1-
adrenergic receptors in the heart). Selectivity decreases
with increasing dose.
Atenolol is without intrinsic sympathomimetic and
membrane stabilizing activities and as with other beta-
adrenoceptor blocking drugs, has negative inotropic
effects (and is therefore contraindicated in uncontrolled
heart failure).
As with other beta- adrenoceptor blocking drugs, the
mode
of
action
of
atenolol
in
the
treatment
of
hypertension is unclear. It is probably the action of
atenolol in reducing cardiac rate and contractility that
makes
it
effective
in
eliminating
or
reducing
the
symptoms of patients with angina.
It is unlikely that any additional ancillary properties
possessed by S (-) atenolol, in comparison with the
racemic mixture, will give rise to different therapeutic
effects.
Atenolol is effective and well tolerated in most ethnic
populations although the response may be less in black
patients.
Atenolol
is
compatible
with
diuretics,
other
antihypertensive agents and antianginal agents.
Early intervention with atenolol in acute myocardial
infarction reduces infarct size and decreases morbidity
and mortality. Fewer patients with a threatened infarction
progress to frank infarction; the incidence of ventricular
arrhythmias is decreased and marked pain relief may
result in reduced need of opiate analgesics. Early
mortality
is
decreased.
Atenolol
is
an
additional
treatment to standard coronary care.
PHARMACOKINETICS
Absorption
of
atenolol
following
oral
dosing
is
consistent but incomplete ( approximately 40-50%) with
peak plasma concentrations occurring 2-4 hours after
dosing. The atenolol blood levels are cons