Country: Malaysia
Bahasa: Inggeris
Sumber: NPRA (National Pharmaceutical Regulatory Agency, Bahagian Regulatori Farmasi Negara)
CHONDROITIN SULFATE SODIUM; Glucosamine Sulfate
BEST WORLD LIFESTYLE SDN. BHD.
CHONDROITIN SULFATE SODIUM; Glucosamine Sulfate
90Tablet Tablets
ECKHART CORPORATION
AVANCE® JOINT COMFORT TABLET Glucosamine Sulphate/Chondroitin Sulphate (250mg/200mg) 1 _CONSUMER MEDICATION INFORMATION LEAFLET (RIMUP)_ WHAT IS IN THIS LEAFLET 1. What Avance Joint Comfort Tablet is used for 2. How Avance Joint Comfort Tablet works 3. Before you use Avance Joint Comfort Tablet 4. How to use Avance Joint Comfort Tablet 5. While you are using it 6. Side effects 7. Storage and Disposal of Avance Joint Comfort Tablet 8. Product Description 9. Manufacturer and Product Registration Holder 10. Date of revision WHAT AVANCE JOINT COMFORT TABLET IS USED FOR Adjunctive therapy in osteoarthritis (degenerative joint disease). HOW AVANCE JOINT COMFORT TABLET WORKS Glucosamine helps to relief joint pain and stiffness by strengthening the cartilage and reduce friction around the joints. Cartilage is a connective tissue that acts as a cushion to protect the bones in the joints. Chondroitin Sulphate could potentially slow down the process of the cartilage breakdown. It gives the cartilage elasti- city by helping it to retain water hence providing resistance to compression. It also reduces the activity of enzymes and substances which will slow down the degeneration of collagen. BEFORE YOU USE AVANCE JOINT COMFORT TABLET - _When you must not use it_ Avance Joint Comfort Tablet is not meant to replace NSAIDs in cases of intense pain, as this is a causal therapy. It is advisable to take anti-inflammatory medicine in the initial treatment with glucosamine sulphate. _ _ - _Before you start to use it_ Consult your doctor if you are a. diabetic. This product derived from seafood. The effect of glucosamine on insulin sensitivity and glucose tolerance is unclear. b. having blood clot disorder _c._ having poor/ weak liver or kidney function _d._ pregnant or lactating Consult a doctor to exclude the presence of joint disease for which an alternative treatment is to be considered. - _Taking other medicines_ Consult your doctor if you are taking any other medicines or blood thinners such as warfarin. HOW TO USE AVANCE JOINT C Baca dokumen lengkap
Revision Date: 12-10-2023 AVANCE JOINT COMFORT TABLET Glucosamine Sulphate 250mg + Chondroitin Sulphate Sodium 200mg • Adjunctive Theraphy in Osteoarthritis DESCRIPTION Dark brownish white color, speckled, caplet shaped, glazed tablet. PACK SIZE 90 tablets per bottle COMPOSITION Each Tablet Contains Glucosamine Sulphate Chondroitin Sulphate Sodium (Chondroitin Sulphate 191mg) INDICATION Adjunctive therapy in osteoarthritis. RECOMMENDED DOSAGE 250mg 200mg For mild to severe cases: Take 2 tablets three times a day, before meal, for the first 1 to 2 months. For Maintenance: Take 2 tablets twice daily.before meals, from the 3rd month onward. STORAGE Store in a cool dry place below 30 ° C. Protect from light and moisture. SHELF LIFE 2 years "DERIVED FROM SHELLFISH" Reg. No: MAL20112133XC Joint Comfort Tablet manufactured by Eckhart Corp. contains Glucosamine Sulphate 250mg and Chondroitin Sulphate Sodium 200mg. Glucosamine Sulphate and Chondroitin Sulphate Sodium are substances found naturally in the body. Glucosamine possesses antiarthrosic-arthrotrophic activities. It stimulates the anabolic metabolism of osteo-cartilagineous tissue via stimulation of the biosynthesis of the mucopoly saccharides (which are the essential components of the cartilage ground-substances) and of the bone mesenchymal tissues. Glucosamine also acts to improve the viscosity of synovial fluid production, thereby providing lubricant activity. Chondroitin Sulphate could potentially slow the degeneration of the articular cartilage. Chondroitin Sulphate partially inhibits leucocyte elastase activity, which would slow the degeneration of collagen. In vitro studies have shown the Chondroitin Sulphate can increase ribonucleic acid (RNA) synthesis in cultured chondrocytes, which correlates with increased synthesis of several proteoglycans and collagens. Keep out of reach of children. PHARMACOKINETICS Glucosamine Sulphate: Glucosamine Sulphate is well absorbed (with a proportion close to 26%) following oral administration. It is known that glucosam Baca dokumen lengkap